Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Doulaye Dembele"'
Autor:
Caroline Gest, Sandra Sena, Lydia Dif, Véronique Neaud, Robin Loesch, Nathalie Dugot-Senant, Lisa Paysan, Léo Piquet, Terezinha Robbe, Nathalie Allain, Doulaye Dembele, Catherine Guettier, Paulette Bioulac-Sage, Anne Rullier, Brigitte Le Bail, Christophe F. Grosset, Frédéric Saltel, Valérie Lagrée, Sabine Colnot, Violaine Moreau
Publikováno v:
JHEP Reports, Vol 5, Iss 5, Pp 100691- (2023)
Background & Aims: β-catenin is a well-known effector of the Wnt pathway, and a key player in cadherin-mediated cell adhesion. Oncogenic mutations of β-catenin are very frequent in paediatric liver primary tumours. Those mutations are mostly hetero
Externí odkaz:
https://doaj.org/article/842490d9fd564a5d9087b3a228132176
AAV‐delivered diacylglycerol kinase DGKk achieves long‐term rescue of fragile X syndrome mouse model
Autor:
Karima Habbas, Oktay Cakil, Boglárka Zámbó, Ricardos Tabet, Fabrice Riet, Doulaye Dembele, Jean‐Louis Mandel, Michaël Hocquemiller, Ralph Laufer, Françoise Piguet, Hervé Moine
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp 1-15 (2022)
Abstract Fragile X syndrome (FXS) is the most frequent form of familial intellectual disability. FXS results from the lack of the RNA‐binding protein FMRP and is associated with the deregulation of signaling pathways downstream of mGluRI receptors
Externí odkaz:
https://doaj.org/article/f6fe6fea1bab4023b24b4f87b67b8131
Autor:
Ivanka Kamenova, Pooja Mukherjee, Sascha Conic, Florian Mueller, Farrah El-Saafin, Paul Bardot, Jean-Marie Garnier, Doulaye Dembele, Simona Capponi, H. T. Marc Timmers, Stéphane D. Vincent, László Tora
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Genes encoding protein complex subunits are often dispersed in the genome of eukaryotes, raising the question how these protein complexes assemble. Here, the authors provide evidence that mammalian nuclear transcription complexes are formed co-transl
Externí odkaz:
https://doaj.org/article/bbc82790458b46f6b41118387d376ef9
Autor:
Thomas Arbogast, Matthieu Raveau, Claire Chevalier, Valérie Nalesso, Doulaye Dembele, Hugues Jacobs, Olivia Wendling, Michel Roux, Arnaud Duchon, Yann Herault
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 6, Pp 623-634 (2015)
Partial monosomy 21 (PM21) is a rare chromosomal abnormality that is characterized by the loss of a variable segment along human chromosome 21 (Hsa21). The clinical phenotypes of this loss are heterogeneous and range from mild alterations to lethal c
Externí odkaz:
https://doaj.org/article/0c555f6364e54f5bb3de522f49323af9
Autor:
Véronique Brault, Arnaud Duchon, Caroline Romestaing, Ignasi Sahun, Stéphanie Pothion, Mona Karout, Christelle Borel, Doulaye Dembele, Jean-Charles Bizot, Nadia Messaddeq, Andrew J Sharp, Damien Roussel, Stylianos E Antonarakis, Mara Dierssen, Yann Hérault
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005062 (2015)
The trisomy of human chromosome 21 (Hsa21), which causes Down syndrome (DS), is the most common viable human aneuploidy. In contrast to trisomy, the complete monosomy (M21) of Hsa21 is lethal, and only partial monosomy or mosaic monosomy of Hsa21 is
Externí odkaz:
https://doaj.org/article/b40c51e2932f4ffab25edd46f6fc0748
Autor:
Sarina Ravens, Marjorie Fournier, Tao Ye, Matthieu Stierle, Doulaye Dembele, Virginie Chavant, Làszlò Tora
Publikováno v:
eLife, Vol 3 (2014)
The histone acetyltransferase (HAT) Mof is essential for mouse embryonic stem cell (mESC) pluripotency and early development. Mof is the enzymatic subunit of two different HAT complexes, MSL and NSL. The individual contribution of MSL and NSL to tran
Externí odkaz:
https://doaj.org/article/50aa5cc9a3c043beaeed83a4d7e20fc9
Autor:
Matthieu Raveau, Jacques M Lignon, Valérie Nalesso, Arnaud Duchon, Yoram Groner, Andrew J Sharp, Doulaye Dembele, Véronique Brault, Yann Hérault
Publikováno v:
PLoS Genetics, Vol 8, Iss 5, p e1002724 (2012)
Down syndrome (DS) leads to complex phenotypes and is the main genetic cause of birth defects and heart diseases. The Ts65Dn DS mouse model is trisomic for the distal part of mouse chromosome 16 and displays similar features with post-natal lethality
Externí odkaz:
https://doaj.org/article/51f56e59e5ff439ba64d46c309343654
Autor:
Jean-Claude Garaud, Jean-Nicolas Schickel, Gilles Blaison, Anne-Marie Knapp, Doulaye Dembele, Julie Ruer-Laventie, Anne-Sophie Korganow, Thierry Martin, Pauline Soulas-Sprauel, Jean-Louis Pasquali
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23900 (2011)
Systemic lupus erythematosous (SLE) is an autoimmune disease with an important clinical and biological heterogeneity. B lymphocytes appear central to the development of SLE which is characterized by the production of a large variety of autoantibodies
Externí odkaz:
https://doaj.org/article/5df10ee521d74432b3708ce21b5fdc0b
Publikováno v:
African Journal of Agricultural Research. 14:1335-1340
The development of market gardening is faced with many problems among which there are the nematodes of the genus Meloidogyne. The aim of this study is twofold: (a) determining the Meloidogyne species that are crowned by the perineal plates of female
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8369a4cb4122ae1f28f52fb08a81f376
https://doi.org/10.5897/ajar2019.14038
https://doi.org/10.5897/ajar2019.14038
Autor:
Nassim Dali‐Youcef, Michel Vix, Federico Costantino, Houssein El‐Saghire, Benoit Lhermitte, Cosimo Callari, Jacopo D’Agostino, Silvana Perretta, Stefan Paveliu, Monica Gualtierotti, Edith Dumeny, Marine A. Oudot, Amélie Jaulin, Doulaye Dembélé, Mirjam B. Zeisel, Catherine Tomasetto, Thomas F. Baumert, Michel Doffoël
Publikováno v:
Hepatology Communications, Vol 3, Iss 9, Pp 1205-1220 (2019)
Nonalcoholic fatty liver disease (NAFLD) is a metabolic disorder due to increased accumulation of fat in the liver and in many cases to enhanced inflammation. Although the contribution of inflammation in the pathogenesis of NAFLD is well established,
Externí odkaz:
https://doaj.org/article/5c47567d5a5f4bdea27e87f48d9dd20c