Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Douglas W. Bjelland"'
Autor:
Emma C Johnson, Douglas W Bjelland, Daniel P Howrigan, Abdel Abdellaoui, Gerome Breen, Anders Borglum, Sven Cichon, Franziska Degenhardt, Andreas J Forstner, Josef Frank, Giulio Genovese, Stefanie Heilmann-Heimbach, Stefan Herms, Per Hoffman, Wolfgang Maier, Manuel Mattheisen, Derek Morris, Bryan Mowry, Betram Müller-Mhysok, Benjamin Neale, Igor Nenadic, Markus M Nöthen, Colm O'Dushlaine, Marcella Rietschel, Douglas M Ruderfer, Dan Rujescu, Thomas G Schulze, Matthew A Simonson, Eli Stahl, Jana Strohmaier, Stephanie H Witt, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Patrick F Sullivan, Matthew C Keller
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006343 (2016)
It is well known that inbreeding increases the risk of recessive monogenic diseases, but it is less certain whether it contributes to the etiology of complex diseases such as schizophrenia. One way to estimate the effects of inbreeding is to examine
Externí odkaz:
https://doaj.org/article/73b4778def244d36875bdb4d8766b236
Autor:
Luke M. Evans, Michael E. Goddard, Rasool Tahmasbi, Sayantan Das, Douglas W. Bjelland, Gonçalo R. Abecasis, Scott I. Vrieze, Jian Yang, Matthew C. Keller, Teresa R de Candia, Peter M. Visscher, Benjamin M. Neale, Steven Gazal
Publikováno v:
Nature genetics
Multiple methods have been developed to estimate narrow-sense heritability, h2, using single nucleotide polymorphisms (SNPs) in unrelated individuals. However, a comprehensive evaluation of these methods has not yet been performed, leading to confusi
Autor:
Matthew C. Keller, Teresa R de Candia, Luke M. Evans, Sayantan Das, Gonçalo R. Abecasis, Michael E. Goddard, Douglas W. Bjelland, Benjamin M. Neale, Scott I. Vrieze, Peter M. Visscher, Jian Yang, Rasool Tahmasbi
Heritability, h2, is a foundational concept in genetics, critical to understanding the genetic basis of complex traits. Recently-developed methods that estimate heritability from genotyped SNPs, h2SNP, explain substantially more genetic variance than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe25115765809a68e524b73e5cfe55a
Publikováno v:
Journal of Dairy Science. 96:4697-4706
The effects of increased pedigree inbreeding in dairy cattle populations have been well documented and result in a negative impact on profitability. Recent advances in genotyping technology have allowed researchers to move beyond pedigree analysis an
Identical by descent (IBD) segments are used to understand a number of fundamental issues in genetics. IBD segments are typically detected using long stretches of identical alleles between haplotypes in whole-genome SNP data. Phase or SNP call errors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6f9c4e36a78f92432e6b373d103b87
Publikováno v:
Journal of dairy science. 98(7)
Recent evidence has suggested that some of the decline in reproductive ability in dairy cattle has been caused by embryonic death. The current study compared expected genomic inbreeding from sire–dam mating pairs to genomic inbreeding from live pro
Publikováno v:
Journal of dairy science. 94(12)
The phosphorus requirements for dairy heifers (0.20-0.35%) and endogenous concentrations (0.20-35%) of P in feeds fed to dairy heifers are similar, suggesting that the need for supplemental P in dairy heifer diets may be minimal. Because long-term P
Publikováno v:
Journal of dairy science. 94(10)
A total of 648 purebred Holstein and 319 backcross Holstein × Jersey dairy cattle were compared for production, reproduction, health, linear type, and growth traits. Animals were born between 2003 and 2009 and were housed in the University of Wiscon