Výsledky vyhledávání - "Doyoun K. Song"

TRAIL Inhibits Tumor Growth but Is Nontoxic to Human Hepatocytes in Chimeric Mice

Autor: Jamie T. Lewis, Chunhai Hao, Jin H. Song, David L.J. Tyrrell, Belinda Hsi, Doyoun K. Song, Norman M. Kneteman, Kenneth C. Petruk

Publikováno v: Cancer Research. 64:8502-8506

Tumor necrosis factor (TNF) family ligand TNF-α and Fas ligand (FasL) can trigger apoptosis in solid tumors, but their clinical usage has been limited by hepatotoxicity. TNF-related apoptosis-inducing ligand (TRAIL) is a newly identified member of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3baaba46c4f1ce2fb0904cccd7d9e6
https://doi.org/10.1158/0008-5472.can-04-2599

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Role of death receptor and mitochondrial pathways in conventional chemotherapy drug induction of apoptosis

Autor: Jing Zhang, Chunhai Hao, Peng Wang, Doyoun K. Song, Jin H. Song

Publikováno v: Cellular signalling. 18(9)

The molecular mechanism underlying chemotherapy-induced apoptosis is often debated because of contradicting reports of its signaling pathway. The focus of this ongoing debate is on the requirement of a death receptor and its role in subsequent activa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a2973058b967d259cc5c454f559eba
https://pubmed.ncbi.nlm.nih.gov/16442262

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Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells

Autor: Jin H, Song, Doyoun K, Song, Meenhard, Herlyn, Kenneth C, Petruk, Chunhai, Hao

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 9(11)

Many melanoma cell lines and primary cultures are resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. In this study, we investigated the molecular mechanisms that control melanoma cell resistance and search

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9d29582cf1295db786d1fc264f6c02da
https://pubmed.ncbi.nlm.nih.gov/14519653

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TRAIL Triggers Apoptosis in Human Malignant Glioma Cells Through Extrinsic and Intrinsic Pathways

Autor: Kenneth C. Petruk, Jin H. Song, Doyoun K. Song, Beata Pyrzynska, Chunhai Hao, Erwin G. Van Meir

Publikováno v: Scopus-Elsevier
Brain Pathol
ResearcherID
Beata Pyrzynska

Many malignant glioma cells express death receptors for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), yet some of these cells are resistant to TRAIL. Here, we examined signaling events in TRAIL-induced apoptosis and searched for th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270273914907fa2475c7550a306fb6e3
http://www.scopus.com/inward/record.url?eid=2-s2.0-0242667882&partnerID=MN8TOARS

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