Zobrazeno 1 - 10
of 238
pro vyhledávání: '"Douglas S. Goodin"'
Autor:
Douglas S. Goodin, Jorge R. Oksenberg, Venceslas Douillard, Pierre-Antoine Gourraud, Nicolas Vince
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Objective To explore the nature of genetic-susceptibility to multiple sclerosis (MS) in African-Americans. Background Recently, the number of genetic-associations with MS has exploded although the MS-associations of specific haplotypes within the maj
Externí odkaz:
https://doaj.org/article/4f7643d48d8340ca89c6f42189c41eea
Autor:
Douglas S. Goodin
Multiple Sclerosis (MS) is generally understood to be an inflammatory autoimmune disease of the central nervous system. While we still are not certain of the root cause of MS, research results suggest that unknown environmental factors and the presen
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0190043 (2018)
To determine the relationship between highly-conserved extended-haplotypes (CEHs) in the major histocompatibility complex (MHC) and MS-susceptibility.Among the ~200 MS-susceptibility regions, which are known from genome-wide analyses of single nucleo
Externí odkaz:
https://doaj.org/article/144c7b22a59c447abbcd2feda5f770da
Autor:
Riley Bove, Shane Poole, Richard Cuneo, Sasha Gupta, Joseph Sabatino, Meagan Harms, Tifffany Cooper, William Rowles, Nicolette Miller, Refujia Gomez, Robin Lincoln, Kira McPolin, Kyra Powers, Adam Santaniello, Adam Renschen, Carolyn J. Bevan, Jeffrey M. Gelfand, Douglas S. Goodin, Chu-Yueh Guo, Andrew R. Romeo, Stephen L. Hauser, Bruce Anthony Campbell Cree
Publikováno v:
Neurology(R) neuroimmunologyneuroinflammation. 10(2)
Background and ObjectivesProspective, deeply phenotyped research cohorts monitoring individuals with chronic neurologic conditions, such as multiple sclerosis (MS), depend on continued participant engagement. The COVID-19 pandemic restricted in-clini
Autor:
Antje, Bischof, Nico, Papinutto, Anisha, Keshavan, Anand, Rajesh, Gina, Kirkish, Xinheng, Zhang, Jacob M, Mallott, Carlo, Asteggiano, Simone, Sacco, Tristan J, Gundel, Chao, Zhao, William A, Stern, Eduardo, Caverzasi, Yifan, Zhou, Refujia, Gomez, Nicholas R, Ragan, Adam, Santaniello, Alyssa H, Zhu, Jeremy, Juwono, Carolyn J, Bevan, Riley M, Bove, Elizabeth, Crabtree, Jeffrey M, Gelfand, Douglas S, Goodin, Jennifer S, Graves, Ari J, Green, Jorge R, Oksenberg, Emmanuelle, Waubant, Michael R, Wilson, Scott S, Zamvil, Bruce A C, Cree, Stephen L, Hauser, Roland G, Henry
Publikováno v:
Annals of neurology. 91(2)
A major challenge in multiple sclerosis (MS) research is the understanding of silent progression and Progressive MS. Using a novel method to accurately capture upper cervical cord area from legacy brain MRI scans we aimed to study the role of spinal
An electronic, unsupervised patient-reported Expanded Disability Status Scale for multiple sclerosis
Autor:
Andrew R Romeo, Stephen L. Hauser, Erica Schleimer, Refujia Gomez, J B Jones, Patrick Barba, William Rowles, Wan-Yu Hsu, Chao Zhao, Adam Santaniello, Riley Bove, Jeffrey M. Gelfand, Walter F. Stewart, Douglas S. Goodin, Jennifer R. Pearce, Bruce A.C. Cree
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England), vol 27, iss 9
Mult Scler
Mult Scler
Background: In persons with multiple sclerosis (MS), the Expanded Disability Status Scale (EDSS) is the criterion standard for assessing disability, but its in-person nature constrains patient participation in research and clinical assessments. Objec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04a662b71696b5a9ddf1f3e77e7888e
https://escholarship.org/uc/item/6d45b620
https://escholarship.org/uc/item/6d45b620
Publikováno v:
BMC medical genomics, vol 14, iss 1
BMC Medical Genomics
BMC Medical Genomics, BioMed Central, 2021, 14 (1), pp.183. ⟨10.1186/s12920-021-01018-6⟩
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-15 (2021)
BMC Medical Genomics, 2021, 14 (1), pp.183. ⟨10.1186/s12920-021-01018-6⟩
BMC Medical Genomics
BMC Medical Genomics, BioMed Central, 2021, 14 (1), pp.183. ⟨10.1186/s12920-021-01018-6⟩
BMC Medical Genomics, Vol 14, Iss 1, Pp 1-15 (2021)
BMC Medical Genomics, 2021, 14 (1), pp.183. ⟨10.1186/s12920-021-01018-6⟩
OBJECTIVETo study the accumulation of MS-risk resulting from different combinations of MS-associated conserved-extended-haplotypes of the MHC and three non-MHC risk-loci nearby genes EOMES, ZFP36L1, CLEC16A.BACKGROUNDDefining “genetic-susceptibilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed882f6a10cfddd4abcf5363ff8e33e
https://escholarship.org/uc/item/5ct6j367
https://escholarship.org/uc/item/5ct6j367
Autor:
Gina Kirkish, Jorge R. Oksenberg, Alyssa H. Zhu, Jill A. Hollenbach, Ari J. Green, Nicholas R Ragan, Jeffrey M. Gelfand, Patrick Barba, Roland G. Henry, Stephen L. Hauser, Simone Sacco, Gillian Rush, Scott S. Zamvil, Antje Bischof, Adam Santaniello, Douglas S. Goodin, Michael R. Wilson, Refujia Gomez, Tristan Gundel, Sergio E. Baranzini, Andrew R Romeo, Chao Zhao, Bruce A.C. Cree, Eduardo Caverzasi, Jennifer Graves, Nico Papinutto, Riley Bove, William A. Stern, Carolyn Bevan
Publikováno v:
Annals of Neurology
Author(s): University of California, San Francisco MS-EPIC Team; Cree, Bruce AC; Hollenbach, Jill A; Bove, Riley; Kirkish, Gina; Sacco, Simone; Caverzasi, Eduardo; Bischof, Antje; Gundel, Tristan; Zhu, Alyssa H; Papinutto, Nico; Stern, William A; Bev
Autor:
Douglas S Goodin, Pouya Khankhanian
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e90034 (2014)
BACKGROUND: Genome-wide association studies (GWAS) identify disease-associations for single-nucleotide-polymorphisms (SNPs) from scattered genomic-locations. However, SNPs frequently reside on several different SNP-haplotypes, only some of which may
Externí odkaz:
https://doaj.org/article/2e6de6119c0e4a569cb535dbfb79724a
Autor:
Douglas S Goodin, Michael Corwin, David Kaufman, Howard Golub, Shoshana Reshef, Mark J Rametta, Volker Knappertz, Gary Cutter, Dirk Pleimes
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105207 (2014)
BACKGROUND: Information on causes of death (CODs) for patients with multiple sclerosis (MS) in the United States is sparse and limited by standard categorizations of underlying and immediate CODs on death certificates. Prior research indicated that e
Externí odkaz:
https://doaj.org/article/a17a44abb9524be3a7e06eda0eb690a9