Zobrazeno 1 - 10 of 323 pro vyhledávání: '"Douty B"'
1
Akademický článek
Parsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell Malignancy.
Autor: Shin N; Incyte Research Institute, Wilmington, Delaware nshin@incyte.com., Stubbs M; Incyte Research Institute, Wilmington, Delaware., Koblish H; Incyte Research Institute, Wilmington, Delaware., Yue EW; Incyte Research Institute, Wilmington, Delaware., Soloviev M; Incyte Research Institute, Wilmington, Delaware., Douty B; Incyte Research Institute, Wilmington, Delaware., Wang KH; Incyte Research Institute, Wilmington, Delaware., Wang Q; Incyte Research Institute, Wilmington, Delaware., Gao M; Incyte Research Institute, Wilmington, Delaware., Feldman P; Incyte Research Institute, Wilmington, Delaware., Yang G; Incyte Research Institute, Wilmington, Delaware., Hall L; Incyte Research Institute, Wilmington, Delaware., Hansbury M; Incyte Research Institute, Wilmington, Delaware., O'Connor S; Incyte Research Institute, Wilmington, Delaware., Leffet L; Incyte Research Institute, Wilmington, Delaware., Collins R; Incyte Research Institute, Wilmington, Delaware., Katiyar K; Incyte Research Institute, Wilmington, Delaware., He X; Incyte Research Institute, Wilmington, Delaware., Waeltz P; Incyte Research Institute, Wilmington, Delaware., Collier P; Incyte Research Institute, Wilmington, Delaware., Lu J; Incyte Research Institute, Wilmington, Delaware., Li YL; Incyte Research Institute, Wilmington, Delaware., Li Y; Incyte Research Institute, Wilmington, Delaware., Liu PCC; Incyte Research Institute, Wilmington, Delaware., Burn T; Incyte Research Institute, Wilmington, Delaware., Covington M; Incyte Research Institute, Wilmington, Delaware., Diamond S; Incyte Research Institute, Wilmington, Delaware., Shuey D; Incyte Research Institute, Wilmington, Delaware., Roberts A; Incyte Research Institute, Wilmington, Delaware., Yeleswaram S; Incyte Research Institute, Wilmington, Delaware., Hollis G; Incyte Research Institute, Wilmington, Delaware., Metcalf B; Incyte Research Institute, Wilmington, Delaware., Yao W; Incyte Research Institute, Wilmington, Delaware., Huber R; Incyte Research Institute, Wilmington, Delaware., Combs A; Incyte Research Institute, Wilmington, Delaware., Newton R; Incyte Research Institute, Wilmington, Delaware., Scherle P; Incyte Research Institute, Wilmington, Delaware.
Publikováno v: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2020 Jul; Vol. 374 (1), pp. 211-222. Date of Electronic Publication: 2020 Apr 28.
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2
Akademický článek
Targeting PI3K family with small-molecule inhibitors in cancer therapy: current clinical status and future directions.
Autor: Li, Hongyao1,2,3 (AUTHOR), Wen, Xiang3 (AUTHOR), Ren, Yueting3,4 (AUTHOR), Fan, Zhichao1,2,3 (AUTHOR), Zhang, Jin5 (AUTHOR) zhangjin1989@szu.edu.cn, He, Gu3 (AUTHOR) hegu@scu.edu.cn, Fu, Leilei1,2 (AUTHOR) leilei_fu@163.com
Publikováno v: Molecular Cancer. 8/10/2024, Vol. 23 Issue 1, p1-42. 42p.
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3
Akademický článek
Pembrolizumab plus epacadostat in patients with recurrent/metastatic head and neck squamous cell carcinoma (KEYNOTE-669/ECHO-304): a phase 3, randomized, open-label study.
Autor: Cho, Byoung Chul1,2 (AUTHOR) cbc1971@yuhs.ac, Braña, Irene3 (AUTHOR), Cirauqui, Beatriz4 (AUTHOR), Aksoy, Sercan5 (AUTHOR), Couture, Felix6 (AUTHOR), Hong, Ruey-Long7 (AUTHOR), Miller Jr, Wilson H.8 (AUTHOR), Chaves-Conde, Manuel9 (AUTHOR), Teixeira, Margarida10 (AUTHOR), Leopold, Lance11 (AUTHOR), Munteanu, Mihaela11 (AUTHOR), Ge, Joy Yang12 (AUTHOR), Swaby, Ramona F.12 (AUTHOR), Hughes, Brett G. M.13 (AUTHOR)
Publikováno v: BMC Cancer. 7/25/2024, Vol. 23 Issue 1, p1-12. 12p.
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4
Akademický článek
INCB050465 (Parsaclisib), a Novel Next-Generation Inhibitor of Phosphoinositide 3-Kinase Delta (PI3Kδ).
