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Autor:
Dow, Geoffrey S, Smith, Bryan
Publikováno v:
Journal of Infectious Diseases; 7/15/2024, Vol. 230 Issue 1, p271-272, 2p
Autor:
Dow, Geoffrey S.1 geoffdow@60degreespharma.com, Jun Liu2, Gina Lin2, Hetzell, Brian2, Thieling, Sarah2, McCarthy, William F.3, Tang, Douglas3, Smith, Bryan3
Publikováno v:
Malaria Journal. 11/26/2015, Vol. 14 Issue 1, p1-13. 13p. 3 Diagrams, 10 Charts, 1 Graph.
Autor:
Kenworthy David, Milhous Wilbur, Cozens Simon, Kyle Dennis, Sattabongkot Jetsumon, Komcharoen Srawuth, Imerbsin Rawiwan, Hansukjariya Pranee, Gettayacamin Montip, Dow Geoffrey S, Miller Anne, Veazey Jim, Ohrt Colin
Publikováno v:
Malaria Journal, Vol 10, Iss 1, p 212 (2011)
Abstract Background Tafenoquine is an 8-aminoquinoline being developed for radical cure (blood and liver stage elimination) of Plasmodium vivax. During monotherapy treatment, the compound exhibits slow parasite and fever clearance times, and toxicity
Externí odkaz:
https://doaj.org/article/4652ddc4570e4f228e66482e90a287f9
Autor:
Shackleford David M, Roncal Norma, Norval Suzanne, Read Kevin D, Moon Jay, McCalmont William, Mannila Anne, Lanteri Charlotte, Kozar Michael, Gerena Lucia, Gardner Sean, Caridha Diana, Bhonsle Jayendra, Bathurst Ian, Milner Erin, Dow Geoffrey S, Sousa Jason, Steuten Jessica, White Karen L, Zeng Qiang, Charman Susan A
Publikováno v:
Malaria Journal, Vol 10, Iss 1, p 150 (2011)
Abstract Background The clinical use of mefloquine (MQ) has declined due to dose-related neurological events. Next generation quinoline methanols (NGQMs) that do not accumulate in the central nervous system (CNS) to the same extent may have utility.
Externí odkaz:
https://doaj.org/article/3e5c5bb33573479babc7ca7502e11bd6
Autor:
Dow, Geoffrey S.1 geoffdow@hotmail.com, McCarthy, William F.1 william.f.mccarthy1@us.army.mil, Reid, Mark2 mark.reid@clinical.net.au, Smith, Bryan1 bryan.l.smith@us.army.mil, Tang, Douglas1 dtang38@verizon.net, Shanks, G. Dennis3 Dennis.SHANKS@defence.gov.au
Publikováno v:
Malaria Journal. 2014, Vol. 13 Issue 1, p1-22. 22p. 5 Charts.
Publikováno v:
Malaria Journal, Vol 2, Iss 1, p 14 (2003)
Abstract Background There is no established biochemical basis for the neurotoxicity of mefloquine. We investigated the possibility that the acute in vitro neurotoxicity of mefloquine might be mediated through a disruptive effect of the drug on endopl
Externí odkaz:
https://doaj.org/article/481770311eed415da50f2808e806ca16
Autor:
Dow Geoffrey S
Publikováno v:
Malaria Journal, Vol 2, Iss 1, p 4 (2003)
Abstract Background There is no known biochemical basis for the adverse neurological events attributed to mefloquine. Identification of genes modulated by toxic agents using microarrays may provide sufficient information to generate hypotheses regard
Externí odkaz:
https://doaj.org/article/35434b4555e14c97954545739527409d
Autor:
Dow, Geoffrey S.1 geoffrey.dow@us.army.mil, Milner, Erin1, Bathurst, Ian2, Bhonsle, Jayendra1, Caridha, Diana1, Gardner, Sean1, Gerena, Lucia1, Kozar, Michael1, Lanteri, Charlotte1, Mannila, Anne3, McCalmont, William1, Moon, Jay1, Read, Kevin D.4, Norval, Suzanne4, Roncal, Norma1, Shackleford, David M.3, Sousa, Jason1, Steuten, Jessica3, White, Karen L.3, Qiang Zeng1
Publikováno v:
Malaria Journal. 2011 Supplement 1, Vol. 10 Issue Suppl 1, p150-160. 11p.
Autor:
Dow, Geoffrey S.1 geoffrey.dow@na.amedd.army.mil, Hudson, Thomas H.1 thomas.hudson@na.amedd.army.mil, Vahey, Maryanne2 mvahey@hivresearch.org, Koenig, Michael L.3 michael.koenig@na.amedd.army.mil
Publikováno v:
Malaria Journal. 2003, Vol. 2, p1-14. 14p. 3 Charts, 6 Graphs.