Zobrazeno 1 - 10 of 11 pro vyhledávání: '"Douglas W. Piper"'
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A Comparative Overview of the Adverse Effects of Antiulcer Drugs
Autor: Douglas W. Piper
Publikováno v: Drug Safety. 12:120-138
During the past 2 decades, great advances have been made in the treatment of ulcer disease. This has involved the development of new drugs that are not only well tolerated, but are relatively inexpensive. The lack of significant adverse effects has r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cdb79b1421fdf75e766b8d4fc03a83
https://doi.org/10.2165/00002018-199512020-00005
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3
Lipid peroxidation in the adrenal glands of male rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
Autor: Walter N. Piper, Lorelle L. Bestervelt, Jeff A. Pitt, Douglas W. Piper
Publikováno v: Toxicology Letters. 70:139-145
This study was performed to determine whether TCDD (50 μg kg ; single oral dose) could induce adrenal microsomal lipid peroxidation, which might be correlated to decreased levels of cytochrome P-450 and 21-hydroxylase activity. The amount of malondi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7811400a48927b6c978b4ef5de9e1c17
https://doi.org/10.1016/0378-4274(94)90157-0
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4
TCDD alters pituitary-adrenal function I: Adrenal responsiveness to exogenous ACTH
Autor: Walter N. Piper, Douglas W. Piper, Yong Cai, Jeff A. Pitt, Colleen J. Nolan, Lorelle L. Bestervelt
Publikováno v: Neurotoxicology and Teratology. 15:365-370
Plasma ACTH concentrations in 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats (50 micrograms/kg; single, oral dose) were 2.1-, 2.1-, 2.9-, 1.7-, 1.5-, 2.0- and 3.0-fold greater than control values, respectively, at days 1, 3, 5, 7, 10, and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9747d90387f2adfd9cd84c83ddf94d39
https://doi.org/10.1016/0892-0362(93)90052-p
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5
In vitro 2,3,7,8-tetrachlorodibenzo-p-dioxin interference with the anterior pituitary hormone adrenocorticortropin
Autor: Lorelle L. Bestervelt, Joseph A. Dybowski, Walter N. Piper, Gerald A. Dayharsh, Jeff A. Pitt, Yong Cai, Douglas W. Piper, Colleen J. Nolan
Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology. 44(2)
Treatment of male Sprague-Dawley rats with a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has been shown to increase serum adrenocorticotropin (ACTH) and decrease serum corticosterone. The present in vitro study was designed to asse
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9242a13e7cf7ae014d88461658bc095b
https://pubmed.ncbi.nlm.nih.gov/9742651
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7
Effect of omeprazole and ranitidine on ulcer healing and relapse rates in patients with benign gastric ulcer
Autor: Meinhard Classen, Sven Eriksson, Cornelis B.H.W. Lamers, Douglas W. Piper, Kerstin Rutgersson, Anders Walan, Jean-Pierre Bader
Publikováno v: The New England journal of medicine. 320(2)
Omeprazole blocks the action of H+,K+-ATPase in the gastric mucosa and thus inhibits the secretion of hydrochloric acid. We conducted a double-blind multicenter study (45 centers in 13 countries) of 602 patients with benign gastric or prepyloric ulce
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a226f125e878701dc56860adae823df
https://pubmed.ncbi.nlm.nih.gov/2747753
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