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Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation

Autor: Dowling Catherine, Gill Catherine, O'Neill Amanda J, Watson R William G

Publikováno v: Molecular Cancer, Vol 8, Iss 1, p 39 (2009)

Abstract Background Manipulating apoptotic resistance represents an important strategy for the treatment of hormone refractory prostate cancer. We hypothesised that the Inhibitor of Apoptosis (IAP) Proteins may be mediating this resistance and knockd

Externí odkaz: https://doaj.org/article/001ce36853974812b234180a7a4a8c76

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Identification of commensal gut microbiota signatures as predictors of clinical severity and disease progression in multiple sclerosis.

Autor: Montgomery TL; Department of Biomedical and Health Sciences, University of Vermont, Burlington, VT, 05401, USA., Wang Q; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Mirza A; Pharmacoepidemiology in Multiple Sclerosis Research Group, The University of British Columbia, Vancouver, BC, V6T 2B5, Canada., Dwyer D; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Wu Q; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Dowling CA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Martens JWS; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Yang J; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, 48109, USA., Krementsov DN; Department of Biomedical and Health Sciences, University of Vermont, Burlington, VT, 05401, USA. Dimitry.Krementsov@uvm.edu., Mao-Draayer Y; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, 48109, USA. yangmaodraayer@gmail.com.; Autoimmunity Center of Excellence, Multiple Sclerosis Center of Excellence, Arthritis and Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, USA. yangmaodraayer@gmail.com.

Publikováno v: Scientific reports [Sci Rep] 2024 Jul 03; Vol. 14 (1), pp. 15292. Date of Electronic Publication: 2024 Jul 03.

Teriflunomide modulates both innate and adaptive immune capacities in multiple sclerosis.

Autor: Wu Q; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA., Wang Q; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA., Yang J; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA., Mills EA; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA., Chilukuri P; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA., Saad A; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA., Dowling CA; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA., Fisher C; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA., Kirch B; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA., Mao-Draayer Y; Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA; Graduate Program in Immunology, Program in Biomedical Sciences, University of Michigan Medical School, Ann Arbor, MI, USA; Autoimmunity Center of Excellence, University of Michigan Medical School, Ann Arbor, MI, USA.

Publikováno v: Multiple sclerosis and related disorders [Mult Scler Relat Disord] 2023 Jul; Vol. 75, pp. 104719. Date of Electronic Publication: 2023 Apr 16.