Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Douglas S Jones"'
Autor:
Bruce J MacFadden, Douglas S Jones, Nathan A Jud, Jorge W Moreno-Bernal, Gary S Morgan, Roger W Portell, Victor J Perez, Sean M Moran, Aaron R Wood
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170300 (2017)
The late Miocene was an important time to understand the geological, climatic, and biotic evolution of the ancient New World tropics and the context for the Great American Biotic Interchange (GABI). Despite this importance, upper Miocene deposits con
Externí odkaz:
https://doaj.org/article/c95495a0a4ad4a92bff4e46a16d9f1f6
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16112 (2011)
BackgroundThe Ecballium elaterium trypsin inhibitor (EETI-II), a 28-amino acid member of the knottin family of peptides, contains three interwoven disulfide bonds that form multiple solvent-exposed loops. Previously, the trypsin binding loop of EETI-
Externí odkaz:
https://doaj.org/article/4e230f00ace64e6c86bd000d5b1c272c
Lower Miocene stratigraphy along the Panama Canal and its bearing on the Central American Peninsula.
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2791 (2008)
Before the formation of the Central American Isthmus, there was a Central American Peninsula. Here we show that southern Central America existed as a peninsula as early as 19 Ma, based on new lithostratigraphic, biostratigraphic and strontium chemost
Externí odkaz:
https://doaj.org/article/03a4fd67e28948ec89275444781146ec
Autor:
Jorge D. Carrillo-Briceño, Rodolfo Sánchez, Torsten M. Scheyer, Juan D. Carrillo, Massimo Delfino, Georgios L. Georgalis, Leonardo Kerber, Damián Ruiz-Ramoni, José L. O. Birindelli, Edwin-Alberto Cadena, Aldo F. Rincón, Martin Chavez-Hoffmeister, Alfredo A. Carlini, Mónica R. Carvalho, Raúl Trejos-Tamayo, Felipe Vallejo, Carlos Jaramillo, Douglas S. Jones, Marcelo R. Sánchez-Villagra
Publikováno v:
Swiss Journal of Palaeontology, Vol 140, Iss 1, Pp 1-76 (2021)
Abstract The Pliocene–Pleistocene transition in the Neotropics is poorly understood despite the major climatic changes that occurred at the onset of the Quaternary. The San Gregorio Formation, the younger unit of the Urumaco Sequence, preserves a f
Externí odkaz:
https://doaj.org/article/a760fcb72a0f4cbcaa5c94b73c3b36c7
Publikováno v:
Paleobiology. 47:551-573
The field of sclerochronology has long been known to paleobiologists. Yet, despite the central role of growth rate, age, and body size in questions related to macroevolution and evolutionary ecology, these types of studies and the data they produce h
Autor:
Douglas S. Jones, Jonathan D. Nardozzi, Katharine L. Sackton, Gulzar Ahmad, Esben Christensen, Lars Ringgaard, De-Kuan Chang, Ditte E. Jaehger, Jacob V. Konakondla, Martin Wiinberg, Katherine L. Stokes, Alvin Pratama, Karsten Sauer, Thomas L. Andresen
Publikováno v:
Jones, D S, Nardozzi, J D, Sackton, K L, Ahmad, G, Christensen, E, Ringgaard, L, Chang, D-K, Jaehger, D E, Konakondla, J V, Wiinberg, M, Stokes, K L, Pratama, A, Sauer, K & Andresen, T L 2022, ' Cell surface-tethered IL-12 repolarizes the tumor immune microenvironment to enhance the efficacy of adoptive T cell therapy ', Science Advances, vol. 8, no. 17, eabi8075 . https://doi.org/10.1126/sciadv.abi8075
Immune-activating cytokines such as interleukin-12 (IL-12) hold strong potential for cancer immunotherapy but have been limited by high systemic toxicities. We describe here an approach to safely harness cytokine biology for adoptive cell therapy thr
Autor:
Catherine M. Bollard, Ali Danesh, Chanson J. Brumme, Thomas Lars Andresen, Douglas S. Jones, Bruce D. Walker, Zabrina L. Brumme, Eva M. Stevenson, Thomas R Dilling, Shabnum Patel, Winnie Dong, Christiaan H. van Dorp, Adam R. Ward, Elizabeth Zale, Alan S. Perelson, R. Brad Jones, Darrell J. Irvine, Talia M. Mota, Chase D. McCann
Publikováno v:
Rockefeller University Press
The Journal of Experimental Medicine
The Journal of Experimental Medicine
McCann et al. describe the development and characterization of a new mouse model for studying HIV-specific T cell responses and testing various immunotherapeutic strategies, which they validate by demonstrating enhanced therapeutic effects of autolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8091fd378bb858dbe16f5383cf8d74c
https://hdl.handle.net/1721.1/133106
https://hdl.handle.net/1721.1/133106
Autor:
Alvin Pratama, Douglas S. Jones, Kate L. Stokes, Thomas Lars Andresen, Hólmfridur Halldórsdóttir, Gulzar Ahmad, Jonathan Nardozzi, Katharine Sackton, Ditte Elisabeth Jæhger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Acquired resistance is a major limiting factor for durable T cell therapies in solid tumors. Antigen escape pathways such as insufficient antigen coverage or loss of target antigen remain major resistance mechanisms that need to be address
Autor:
Jorge D, Carrillo-Briceño, Rodolfo, Sánchez, Torsten M, Scheyer, Juan D, Carrillo, Massimo, Delfino, Georgios L, Georgalis, Leonardo, Kerber, Damián, Ruiz-Ramoni, José L O, Birindelli, Edwin-Alberto, Cadena, Aldo F, Rincón, Martin, Chavez-Hoffmeister, Alfredo A, Carlini, Mónica R, Carvalho, Raúl, Trejos-Tamayo, Felipe, Vallejo, Carlos, Jaramillo, Douglas S, Jones, Marcelo R, Sánchez-Villagra
Publikováno v:
Swiss Journal of Palaeontology
The Pliocene–Pleistocene transition in the Neotropics is poorly understood despite the major climatic changes that occurred at the onset of the Quaternary. The San Gregorio Formation, the younger unit of the Urumaco Sequence, preserves a fauna that
Publikováno v:
Biodiversity Information Science and Standards 3: e37897
Over the last decade, the Integrated Digitized Biocollections (iDigBio) organization and the Advancing the Digitization of Biodiversity Collections (ADBC) grant program, both funded by the US National Science Foundation (NSF), have made large strides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f416043c39cfdef038a3b13b1d6a8d6
https://zenodo.org/record/3340251
https://zenodo.org/record/3340251