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pro vyhledávání: '"Douglas W. Raiford"'
Autor:
Dan E. Krane, Douglas W. Raiford, Esley M. Heizer, Michael L. Raymer, Travis E. Doom, Robert V. Miller
Publikováno v:
Journal of Molecular Evolution. 74:206-216
Metabolic efficiency, as a selective force shaping proteomes, has been shown to exist in Escherichia coli and Bacillus subtilis and in a small number of organisms with photoautotrophic and thermophilic lifestyles. Earlier attempts at larger-scale ana
Autor:
Douglas W. Raiford, Hiroshi Akashi, Dan E. Krane, Esley M. Heizer, Michael L. Raymer, Robert V. Miller
Publikováno v:
Journal of Molecular Evolution. 67:621-630
Prokaryotic organisms preferentially utilize less energetically costly amino acids in highly expressed genes. Studies have shown that the proteome of Saccharomyces cerevisiae also exhibits this behavior, but only in broad terms. This study examines t
Autor:
Jean-Marc Lanchy, J. Stephen Lodmell, Douglas W. Raiford, Mary Ellenbecker, Alec Sundet, Jeremy St. Goddard
Publikováno v:
Computational biology and chemistry. 58
Display Omitted A family of RNA aptamers selected for their ability to bind to a viral protein, but whose secondary structures were uncharacterized, was folded and numerically scored in silico.The predicted structural characteristics of randomly gene
Autor:
Robert V. Miller, Michael L. Raymer, Douglas W. Raiford, Dan E. Krane, Esley M. Heizer, Travis E. Doom
Publikováno v:
Molecular Biology and Evolution. 23:1670-1680
For most prokaryotic organisms, amino acid biosynthesis represents a significant portion of their overall energy budget. The difference in the cost of synthesis between amino acids can be striking, differing by as much as 7-fold. Two prokaryotic orga
Halophilic archaea accumulate molar concentrations of KCl in their cytoplasm as an osmoprotectant and have evolved highly acidic proteomes that function only at high salinity. We examined osmoprotection in the photosynthetic Proteobacteria Halorhodos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6633323b3b414764d11f580d02762ef0
https://europepmc.org/articles/PMC3537055/
https://europepmc.org/articles/PMC3537055/
Publikováno v:
IEEE/ACM transactions on computational biology and bioinformatics. 8(2)
The study of codon usage bias is an important research area that contributes to our understanding of molecular evolution, phylogenetic relationships, respiratory lifestyle, and other characteristics. Translational efficiency bias is perhaps the most
Publikováno v:
Bioinformatics (Oxford, England). 26(18)
Motivation: As next generation sequencing is rapidly adding new genomes, their correct placement in the taxonomy needs verification. However, the current methods for confirming classification of a taxon or suggesting revision for a potential misplace
Publikováno v:
IEEE/ACM transactions on computational biology and bioinformatics. 7(2)
Genomic sequencing projects are an abundant source of information for biological studies ranging from the molecular to the ecological in scale; however, much of the information present may yet be hidden from casual analysis. One such information doma
Publikováno v:
CIBCB
Phylogenetic tree analysis using molecular sequences continues to expand beyond the 16S rRNA marker. By addressing the multi-copy issue known as the intra-heterogeneity, this paper restores the focus in using the 16S rRNA marker. Through use of a nov
Publikováno v:
2009 Ohio Collaborative Conference on Bioinformatics.
Amino acid biosynthetic pathways are highly conserved throughout all domains of life. Biosynthesis of amino acid requires the diversion of resources from energy production to amino acid production. The consequent energy-cost of producing an individua