Multi-omic profiling of simultaneous ductal carcinoma in situ and invasive breast cancer.

Autor: Kaplan HG; Swedish Cancer Institute, 1221 Madison St., Suite 920, Seattle, WA, 98104, USA. hank.kaplan@swedish.org., Dowdell AK; Earle A. Chiles Research Institute, Providence Health, Portland, OR, 97213, USA., Berry AB; Swedish Cancer Institute, 1221 Madison St., Suite 920, Seattle, WA, 98104, USA., Shimol RB; Earle A. Chiles Research Institute, Providence Health, Portland, OR, 97213, USA., Robinson FL; Earle A. Chiles Research Institute, Providence Health, Portland, OR, 97213, USA., Carney CA; Swedish Cancer Institute, 1221 Madison St., Suite 920, Seattle, WA, 98104, USA., Piening BD; Earle A. Chiles Research Institute, Providence Health, Portland, OR, 97213, USA.

Publikováno v: Breast cancer research and treatment [Breast Cancer Res Treat] 2024 Jun; Vol. 205 (3), pp. 451-464. Date of Electronic Publication: 2024 Mar 24.

Integrative multi-omics profiling in human decedents receiving pig heart xenografts.

Autor: Schmauch E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA., Piening B; Earle A. Chiles Research Institute, Providence Cancer Center, Portland, OR, USA., Mohebnasab M; Division of Molecular Genetics Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Xia B; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA.; Society of Fellows, Harvard University, Cambridge, MA, USA., Zhu C; Department of Genetics, Stanford University, Stanford, CA, USA., Stern J; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Zhang W; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Dowdell AK; Earle A. Chiles Research Institute, Providence Cancer Center, Portland, OR, USA., Kim JI; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Andrijevic D; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Khalil K; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA., Jaffe IS; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Loza BL; Penn Transplant Institute, University of Pennsylvania, Philadelphia, PA, USA., Gragert L; Division of Biomedical Informatics and Genomics, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Camellato BR; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Oliveira MF; 10x Genomics, Pleasanton, CA, USA., O'Brien DP; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Chen HM; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Weldon E; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Gao H; Penn Transplant Institute, University of Pennsylvania, Philadelphia, PA, USA., Gandla D; Penn Transplant Institute, University of Pennsylvania, Philadelphia, PA, USA., Chang A; Penn Transplant Institute, University of Pennsylvania, Philadelphia, PA, USA., Bhatt R; Penn Transplant Institute, University of Pennsylvania, Philadelphia, PA, USA., Gao S; Penn Transplant Institute, University of Pennsylvania, Philadelphia, PA, USA., Lin X; Department of Genetics, Stanford University, Stanford, CA, USA., Reddy KP; Penn Transplant Institute, University of Pennsylvania, Philadelphia, PA, USA., Kagermazova L; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA., Habara AH; Department of Biochemistry, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia., Widawsky S; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Liang FX; DART Microscopy Laboratory, NYU Langone Health, New York, NY, USA., Sall J; DART Microscopy Laboratory, NYU Langone Health, New York, NY, USA., Loupy A; Université Paris Cité, Paris Institute for Transplantation and Organ Regeneration, Paris, France., Heguy A; Genome Technology Center, NYU Langone Health, New York, NY, USA., Taylor SEB; 10x Genomics, Pleasanton, CA, USA., Zhu Y; Division of Molecular Genetics Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Michael B; Department of Genetics, Stanford University, Stanford, CA, USA., Jiang L; Department of Genetics, Stanford University, Stanford, CA, USA., Jian R; Department of Genetics, Stanford University, Stanford, CA, USA., Chong AS; Department of Surgery, The University of Chicago, Chicago, IL, USA., Fairchild RL; Department of Inflammation and Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA., Linna-Kuosmanen S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Kaikkonen MU; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Tatapudi V; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Lorber M; United Therapeutics, Silver Spring, MD, USA., Ayares D; Revivicor, Blacksburg, VA, USA., Mangiola M; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA., Narula N; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Pathology, NYU Grossman School of Medicine, New York, NY, USA., Moazami N; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Cardiothoracic Surgery, NYU Langone Health, New York, NY, USA., Pass H; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Cardiothoracic Surgery, NYU Langone Health, New York, NY, USA., Herati RS; Department of Medicine, NYU Grossman School of Medicine, New York, NY, USA., Griesemer A; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Kellis M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA., Snyder MP; Department of Genetics, Stanford University, Stanford, CA, USA., Montgomery RA; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA., Boeke JD; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA.; Department of Biochemistry and Molecular Pharmacology, NYU Langone Health, New York, NY, USA.; Department of Biomedical Engineering, NYU Tandon School of Engineering, Brooklyn, NY, USA., Keating BJ; Institute for Systems Genetics, NYU Langone Health, New York, NY, USA. brendan.keating@nyulangone.org.; NYU Langone Transplant Institute, NYU Langone Health, New York, NY, USA. brendan.keating@nyulangone.org.; Department of Surgery, NYU Grossman School of Medicine, New York, NY, USA. brendan.keating@nyulangone.org.

