Výsledky vyhledávání - "Douglas R. Coil"

Desmoplastic small round cell tumor (DSRCT) xenografts and tissue culture lines: Establishment and initial characterization

Autor: Douglas R. Coil, John Mendoza, Dana Vardeman, Beppino C. Giovanella, Constantine S.A. Markides, Tony Kozielski, Linh H. Luong

Publikováno v: Oncology Letters

Desmoplastic small round cell tumor (DSRCT) is an extremely rare and aggressive neoplasm, which mainly affects young males and generally presents as a widely disseminated tumor within the peritoneal cavity. Due to the rarity of the tumor, its younger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0cac116578d1c743d620a9cbc34bc4
http://europepmc.org/articles/PMC3678573

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A first-in-human phase I study of CZ48, a lactone ring protected oral camptothecin, in patients with advanced solid tumors

Autor: Montaser Shaheen, Douglas R. Coil, Constantine S.A. Markides, Steven D. Weitman, Lucy Y. Liu, Devalingam Mahalingam, Zhisong Cao, Beppino C. Giovanella, Claire F. Verschraegen, John Sarantopoulos

Publikováno v: Journal of Clinical Oncology. 31:2578-2578

2578 Background: CZ48, the 20-O-propionate ester of camptothecin (CPT), is a prodrug of CPT first described by Cao et al. in 1998. The side-chain is enzymatically cleaved in tissues. This gives rise to CPT, a potent inhibitor of topoisomerase I. Meth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3abd16d472b2bfdf7f3f5292f85503e5
https://doi.org/10.1200/jco.2013.31.15_suppl.2578

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Abstract 2769: DSRCT: Establishing xenograft and tissue culture cell lines and assessing chemosensitivity

Autor: Beppino C. Giovanella, John Mendoza, Douglas R. Coil, Constantine S.A. Markides, Linh H. Luong, Anthony J. Kozielski, Dana Vardeman

Publikováno v: Cancer Research. 73:2769-2769

Desmoplastic small round cell tumor (DSRCT) is an extremely rare and aggressive neoplasm which mainly affects young males and generally presents as a widely disseminated tumor within the peritoneal cavity. Due to the rarity of the tumor, a younger an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cdf5acdf332dbe7cb5a6164084723f3b
https://doi.org/10.1158/1538-7445.am2013-2769

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