Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Dov H. Pluznik"'
Experimental Hematology Today - 1988 presents the latest results of research reflecting the diverse interests of basic and clinical hematologists. The major areas explored are hematopoietic regulation by cytokines; hematopoietic cellular growth regul
Publikováno v:
Blood. 82:2641-2648
The murine myeloid leukemia cell line M1 induced by interleukin-6 (IL- 6) is a model system to study the differentiation of blast cells to mature macrophages. We have recently shown that IL-6 induces the expression of the IL-4 receptor (IL-4R) in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ec594405dfd25d17381c805c58f607
https://doi.org/10.1182/blood.v82.9.2641.2641
https://doi.org/10.1182/blood.v82.9.2641.2641
Publikováno v:
Human Gene Therapy. 4:283-290
The retroviral vector LGSN, in which the human glucocerebrosidase (GC) cDNA is driven by the Moloney murine leukemia virus (MoMLV) long terminal repeat (LTR), was tested for expression in the murine myelomonocytic leukemia cell line M1 before and aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6cf51e3a3d782534cdb11a8e63d2601
https://doi.org/10.1089/hum.1993.4.3-283
https://doi.org/10.1089/hum.1993.4.3-283
Autor:
Stefan Ruhl, Dov H. Pluznik
Publikováno v:
Journal of Cellular Physiology. 155:130-138
Murine myeloid leukemia M1 cells undergo terminal differentiation to mature macrophages after stimulation with interleukin-6 (IL-6). This process can be monitored by measuring the expression of early markers such as the high affinity receptor for mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d9121f316e2be229e5616f97b31f9b
https://doi.org/10.1002/jcp.1041550117
https://doi.org/10.1002/jcp.1041550117
Publikováno v:
Proceedings of the National Academy of Sciences. 89:10001-10005
Adenosine+uridine (AU)-rich sequences in the 3' untranslated region (3'UTR) of the mRNA of many cytokines and oncogenes play an important role in mediating RNA degradation. Among the cytokines containing such AU-rich sequences in their 3'UTR is the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c294e8b40e9f6a314b9b2f8eb15ba6f
https://doi.org/10.1073/pnas.89.21.10001
https://doi.org/10.1073/pnas.89.21.10001
Autor:
Dov H. Pluznik, K Akahane
Publikováno v:
Blood. 79:3188-3195
Interleukin-4 (IL-4) regulates the growth of B cells. When combined with colony-stimulating factors (CSFs) and selected cytokines, IL-4 has a synergistic effect on the clonal growth of bone marrow cells. Recently, we have shown that IL-1 alpha and li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4fe57847125c910cb96de23850985c1
https://doi.org/10.1182/blood.v79.12.3188.bloodjournal79123188
https://doi.org/10.1182/blood.v79.12.3188.bloodjournal79123188
Publikováno v:
Blood. 78:1678-1684
Interleukin-4 (IL-4) is a T-cell-derived cytokine that regulates induction of proliferation of resting B cells and acts on various other immunocompetent cells, such as monocytes/macrophages and mast cells, as well as hematopoietic progenitor cells. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5065ada54379aa7f978599716fb5872
https://doi.org/10.1182/blood.v78.7.1678.1678
https://doi.org/10.1182/blood.v78.7.1678.1678
Publikováno v:
Cytokine. 5(2)
Soluble cytokine receptors, molecules that can selectively modulate the effects of a single cytokine, have generated great interest both as indicators of disease and as targeted immunotherapeutic agents. However, cellular sources for soluble cytokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3abc533b4761cb64c7d05163538d74
https://pubmed.ncbi.nlm.nih.gov/8334228
https://pubmed.ncbi.nlm.nih.gov/8334228
Autor:
Dov H. Pluznik, Matthias Bickel, Stefan Ruhl, Carl W. Dieffenbach, Sharon B. Midura, Gabriela S. Dveksler
Publikováno v:
Cytokine. 2(4)
Interleukin 6 (IL 6) induces differentiation of murine myelomonocytic leukemia (M1) cells into mature macrophages. This process is monitored by the sequential appearance of surface markers, induction of intracellular enzymes, and changes in morpholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b050ad1ae1a03977a9297e61831e051f
https://pubmed.ncbi.nlm.nih.gov/2104240
https://pubmed.ncbi.nlm.nih.gov/2104240
Publikováno v:
Transplantation. 49(4)
Injection of parental C57BL/10 spleen cells into unirradiated immune-competent (B10 x B10.BR)F1 hosts has been demonstrated to produce a graft-vs.-host-induced immune deficiency in T cell-mediated functions, including mitogen or alloantigen stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5441b7c2d984eb08fd4177196470997f
https://pubmed.ncbi.nlm.nih.gov/2183411
https://pubmed.ncbi.nlm.nih.gov/2183411