Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Douglas W. Grosenbach"'
Autor:
Todd M. Bell, Paul Facemire, Jeremy J. Bearss, Jo Lynne Raymond, Jennifer Chapman, Xiankun Zeng, Joshua D. Shamblin, Janice A. Williams, Douglas W. Grosenbach, Dennis E. Hruby, Inger K. Damon, Arthur J. Goff, Eric M. Mucker
Publikováno v:
PLoS Pathogens, Vol 20, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/cf1b45fcdc1249ea92434623b67e6cd7
Publikováno v:
Expert Review of Anti-infective Therapy. 21:235-242
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f03bb20a6c35ed142847acf99ab0116
https://doi.org/10.1080/14787210.2023.2170350
https://doi.org/10.1080/14787210.2023.2170350
Autor:
Gaëlle Frenois-Veyrat, Franck Gallardo, Olivier Gorgé, Elie Marcheteau, Olivier Ferraris, Artem Baidaliuk, Anne-Laure Favier, Cécile Enfroy, Xavier Holy, Jérémy Lourenco, Rhéa Khoury, Flora Nolent, Douglas W. Grosenbach, Dennis Hruby, Audrey Ferrier, Frédéric Iseni, Etienne Simon-Loriere, Jean-Nicolas Tournier
The ongoing monkeypox virus (MPXV) outbreak is the largest ever recorded outside of Africa. Genomic analysis revealed a divergent phylogenetic lineage within clade 3, and atypical clinical presentations have been noted. We report the sequencing and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e5984fac9cbea9581a4bc8745ea074
https://hal-pasteur.archives-ouvertes.fr/pasteur-04036302/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-04036302/document
Autor:
Gaëlle Frenois-Veyrat, Franck Gallardo, Olivier Gorgé, Elie Marcheteau, Olivier Ferraris, Artem Baidaliuk, Anne-Laure Favier, Cécile Enfroy, Xavier Holy, Jérémy Lourenco, Rhéa Khoury, Flora Nolent, Douglas W. Grosenbach, Dennis E. Hruby, Audrey Ferrier, Frédéric Iseni, Etienne Simon-Loriere, Jean-Nicolas Tournier
Publikováno v:
Nature microbiology. 7(12)
The ongoing monkeypox virus (MPXV) outbreak is the largest ever recorded outside of Africa. We isolated and sequenced a virus from the first clinical MPXV case diagnosed in France (May 2022). We report that tecovirimat (ST-246), a US Food and Drug Ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb5665a4d1ab240871608861f4feca3
https://pubmed.ncbi.nlm.nih.gov/36344621
https://pubmed.ncbi.nlm.nih.gov/36344621
Autor:
Douglas W. Grosenbach, Paul G Long, Dennis E. Hruby, Andrew T. Russo, Candace Lovejoy, Ingrid Meara, Biswajit Maiti, Kady M. Honeychurch, Jarasvech Chinsangaram
Publikováno v:
Expert Review of Anti-infective Therapy. 19:331-344
Tecovirimat (TPOXX®; ST-246) was approved for the treatment of symptomatic smallpox by the USFDA in July of 2018 and has been stockpiled by the US government for use in a smallpox outbreak. While there has not been a reported case of smallpox since
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03dc2def56381c858bab7f5fa34ac3a6
https://doi.org/10.1080/14787210.2020.1819791
https://doi.org/10.1080/14787210.2020.1819791
Autor:
Catherine B. Bigger, Andrew T. Russo, Aklile Berhanu, Dennis E. Hruby, Jon Prigge, Douglas W. Grosenbach, Peter Silvera
Publikováno v:
Vaccine
Naturally occurring smallpox has been eradicated but research stocks of variola virus (VARV), the causative agent of smallpox, still exist in secure laboratories. Clandestine stores of the virus or resurrection of VARV via synthetic biology are possi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3e432571b3c73936f835d82b13ce7c
https://doi.org/10.1016/j.vaccine.2019.10.049
https://doi.org/10.1016/j.vaccine.2019.10.049
Autor:
Douglas W. Grosenbach, Trevor Brasel, Andrew G Cawthon, Philip J. Kuehl, Erin S. Reynolds, Dennis E. Hruby, Robert O Baker, Andrew T Russo, Victoria Sugita, Tara Bailey, Krystle N. Agans
Publikováno v:
The Journal of Infectious Diseases. 218:1490-1499
Background Tecovirimat (ST-246) is being developed as an antiviral therapeutic for smallpox for use in the event of an accidental or intentional release. The last reported case of smallpox was 1978 but the potential for use of variola virus for biowa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c44eb1eee7a317b0863bf927427ff4
https://doi.org/10.1093/infdis/jiy326
https://doi.org/10.1093/infdis/jiy326
Autor:
Douglas W, Grosenbach, Dennis E, Hruby
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2023
The lack of antiviral drugs for the treatment of orthopoxvirus disease represents an unmet medical need, particularly due to the threat of variola virus (the causative agent of smallpox) as an agent of biowarfare or bioterrorism (Henderson, 283:1279-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d4f35ed2dff28aaee891043481c3c26
https://pubmed.ncbi.nlm.nih.gov/31240676
https://pubmed.ncbi.nlm.nih.gov/31240676
Autor:
Dennis E. Hruby, Douglas W. Grosenbach
Publikováno v:
Methods in Molecular Biology ISBN: 9781493995929
The lack of antiviral drugs for the treatment of orthopoxvirus disease represents an unmet medical need, particularly due to the threat of variola virus (the causative agent of smallpox) as an agent of biowarfare or bioterrorism (Henderson, 283:1279-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d9872c1f9821f73c434d92ffdc56b4
https://doi.org/10.1007/978-1-4939-9593-6_9
https://doi.org/10.1007/978-1-4939-9593-6_9
Autor:
Dennis E. Hruby, Paul G Long, Jarasvech Chinsangaram, Annie Frimm, Candace Lovejoy, Biswajit Maiti, Eric A. Rose, Ingrid Meara, Kady M. Honeychurch, Douglas W. Grosenbach
Publikováno v:
The New England journal of medicine
Smallpox was declared eradicated in 1980, but variola virus (VARV), which causes smallpox, still exists. There is no known effective treatment for smallpox; therefore, tecovirimat is being developed as an oral smallpox therapy. Because clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfebb26a63f3288d5bbc8826fcabdf7f
https://hdl.handle.net/10067/1714920151162165141
https://hdl.handle.net/10067/1714920151162165141