Autor: Yue EW; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Li YL; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Douty B; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., He C; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Mei S; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Wayland B; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Maduskuie T; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Falahatpisheh N; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Sparks RB; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Polam P; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Zhu W; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Glenn J; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Feng H; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Zhang K; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Li Y; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., He X; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Katiyar K; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Covington M; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Feldman P; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Shin N; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Wang KH; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Diamond S; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Li Y; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Koblish HK; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Hall L; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Scherle P; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Yeleswaram S; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Xue CB; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Metcalf B; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Combs AP; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Yao W; Incyte Research Institute, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States.
Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Oct 17; Vol. 10 (11), pp. 1554-1560. Date of Electronic Publication: 2019 Oct 17 (Print Publication: 2019).
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5
Akademický článek
Mulberry Leaf Compounds and Gut Microbiota in Alzheimer's Disease and Diabetes: A Study Using Network Pharmacology, Molecular Dynamics Simulation, and Cellular Assays.
Autor: Bai, Xue1 (AUTHOR) baix23@mails.jlu.edu.cn, Zhao, Xinyi1 (AUTHOR) xinyiz21@mails.jlu.edu.cn, Liu, Kaifeng1 (AUTHOR) liukf1220@mails.jlu.edu.cn, Yang, Xiaotang1 (AUTHOR) yangxt22@mails.jlu.edu.cn, He, Qizheng1 (AUTHOR) heqz9923@mails.jlu.edu.cn, Gao, Yilin1 (AUTHOR) gaoyl2321@mails.jlu.edu.cn, Li, Wannan2 (AUTHOR) liwannan@jlu.edu.cn, Han, Weiwei1 (AUTHOR) liwannan@jlu.edu.cn
Publikováno v: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 7, p4062. 27p.
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6
Akademický článek
Integrated use of ligand and structure-based virtual screening, molecular dynamics, free energy calculation and ADME prediction for the identification of potential PTP1B inhibitors.
Autor: Devi B; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (B.H.U.), Varanasi, UP, 221005, India., Vasishta SS; Department of Chemical Engineering & Technology, Indian Institute of Technology (B.H.U.), Varanasi, UP, 221005, India., Das B; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (B.H.U.), Varanasi, UP, 221005, India., Baidya ATK; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (B.H.U.), Varanasi, UP, 221005, India., Rampa RS; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (B.H.U.), Varanasi, UP, 221005, India., Mahapatra MK; Kanak Manjari Institute of Pharmaceutical Sciences, Rourkela, Odisha, 769015, India., Kumar R; Department of Pharmaceutical Engineering & Technology, Indian Institute of Technology (B.H.U.), Varanasi, UP, 221005, India. rajnish.phe@iitbhu.ac.in.
Publikováno v: Molecular diversity [Mol Divers] 2024 Apr; Vol. 28 (2), pp. 649-669. Date of Electronic Publication: 2023 Feb 06.
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7
Akademický článek
INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology.
Autor: Yue EW; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Sparks R; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Polam P; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Modi D; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Douty B; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Wayland B; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Glass B; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Takvorian A; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Glenn J; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Zhu W; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Bower M; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Liu X; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Leffet L; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Wang Q; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Bowman KJ; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Hansbury MJ; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Wei M; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Li Y; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Wynn R; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Burn TC; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Koblish HK; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Fridman JS; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Emm T; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Scherle PA; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Metcalf B; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States., Combs AP; Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, Delaware 19803, United States.
Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2017 Mar 06; Vol. 8 (5), pp. 486-491. Date of Electronic Publication: 2017 Mar 06 (Print Publication: 2017).
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8
Akademický článek
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9
Akademický článek
Recent Studies of Nitrogen and Sulfur Containing Heterocyclic Analogues as Novel Antidiabetic Agents: A Review.
Autor: Gharge S; Department of Pharmaceutical Chemistry, KLE College of Pharmacy, KLE Academy of Higher Education and Research, 590 010, Belagavi, Karnataka, India., Alegaon SG; Department of Pharmaceutical Chemistry, KLE College of Pharmacy, KLE Academy of Higher Education and Research, 590 010, Belagavi, Karnataka, India.
Publikováno v: Chemistry & biodiversity [Chem Biodivers] 2024 Feb; Vol. 21 (2), pp. e202301738. Date of Electronic Publication: 2024 Jan 12.
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10
Akademický článek
N-Arylation of 1,2,4- and 1,3,4-Oxadiazolones under Activated Aromatic Nucleophilic Substitution Conditions.
Autor: Konstantinova, A. S.1,2 (AUTHOR) a.konstantinova@yspu.org, Shetnev, A. A.1 (AUTHOR) a.shetnev@list.ru, Volobueva, A. S.3 (AUTHOR), Korsakov, M. K.2 (AUTHOR)
Publikováno v: Russian Journal of Organic Chemistry. Nov2023, Vol. 59 Issue 11, p1874-1883. 10p.
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