Genome-Wide Analyses for Osteosarcoma in Leonberger Dogs Reveal the CDKN2A/B Gene Locus as a Major Risk Locus

Autor: Letko, Anna, Minor, Katie M., Norton, Elaine M., Marinescu, Voichita D., Dr��gem��ller, Michaela, Ivansson, Emma, Megquier, Kate, Noh, Hyun Ji, Starkey, Mike, Friedenberg, Steven G., Lindblad-Toh, Kerstin, Mickelson, James R., Dr��gem��ller, Cord

Publikováno v: Genes
Genes, 2021, 12 (12), ⟨10.3390/genes12121964⟩
Genes, Vol 12, Iss 1964, p 1964 (2021)
Letko, Anna; Minor, Katie M.; Norton, Elaine M.; Marinescu, Voichita D.; Drögemüller, Michaela; Ivansson, Emma; Megquier, Kate; Noh, Hyun Ji; Starkey, Mike; Friedenberg, Steven G.; Lindblad-Toh, Kerstin; Mickelson, James R.; Drögemüller, Cord (2021). Genome-Wide Analyses for Osteosarcoma in Leonberger Dogs Reveal the CDKN2A/B Gene Locus as a Major Risk Locus. Genes, 12(12), p. 1964. MDPI, Molecular Diversity Preservation International 10.3390/genes12121964

Dogs represent a unique spontaneous cancer model. Osteosarcoma (OSA) is the most common primary bone tumor in dogs (OMIA 001441-9615), and strongly resembles human forms of OSA. Several large- to giant-sized dog breeds, including the Leonberger, have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77cb2a2687d19686af1f7783c361067
http://europepmc.org/articles/PMC8700858