Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Dov Shiffman"'
Autor:
Judy Z. Louie, Dov Shiffman, Charles M. Rowland, Norma S. Kenyon, Ernesto Bernal-Mizrachi, Michael J. McPhaul, Rajesh Garg
Publikováno v:
Clinical Diabetes and Endocrinology, Vol 10, Iss 1, Pp 1-8 (2024)
Abstract Background Professional guidelines recommend an HbA1c 8.5% within 3 years from their last HbA1c were included in analysis. Patients were grouped as improved glycemic control (last HbA1c ≤ 8.5%) or lack of improvement (last HbA1c > 8.5%). M
Externí odkaz:
https://doaj.org/article/ef12b0c86b5c403194af57ff2313cba1
Publikováno v:
American Journal of Preventive Cardiology, Vol 13, Iss , Pp 100457- (2023)
Objective: Insulin resistance (IR) increases risk of type 2 diabetes and atherosclerotic cardiovascular disease and is associated with lipid and lipoprotein abnormalities including high triglycerides (TG) and low high-density lipoprotein cholesterol
Externí odkaz:
https://doaj.org/article/1458cafeb9344a1db2cb4f40ef3b7d8d
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 9 (2020)
Background The American Heart Association and American College of Cardiology guidelines defined patient‐management groups that would benefit from lowering of low‐density lipoprotein cholesterol (LDL‐C). We assessed gaps in dyslipidemia care amo
Externí odkaz:
https://doaj.org/article/d7b1a60909e941c995b851c21634df1c
Autor:
Charles M Rowland, Dov Shiffman, Michael Caulfield, Veronica Garcia, Olle Melander, Trevor Hastie
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213172 (2019)
BackgroundFunctional data is data represented by functions (curves or surfaces of a low-dimensional index). Functional data often arise when measurements are collected over time or across locations. In the field of medicine, plasma lipoprotein partic
Externí odkaz:
https://doaj.org/article/92dc0767ac2d47eb9612891921f7f424
Autor:
Evan D Muse, Nathan E Wineinger, Emily G Spencer, Melissa Peters, Riley Henderson, Yunyue Zhang, Paddy M Barrett, Steven P Rivera, Jay G Wohlgemuth, James J Devlin, Dov Shiffman, Eric J Topol
Publikováno v:
PLoS Medicine, Vol 15, Iss 3, p e1002525 (2018)
BACKGROUND:Atrial fibrillation (AF) is the most commonly encountered arrhythmia and is associated with an elevated risk of stroke. Improving the identification of patients with the highest risk for AF to enable appropriate surveillance and treatment,
Externí odkaz:
https://doaj.org/article/d701d336108445adbdc4280560031ae0
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 3 (2017)
Background Family history of coronary heart disease (CHD) as well as genetic predisposition to CHD assessed by a genetic risk score (GRS) are predictors of CHD risk. It is, however, uncertain to what extent these risk predictors are mediated by major
Externí odkaz:
https://doaj.org/article/47f9208a15064c139a267f7aa5a957bb
Autor:
Dov Shiffman, Guillaume Pare, Rainer Oberbauer, Judy Z Louie, Charles M Rowland, James J Devlin, Johannes F Mann, Matthew J McQueen
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106631 (2014)
Although albuminuria and subsequent advanced stage chronic kidney disease are common among patients with diabetes, the rate of increase in albuminuria varies among patients. Since genetic variants associated with estimated glomerular filtration rate
Externí odkaz:
https://doaj.org/article/add43baa47684cbd82f2392de3b9f0f7
Autor:
Dov Shiffman, Stella Trompet, Judy Z Louie, Charles M Rowland, Joseph J Catanese, Olga A Iakoubova, Todd G Kirchgessner, Rudi G J Westendorp, Anton J M de Craen, P Eline Slagboom, Brendan M Buckley, David J Stott, Naveed Sattar, James J Devlin, Christopher J Packard, Ian Ford, Frank M Sacks, J Wouter Jukema
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38240 (2012)
Statin therapy reduces the risk of coronary heart disease (CHD), however, the person-to-person variability in response to statin therapy is not well understood. We have investigated the effect of genetic variation on the reduction of CHD events by pr
Externí odkaz:
https://doaj.org/article/5a50004cb4ee493b98d67bc19cf69fe5
Autor:
Guillaume Paré, Paul M Ridker, Lynda Rose, Maja Barbalic, Josée Dupuis, Abbas Dehghan, Joshua C Bis, Emelia J Benjamin, Dov Shiffman, Alexander N Parker, Daniel I Chasman
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1001374 (2011)
Soluble ICAM-1 (sICAM-1) is an endothelium-derived inflammatory marker that has been associated with diverse conditions such as myocardial infarction, diabetes, stroke, and malaria. Despite evidence for a heritable component to sICAM-1 levels, few ge
Externí odkaz:
https://doaj.org/article/7cdf24c30b454875ab3a116610ae568b
Autor:
Dov Shiffman, John P Kane, Judy Z Louie, Andre R Arellano, David A Ross, Joseph J Catanese, Mary J Malloy, Stephen G Ellis, James J Devlin
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2895 (2008)
Myocardial infarction (MI) is a common complex disease with a genetic component. While several single nucleotide polymorphisms (SNPs) have been reported to be associated with risk of MI, they do not fully explain the observed genetic component of MI.
Externí odkaz:
https://doaj.org/article/c8c0b7dc9e724c61926f7abff11286b3