Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Dov A. Pechenick"'
Autor:
Rodwell Mabaera, Randolph J. Noelle, David A. Leib, Chao Cheng, Frederick S. Varn, Christopher H. Lowrey, Isabelle Le Mercier, Richard Manivanh, Dov A. Pechenick, David C. Qian, Yu-Chi Lee, J. Louise Lines, Aurelien Sarde, Jiannan Li, Jie Deng
Tumor hypoxia is a negative prognostic factor that is implicated in oncogenic signal activation, immune escape, and resistance to treatment. Identifying the mechanistic role of hypoxia in immune escape and resistance to immune-checkpoint inhibitors m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949804db5e7d6c80642766b2bbbdc66e
https://doi.org/10.1158/2326-6066.c.6549897
https://doi.org/10.1158/2326-6066.c.6549897
Autor:
Rodwell Mabaera, Randolph J. Noelle, David A. Leib, Chao Cheng, Frederick S. Varn, Christopher H. Lowrey, Isabelle Le Mercier, Richard Manivanh, Dov A. Pechenick, David C. Qian, Yu-Chi Lee, J. Louise Lines, Aurelien Sarde, Jiannan Li, Jie Deng
Supplementary Methods and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622a10c668596dce71cdf77357503f9a
https://doi.org/10.1158/2326-6066.22542372.v1
https://doi.org/10.1158/2326-6066.22542372.v1
Autor:
Rodwell Mabaera, Randolph J. Noelle, David A. Leib, Chao Cheng, Frederick S. Varn, Christopher H. Lowrey, Isabelle Le Mercier, Richard Manivanh, Dov A. Pechenick, David C. Qian, Yu-Chi Lee, J. Louise Lines, Aurelien Sarde, Jiannan Li, Jie Deng
Figure S2. Vista expression is correlated with myeloid infiltration in the TME of colon cancer patients. Volcano plot of CLS differences (granulocytic, monocytic, and αβ T cells) between VISTAhigh and VISTAlow cohorts and the associated significanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d9c19353a01304e5354684d00c0541
https://doi.org/10.1158/2326-6066.22542375.v1
https://doi.org/10.1158/2326-6066.22542375.v1
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 8, p e1003780 (2014)
Many developmental, physiological, and behavioral processes depend on the precise expression of genes in space and time. Such spatiotemporal gene expression phenotypes arise from the binding of sequence-specific transcription factors (TFs) to DNA, an
Externí odkaz:
https://doaj.org/article/732be70d4a454b858b81601e2093c1de
Autor:
Rodwell Mabaera, J. Louise Lines, Randolph J. Noelle, Jie Deng, Jiannan Li, Richard Manivanh, Dov A. Pechenick, Aurelien Sarde, Christopher H. Lowrey, Yu-Chi Lee, Isabelle Le Mercier, Frederick S. Varn, Chao Cheng, David C. Qian, David A. Leib
Publikováno v:
Cancer Immunol Res
Tumor hypoxia is a negative prognostic factor that is implicated in oncogenic signal activation, immune escape, and resistance to treatment. Identifying the mechanistic role of hypoxia in immune escape and resistance to immune-checkpoint inhibitors m
Autor:
Randolph J. Noelle, Susan K. Eszterhas, Li Wang, Christopher M. Burns, David A. Armstrong, Alix Ashare, Matthew P. Vincenti, Petra A. Sergent, Sabrina Ceeraz, Thomas Broughton, Dov A. Pechenick, Roy A. Fava
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-13 (2017)
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-13 (2017)
Background In addition to activated T cells, the immune checkpoint inhibitor “V domain-containing Ig suppressor of T-cell activation” (VISTA) is expressed by myeloid cell types, including macrophages and neutrophils. The importance of VISTA expre
Autor:
Randolph J. Noelle, Christopher M. Burns, Petra A. Sergent, J Pettus, Rodwell Mabaera, Sabrina Ceeraz, J K DeLong, S F Plummer, Dov A. Pechenick
Publikováno v:
Lupus
V-domain Ig suppressor of T-cell activation (VISTA) is a critical negative checkpoint molecule involved in regulating the immune response. Targeting the pathway with an antagonist anti-VISTA antibody designated 13F3 has been shown to enhance disease
Autor:
Richard W Michelmore, Dov A. Pechenick, Oswaldo E. Ochoa, Ivan Simko, Maria Jose Truco, Leah K. McHale, Brian E. Scheffler
Publikováno v:
Acta Horticulturae. :401-408
Lettuce dieback disease is widespread in commercially grown romaine and leaf-type lettuces, but not in iceberg-type cultivars. The disease is caused by two closely related Tombusviruses: Tomato bushy stunt virus (TBSV) and Lettuce necrotic stunt viru
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 8, p e1003780 (2014)
PLoS Computational Biology
PLoS Computational Biology
Many developmental, physiological, and behavioral processes depend on the precise expression of genes in space and time. Such spatiotemporal gene expression phenotypes arise from the binding of sequence-specific transcription factors (TFs) to DNA, an
Publikováno v:
ECAL
Gene regulatory networks (GRNs) comprise the interacting genes and gene products that drive genetic regulation within the cell. Because of the vital role they play in producing cell function, GRNs are robust to a variety of perturbations, including g