Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Douglas S Rehder"'
Autor:
Paul E Oran, Olgica Trenchevska, Dobrin Nedelkov, Chad R Borges, Matthew R Schaab, Douglas S Rehder, Jason W Jarvis, Nisha D Sherma, Luhui Shen, Bryan Krastins, Dawn C Schwenke, Peter D Reaven, Randall W Nelson
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92801 (2014)
Insulin-like growth factor 1 (IGF1) is an important biomarker for the management of growth hormone disorders. Recently there has been rising interest in deploying mass spectrometric (MS) methods of detection for measuring IGF1. However, widespread cl
Externí odkaz:
https://doaj.org/article/bb85b97f782f4818917849d3347eec55
Autor:
Diya Ren, Dengfeng Liu, Chris J. Wisniewski, Douglas S. Rehder, Matthew R. Schenauer, Dell Farnan
Publikováno v:
mAbs. 11:145-152
While characterizing a therapeutic IgG4 monoclonal antibody (mAb), we observed a variant with a mass 1177 Da larger than the predominant mAb form that could not be ascribed to previously described modifications. Through successive rounds of experimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1e0a9ad5efc8023ecf3d172f21056e
https://doi.org/10.1080/19420862.2018.1540254
https://doi.org/10.1080/19420862.2018.1540254
Autor:
Thai H. Ho, Daniel W. Cramer, Shadi Ferdosi, Xifeng Wu, Tao Le, Lei Fu, Erik P. Castle, Harvey I. Pass, Karen S. Anderson, Paul Maranian, David E. C. Cole, Douglas S. Rehder, Chad R. Borges
Publikováno v:
Journal of Proteome Research. 17:543-558
Glycans represent a promising but only marginally accessed source of cancer markers. We previously reported the development of a molecularly bottom-up approach to plasma and serum (P/S) glycomics based on glycan linkage analysis that captures feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a01a0b7551a8626ff68003395fad9e2
https://doi.org/10.1021/acs.jproteome.7b00672
https://doi.org/10.1021/acs.jproteome.7b00672
Glycan structure of Gc Protein-derived Macrophage Activating Factor as revealed by mass spectrometry
Autor:
Douglas S. Rehder, Chad R. Borges
Publikováno v:
Archives of Biochemistry and Biophysics. 606:167-179
Disagreement exists regarding the O-glycan structure attached to human vitamin D binding protein (DBP). Previously reported evidence indicated that the O-glycan of the Gc1S allele product is the linear core 1 NeuNAc-Gal-GalNAc-Thr trisaccharide. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ff0cee1dc0ae26dd08a5b48bb9f251
https://doi.org/10.1016/j.abb.2016.08.006
https://doi.org/10.1016/j.abb.2016.08.006
Publikováno v:
Molecular & Cellular Proteomics. 14:1546-1555
Serum osteocalcin (Oc) concentration is a highly specific measure of bone turnover, but its circulating proteoform(s) have not been well defined. Based on immunological methods, the major forms are thought to be the intact polypeptide and a large N-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8519e849d2e4c2d75aca7b32358faebd
https://doi.org/10.1074/mcp.m114.047621
https://doi.org/10.1074/mcp.m114.047621
Autor:
Christian S. Breburda, Sally Jensen, Douglas S. Rehder, Hussein N. Yassine, Matthew R. Schaab, Boriana R. Nikolova, Chad R. Borges, Nisha D. Sherma
Publikováno v:
Molecular & Cellular Proteomics. 13:1890-1899
S-cysteinylated albumin and methionine-oxidized apolipoprotein A-I (apoA-I) have been posed as candidate markers of diseases associated with oxidative stress. Here, a dilute-and-shoot form of LC-electrospray ionization-MS requiring half a microliter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c32675998ba93278a025e94358e30d
https://doi.org/10.1074/mcp.m114.038455
https://doi.org/10.1074/mcp.m114.038455
Autor:
Sai Buddi, Douglas S. Rehder, Chad R. Borges, Randall W. Nelson, Matthew R. Schaab, Thomas J. Taylor, Paul E. Oran, Jason W. Jarvis, Stephen P Rogers
Publikováno v:
Clinical Chemistry. 57:719-728
BACKGROUNDIn 2008, the US Food and Drug Administration (FDA) issued a Guidance for Industry statement formally recognizing (during drug development) the conjoined nature of type 2 diabetes (T2D) and cardiovascular disease (CVD), which has precipitate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d242deee58f2c908e3dba492dee1187
https://doi.org/10.1373/clinchem.2010.156976
https://doi.org/10.1373/clinchem.2010.156976
Publikováno v:
Protein Science. 18:2036-2042
On the basis of the results of activity studies, previous reports have suggested that vitamin D binding protein (DBP) is significantly or even completely deglycosylated in cancer patients, eliminating the molecular precursor of the immunologically im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73d3534d5bef83d3d14f8b7e68f78453
https://doi.org/10.1002/pro.214
https://doi.org/10.1002/pro.214
Autor:
Rashida Williams, David E. C. Cole, Thomas O. Carpenter, Betty Y.L. Wong, Douglas S. Rehder, Chad R. Borges, Lei Fu
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 159
The gene (GC) for the vitamin D binding protein (DBP) shows significant genetic variation. Two missense variants, p.D432E and p.T436K, are common polymorphisms and both may influence vitamin D metabolism. However, less common variants, identified bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0561db2c074e9fbeb7775f90136ff9
https://pubmed.ncbi.nlm.nih.gov/26924582
https://pubmed.ncbi.nlm.nih.gov/26924582
Autor:
Paul E. Oran, Randall W. Nelson, Douglas S. Rehder, Jason W. Jarvis, Chad R. Borges, Olgica Trenchevska, Dobrin Nedelkov, Nisha D. Sherma
Publikováno v:
Proteome Science
Background The cytokine MIF (Macrophage Migration Inhibitory Factor) has diverse physiological roles and is present at elevated concentrations in numerous disease states. However, its molecular heterogeneity has not been previously investigated in bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec8d8418f13bda3a2769b9e704d8369
https://doi.org/10.1186/s12953-014-0052-3
https://doi.org/10.1186/s12953-014-0052-3