Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Douglas S. Lyles"'
Autor:
Teddy E. Kim, Shelby Puckett, Kailong Zhang, Denise M. Herpai, David A. Ornelles, John N. Davis, Anthony N. van den Pol, Waldemar Debinski, Douglas S. Lyles
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 232-244 (2021)
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using establishe
Externí odkaz:
https://doaj.org/article/2b342b9766dc49d78a5a680f8de8cf26
Autor:
Robert S. Bayne, Shelby Puckett, Lindsey Ulkus Rodrigues, Scott D. Cramer, Jingyun Lee, Cristina M. Furdui, Jeff W. Chou, Lance D. Miller, David A. Ornelles, Douglas S. Lyles
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 496-507 (2020)
A key principle of oncolytic viral therapy is that many cancers develop defects in their antiviral responses, making them more susceptible to virus infection. However, some cancers display resistance to viral infection. Many of these resistant cancer
Externí odkaz:
https://doaj.org/article/64f82ffa6e0f4fe8b1639c233c80cf25
Autor:
Douglas S. Lyles
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 433- (2021)
Externí odkaz:
https://doaj.org/article/cdfade5d511b472b8301b20048025a8c
Autor:
Nisha Asok Kumar, Sreenath Muraleedharan Suma, Umerali Kunnakkadan, Joydeep Nag, Reshma Koolaparambil Mukesh, Douglas S. Lyles, John Bernet Johnson
Publikováno v:
Viruses, Vol 13, Iss 3, p 373 (2021)
The human complement system is an important part of the innate immune system. Its effector pathways largely mediate virus neutralization. Vesicular stomatitis virus (VSV) activates the classical pathway of the complement, leading to virus neutralizat
Externí odkaz:
https://doaj.org/article/ccbc9812e81548e9b4d061dbd4072012
Publikováno v:
Vaccines, Vol 6, Iss 1, p 16 (2018)
Recombinant vesicular stomatitis virus (VSV) is a promising platform for vaccine development. M51R VSV, an attenuated, M protein mutant strain, is an effective inducer of Type I interferon and dendritic cell (DC) maturation, which are desirable prope
Externí odkaz:
https://doaj.org/article/537fe82536104415877ff3f27c33f686
Publikováno v:
Viruses, Vol 1, Iss 3, Pp 832-851 (2009)
Like many animal viruses, those of the Rhabdoviridae family, are able to antagonize the type I interferon response and cause disease in mammalian hosts. Though these negative-stranded RNA viruses are very simple and code for as few as five proteins,
Externí odkaz:
https://doaj.org/article/982f0222eccf4e1a881436d957eca172
Autor:
Shelby Puckett, Douglas S. Lyles, Teddy E. Kim, Anthony N. van den Pol, David A. Ornelles, John N. Davis, Denise Herpai, Waldemar Debinski, Kailong Zhang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss, Pp 232-244 (2021)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c98392e0f636d8e890d1df993fa577
http://www.sciencedirect.com/science/article/pii/S2372770521000826
http://www.sciencedirect.com/science/article/pii/S2372770521000826
Autor:
Steven J. Moran, Shelby Puckett, David A. Ornelles, Jed C. Macosko, George Holzwarth, Douglas S. Lyles
Publikováno v:
J Virol
A recently developed variational Bayesian analysis using pattern recognition and machine learning of single viral ribonucleoprotein (RNP) particle tracks in the cytoplasm of living cells provides a quantitative molecular explanation for active diffus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e616ea3134403d0bbd43cd1d2ee74297
https://europepmc.org/articles/PMC9555154/
https://europepmc.org/articles/PMC9555154/
Autor:
Shelby Puckett, Douglas S. Lyles, Jingyun Lee, Scott D. Cramer, Robert S. Bayne, Cristina M. Furdui, Jeff W. Chou, David A. Ornelles, Lance D. Miller, Lindsey Ulkus Rodrigues
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss, Pp 496-507 (2020)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
A key principle of oncolytic viral therapy is that many cancers develop defects in their antiviral responses, making them more susceptible to virus infection. However, some cancers display resistance to viral infection. Many of these resistant cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84113db0793aef220f0b232902c3cc4
https://doi.org/10.1016/j.omto.2020.05.004
https://doi.org/10.1016/j.omto.2020.05.004
Publikováno v:
Curr Opin Nephrol Hypertens
Purpose of review The presence of viruses in urine (urine virome) typically reflects infection in the kidneys and urinary tract. The urinary virome is associated with HIV-associated nephropathy and chronic glomerulosclerosis. There are many associati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55229b20347e1b7b22a15169b738011c
https://doi.org/10.1097/mnh.0000000000000464
https://doi.org/10.1097/mnh.0000000000000464