Publikováno v: Nature medicine [Nat Med] 2024 May; Vol. 30 (5), pp. 1448-1460. Date of Electronic Publication: 2024 May 17.

Myeloid MyD88 restricts CD8 ⁺ T cell response to radiation therapy in pancreatic cancer.

Autor: Medler TR; Earle A. Chiles Research Institute, Providence Cancer Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan Street, Suite 2N100, Portland, OR, 97213, USA., Blair TC; Earle A. Chiles Research Institute, Providence Cancer Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan Street, Suite 2N100, Portland, OR, 97213, USA., Alice AF; Earle A. Chiles Research Institute, Providence Cancer Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan Street, Suite 2N100, Portland, OR, 97213, USA., Dowdell AK; Earle A. Chiles Research Institute, Providence Cancer Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan Street, Suite 2N100, Portland, OR, 97213, USA., Piening BD; Earle A. Chiles Research Institute, Providence Cancer Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan Street, Suite 2N100, Portland, OR, 97213, USA., Crittenden MR; Earle A. Chiles Research Institute, Providence Cancer Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan Street, Suite 2N100, Portland, OR, 97213, USA.; The Oregon Clinic, Portland, OR, USA., Gough MJ; Earle A. Chiles Research Institute, Providence Cancer Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, 4805 NE Glisan Street, Suite 2N100, Portland, OR, 97213, USA. michael.gough@providence.org.

Publikováno v: Scientific reports [Sci Rep] 2023 May 27; Vol. 13 (1), pp. 8634. Date of Electronic Publication: 2023 May 27.

Whole transcriptome profiling of prospective endomyocardial biopsies reveals prognostic and diagnostic signatures of cardiac allograft rejection.

Autor: Piening BD; Earle A. Chiles Research Institute, Providence, Portland, Oregon; Department of Genetics, Stanford University School of Medicine, Stanford, California., Dowdell AK; Earle A. Chiles Research Institute, Providence, Portland, Oregon., Zhang M; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Loza BL; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Walls D; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Gao H; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Mohebnasab M; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania; Department of Pathology, Oregon Health and Sciences University, Portland, Oregon., Li YR; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Elftmann E; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Wei E; Department of Genetics, Stanford University School of Medicine, Stanford, California., Gandla D; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Lad H; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Chaib H; Department of Genetics, Stanford University School of Medicine, Stanford, California., Sweitzer NK; Division of Cardiology, University of Arizona, Tucson, Arizona., Deng M; Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, California., Pereira AC; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School Hospital, São Paulo, Brazil., Cadeiras M; Division of Cardiovascular Medicine, University of California Davis, Davis, California., Shaked A; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania., Snyder MP; Department of Genetics, Stanford University School of Medicine, Stanford, California., Keating BJ; Division of Transplantation, Department of Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: bkeating@pennmedicine.upenn.edu.

Publikováno v: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2022 Jun; Vol. 41 (6), pp. 840-848. Date of Electronic Publication: 2022 Feb 03.

Obesity Drives Delayed Infarct Expansion, Inflammation, and Distinct Gene Networks in a Mouse Stroke Model.

Autor: Peterson TC; Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, CA, USA.; Department of Psychology, University of North Carolina Wilmington, Wilmington, NC, USA., Lechtenberg KJ; Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, CA, USA., Piening BD; Department of Genetics, Stanford School of Medicine, Palo Alto, CA, USA.; Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR, USA., Lucas TA; Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, CA, USA., Wei E; Department of Genetics, Stanford School of Medicine, Palo Alto, CA, USA., Chaib H; Department of Genetics, Stanford School of Medicine, Palo Alto, CA, USA., Dowdell AK; Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR, USA., Snyder M; Department of Genetics, Stanford School of Medicine, Palo Alto, CA, USA., Buckwalter MS; Department of Neurology and Neurological Sciences, Stanford School of Medicine, Palo Alto, CA, USA. marion.buckwalter@stanford.edu.; Department of Neurosurgery, Stanford School of Medicine, Palo Alto, CA, USA. marion.buckwalter@stanford.edu.; Department of Neurology and Neurological Sciences and Department of Neurosurgery, Stanford University, P209 MSLS Building, 1201 Welch Road, Stanford, CA, 94305, USA. marion.buckwalter@stanford.edu.

Publikováno v: Translational stroke research [Transl Stroke Res] 2021 Apr; Vol. 12 (2), pp. 331-346. Date of Electronic Publication: 2020 Jun 25.