Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Douglas V Dolfi"'
Autor:
Douglas V Dolfi, Kathleen D Mansfield, Raj K Kurupati, Senthil Kannan, Susan A Doyle, Hildegund C J Ertl, Kenneth E Schmader, E John Wherry
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77164 (2013)
Current yearly influenza virus vaccines induce strain-specific neutralizing antibody (NAb) responses providing protective immunity to closely matched viruses. However, these vaccines are often poorly effective in high-risk groups such as the elderly
Externí odkaz:
https://doaj.org/article/f6e91471e32d431baab54f6c858f932d
Autor:
Steven M. Albelda, E. John Wherry, James L. Riley, Carl H. June, Michael C. Milone, Ellen Puré, John Scholler, Veena Kapoor, Jing Sun, Raghuveer Ranganathan, Caleph B. Wilson, Douglas V. Dolfi, Liang-Chuan Wang, Edmund K. Moon
PDF file - 38K, CAR TILs upregulate inhibitory receptors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f79c4a1b0c205d2b72b570f22c04268
https://doi.org/10.1158/1078-0432.22447659
https://doi.org/10.1158/1078-0432.22447659
Autor:
Steven M. Albelda, E. John Wherry, James L. Riley, Carl H. June, Michael C. Milone, Ellen Puré, John Scholler, Veena Kapoor, Jing Sun, Raghuveer Ranganathan, Caleph B. Wilson, Douglas V. Dolfi, Liang-Chuan Wang, Edmund K. Moon
Purpose: Immunotherapy using vaccines or adoptively transferred tumor-infiltrating lymphocytes (TIL) is limited by T-cell functional inactivation within the solid tumor microenvironment. The purpose of this study was to determine whether a similar tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b98fdf2979d99f74586fddc8a1cf52
https://doi.org/10.1158/1078-0432.c.6521160
https://doi.org/10.1158/1078-0432.c.6521160
Autor:
Steven M. Albelda, E. John Wherry, James L. Riley, Carl H. June, Michael C. Milone, Ellen Puré, John Scholler, Veena Kapoor, Jing Sun, Raghuveer Ranganathan, Caleph B. Wilson, Douglas V. Dolfi, Liang-Chuan Wang, Edmund K. Moon
PDF file - 74K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52558bab621f35fc0323933d1873ec22
https://doi.org/10.1158/1078-0432.22447662
https://doi.org/10.1158/1078-0432.22447662
Autor:
Steven M. Albelda, E. John Wherry, James L. Riley, Carl H. June, Michael C. Milone, Ellen Puré, John Scholler, Veena Kapoor, Jing Sun, Raghuveer Ranganathan, Caleph B. Wilson, Douglas V. Dolfi, Liang-Chuan Wang, Edmund K. Moon
PDF file - 37K, CAR spleen infiltrating lymphocytes have lower levels of inhibitory receptors than CAR tumor infiltrating lymphocytes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1374a7136eb7fc88c54352c2447e0315
https://doi.org/10.1158/1078-0432.22447653
https://doi.org/10.1158/1078-0432.22447653
Autor:
Steven M. Albelda, E. John Wherry, James L. Riley, Carl H. June, Michael C. Milone, Ellen Puré, John Scholler, Veena Kapoor, Jing Sun, Raghuveer Ranganathan, Caleph B. Wilson, Douglas V. Dolfi, Liang-Chuan Wang, Edmund K. Moon
PDF file - 756K, Supplemental Fig 1. EMP and EMMESO mesothelin expression. Supplemental Fig 2. EMMESO flank tumors retain antigen expression in vivo. Supplemental Fig 3. MesoCAR TILs are unable to secrete IL-2 in response to antigen. Supplemental Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142119cc41b5d78ad6cfb101a40dbb6f
https://doi.org/10.1158/1078-0432.22447665.v1
https://doi.org/10.1158/1078-0432.22447665.v1
Autor:
Sarah E. Henrickson, Elizabeth R. Alpern, Rakesh D. Mistry, Kathleen E. Sullivan, Scott E. Hensley, E. John Wherry, Sasikanth Manne, Susan E. Coffin, Kathleen D. Mansfield, Douglas V. Dolfi, Kaela Parkhouse
Publikováno v:
Cell Reports, Vol 22, Iss 2, Pp 411-426 (2018)
Summary: Acute respiratory tract viral infections (ARTIs) cause significant morbidity and mortality. CD8 T cells are fundamental to host responses, but transcriptional alterations underlying anti-viral mechanisms and links to clinical characteristics
Autor:
Kenneth E. Schmader, E. John Wherry, Morgan A. Reuter, S. Kannan, Osama Z. Badwan, David H. Canaday, Douglas V. Dolfi, Michael R. Betts, Htin Aung, Raj K. Kurupati, Ramin S. Herati, Hildegund C.J. Ertl, Kathleen D. Mansfield
Publikováno v:
The Journal of Immunology. 193:3528-3537
Although influenza vaccination is recommended for all adults annually, the incidence of vaccine failure, defined as weak or absent increase in neutralizing Ab titers, is increased in the elderly compared with young adults. The T follicular helper cel
Autor:
Michael C. Milone, Caleph B. Wilson, Liang-Chuan Wang, Steven M. Albelda, Raghuveer Ranganathan, Douglas V. Dolfi, Ellen Puré, Jing Sun, Veena Kapoor, Edmund K. Moon, Carl H. June, E. John Wherry, James L. Riley, John Scholler
Publikováno v:
Clinical Cancer Research. 20:4262-4273
Purpose: Immunotherapy using vaccines or adoptively transferred tumor-infiltrating lymphocytes (TIL) is limited by T-cell functional inactivation within the solid tumor microenvironment. The purpose of this study was to determine whether a similar tu