Photoresponsive Adenosine Derivatives for the Optical Control of Adenosine A 2A Receptors in Living Cells.

Autor: Suzuki H; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan., Doura T; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan., Matsuba Y; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan., Matsuoka Y; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan., Araya T; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan., Asada H; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan., Iwata S; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.; RIKEN SPring-8 Center, Kobe, Hyogo 679-5148, Japan., Kiyonaka S; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya 464-8603, Japan.; Research Institute for Quantum and Chemical Innovation, Institutes of Innovation for Future Society, Nagoya University, Nagoya 464-8603, Japan.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2024 Nov 11. Date of Electronic Publication: 2024 Nov 11.

Crystal structure reveals the binding mode and selectivity of a photoswitchable ligand for the adenosine A 2A receptor.

Autor: Araya T; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan., Matsuba Y; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan., Suzuki H; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan., Doura T; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan., Nuemket N; RIKEN SPring-8 Center, Hyogo, 679-5148, Japan; JASRI, Hyogo, 679-5148, Japan., Nango E; RIKEN SPring-8 Center, Hyogo, 679-5148, Japan; Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Miyagi, 980-8577, Japan., Yamamoto M; RIKEN SPring-8 Center, Hyogo, 679-5148, Japan., Im D; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan., Asada H; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan. Electronic address: asada.hidetsugu.4s@kyoto-u.ac.jp., Kiyonaka S; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan; Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University, Nagoya, 464-8603, Japan. Electronic address: kiyonaka@chembio.nagoya-u.ac.jp., Iwata S; Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, 606-8501, Japan; RIKEN SPring-8 Center, Hyogo, 679-5148, Japan. Electronic address: iwata.so.2z@kyoto-u.ac.jp.

Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Feb 05; Vol. 695, pp. 149393. Date of Electronic Publication: 2023 Dec 20.

Coordination chemogenetics for activation of GPCR-type glutamate receptors in brain tissue.

Autor: Ojima K; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan.; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan., Kakegawa W; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan., Yamasaki T; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan., Miura Y; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan., Itoh M; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan., Michibata Y; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan., Kubota R; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan., Doura T; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan., Miura E; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan., Nonaka H; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan., Mizuno S; Laboratory Animal Resource Center in Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, 305-8575, Japan., Takahashi S; Laboratory Animal Resource Center in Transborder Medical Research Center, Faculty of Medicine, University of Tsukuba, Tsukuba, 305-8575, Japan., Yuzaki M; Department of Neurophysiology, Keio University School of Medicine, Tokyo, 160-8582, Japan. myuzaki@keio.jp., Hamachi I; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, 615-8510, Japan. ihamachi@sbchem.kyoto-u.ac.jp., Kiyonaka S; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, 464-8603, Japan. kiyonaka@chembio.nagoya-u.ac.jp.; Institute of Nano-Life-Systems, Institutes of Innovation for Future Society, Nagoya University, Nagoya, 464-8603, Japan. kiyonaka@chembio.nagoya-u.ac.jp.

Publikováno v: Nature communications [Nat Commun] 2022 Jun 16; Vol. 13 (1), pp. 3167. Date of Electronic Publication: 2022 Jun 16.

Orthogonal Activation of Metabotropic Glutamate Receptor Using Coordination Chemogenetics.

Autor: Senoo A; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan., Yamada Y; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan., Ojima K; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan.; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan., Doura T; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan., Hamachi I; Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Kyoto, Japan.; ERATO (Exploratory Research for Advanced Technology, JST), Tokyo, Japan., Kiyonaka S; Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Nagoya, Japan.

Publikováno v: Frontiers in chemistry [Front Chem] 2022 Jan 14; Vol. 9, pp. 825669. Date of Electronic Publication: 2022 Jan 14 (Print Publication: 2021).

Senescence detection using reflected light.

Autor: Dedic, Benjamin¹ (AUTHOR), Westerberg, Leo¹ (AUTHOR), Mosqueda Solís, Andrea^1,2 (AUTHOR), Dumont, Kyle D.³ (AUTHOR), Ruas, Jorge L.^3,4 (AUTHOR), Thorell, Anders⁵ (AUTHOR), Näslund, Erik⁶ (AUTHOR), Spalding, Kirsty L.¹ (AUTHOR) kirsty.spalding@ki.se

Publikováno v: Aging Cell. Nov2024, Vol. 23 Issue 11, p1-15. 15p.