Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Doyel Mitra"'
Autor:
Frank E. Jones, Edi Brogi, Samuel M. Lesko, Jenny G. Parvani, Tamika T. Duplessis, Yun Zhu, Stella U. Okamgba, Michael J. Brumlik, Doyel Mitra
The HER2-targeted therapy trastuzumab is widely used for the treatment of patients with metastatic breast tumors overexpressing HER2. However, an objective response is observed in only 12% to 24% of patients treated with trastuzumab as a single agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8a27878f5ab9d8f8d30ebcfff12d2c
https://doi.org/10.1158/1535-7163.c.6531818.v1
https://doi.org/10.1158/1535-7163.c.6531818.v1
Autor:
Frank E. Jones, Edi Brogi, Samuel M. Lesko, Jenny G. Parvani, Tamika T. Duplessis, Yun Zhu, Stella U. Okamgba, Michael J. Brumlik, Doyel Mitra
Supplementary Data from An oncogenic isoform of HER2 associated with locally disseminated breast cancer and trastuzumab resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8156baa739bd70e58c55080a0beb227a
https://doi.org/10.1158/1535-7163.22485185
https://doi.org/10.1158/1535-7163.22485185
Autor:
Frank E. Jones, Edi Brogi, Samuel M. Lesko, Jenny G. Parvani, Tamika T. Duplessis, Yun Zhu, Stella U. Okamgba, Michael J. Brumlik, Doyel Mitra
Supplementary Table 1. Clinical characteristics of 85 primary breast tumors used for statistical analysis; Supplementary Table 2. HER2 and HER2�16 coexpression compared clinicopathological parameters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b968296ce569d6cb04cb32432d8bbf
https://doi.org/10.1158/1535-7163.22485182
https://doi.org/10.1158/1535-7163.22485182
Publikováno v:
The Journal of investigative dermatology
Smad4 loss occurs frequently in human skin squamous cell carcinoma (SCC), but it is unknown whether this loss increases UV-induced carcinogenesis, a major etiological factor in skin cancer. In the present study, mice with keratinocyte-specific Smad4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bedc5ccbd0e0c048679b1c905d5c10a
Autor:
Jill M. Neiman, A. H. Reddi, Ruth White, Ningjing Song, Kazutoshi Murao, Antonio Jimeno, Xian Lu, Shi-Long Lu, Fulun Li, Stephen B. Keysar, Doyel Mitra, Dennis R. Roop, Pam Fernandez, Laikuan Dionne, Gangwen Han, Li Bian, Stanca A. Birlea, Zheyi Han, Nathaniel B. Goldstein, Joshua Wisell, Xiao-Jing Wang, John I. Song, Sophia Bornstein
Publikováno v:
Journal of Clinical Investigation. 123:4390-4404
Squamous cell carcinomas (SCCs) originate in stratified epithelia, with a small subset becoming metastatic. Epithelial stem cells are targets for driver mutations that give rise to SCCs, but it is unknown whether they contribute to oncogenic multipot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1257effe55b183ccf9c52f9a0a2d4d01
https://doi.org/10.1172/jci65856
https://doi.org/10.1172/jci65856
Publikováno v:
Journal of Virology
INI1/hSNF5/SMARCB1/BAF47 is an HIV-specific integrase (IN)-binding protein that influences HIV-1 transcription and particle production. INI1 binds to SAP18 (Sin3a-associated protein, 18 kDa), and both INI1 and SAP18 are incorporated into HIV-1 virion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c698144488aded4f3ab40692e63da664
https://pubmed.ncbi.nlm.nih.gov/27558426
https://pubmed.ncbi.nlm.nih.gov/27558426
Publikováno v:
Journal of Biological Chemistry. 286:40531-40535
MicroRNAs (miRs) function as tumor suppressors or oncogenes in multiple tumor types. Although miR expression is tightly regulated, the molecular basis of miR regulation is poorly understood. Here, we investigated the influence of the histone demethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d742c81d12a35540e1620ad6e24cd6a
https://doi.org/10.1074/jbc.m111.304865
https://doi.org/10.1074/jbc.m111.304865
Autor:
Edi Brogi, Doyel Mitra, Samuel M. Lesko, Yun Zhu, Stella U. Okamgba, Tamika Duplessis, Frank E. Jones, Michael J. Brumlik, Jenny G. Parvani
Publikováno v:
Molecular Cancer Therapeutics. 8:2152-2162
The HER2-targeted therapy trastuzumab is widely used for the treatment of patients with metastatic breast tumors overexpressing HER2. However, an objective response is observed in only 12% to 24% of patients treated with trastuzumab as a single agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87bcde6dda4c17824e13f460cdaba0a6
https://doi.org/10.1158/1535-7163.mct-09-0295
https://doi.org/10.1158/1535-7163.mct-09-0295
Publikováno v:
Genetics. 172:837-849
Our previous work suggests that the Nhp6 HMGB protein stimulates RNA polymerase II transcription via the TATA-binding protein TBP and that Nhp6 functions in the same functional pathway as the Gcn5 histone acetyltransferase. In this report we examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb411ad92b91cfcdb0adee215f2fdfa
https://doi.org/10.1534/genetics.105.050245
https://doi.org/10.1534/genetics.105.050245
Autor:
Doyel Mitra, Man Mohan Johri
Publikováno v:
Journal of Biosciences. 25:331-338
Among the downstream targets of calcium in plants, calcium-dependent protein kinases (CDPKs) form an interesting class of kinases which are activated by calcium binding. They have been implicated in a diverse array of responses to hormonal and enviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5618a5969a695cf28d78ef60b379e4ab
https://doi.org/10.1007/bf02703786
https://doi.org/10.1007/bf02703786