Increased potency of recombinant VWF D′D3 albumin fusion proteins engineered for enhanced affinity for coagulation factor VIII

Autor: Chia, Jenny ^*, Pestel, Sabine, Glauser, Isabelle, Emmrich, Kerstin, Hardy, Matthew P., Mischnik, Marcel, Raquet, Elmar, Tomasetig, Vesna, Claar, Philipp, Zalewski, Anton, Bass, Gregory T., Turnbull, Victor, Chen, Chao‐Guang, Wilson, Michael J., Panousis, Con, Weimer, Thomas, Andrews, Arna, Verhagen, Anne M., Dower, Steve K.

Publikováno v: In Journal of Thrombosis and Haemostasis November 2021 19(11):2710-2725

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FcRn mediates fast recycling of endocytosed albumin and IgG from early macropinosomes in primary macrophages.

Autor: Toh WH; The Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria 3010, Australia., Louber J; The Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria 3010, Australia., Mahmoud IS; The Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria 3010, Australia.; Department of Medical Laboratory Sciences, The Hashemite University, Zarqa, 13133 Jordan., Chia J; CSL Limited, Research, Bio21 Molecular Science and Biotechnology Institute, Melbourne, Victoria 3010, Australia., Bass GT; CSL Limited, Research, Bio21 Molecular Science and Biotechnology Institute, Melbourne, Victoria 3010, Australia., Dower SK; CSL Limited, Research, Bio21 Molecular Science and Biotechnology Institute, Melbourne, Victoria 3010, Australia., Verhagen AM; CSL Limited, Research, Bio21 Molecular Science and Biotechnology Institute, Melbourne, Victoria 3010, Australia., Gleeson PA; The Department of Biochemistry and Molecular Biology and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Victoria 3010, Australia pgleeson@unimelb.edu.au.

Publikováno v: Journal of cell science [J Cell Sci] 2019 Oct 01; Vol. 133 (5). Date of Electronic Publication: 2019 Oct 01.