Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Douglas Osei-Hyiaman"'
Autor:
Derick N M Osakunor, Takafira Mduluza, Douglas Osei-Hyiaman, Karl Burgess, Mark E J Woolhouse, Francisca Mutapi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 12, p e0008866 (2020)
Helminths are parasitic worms that infect over a billion people worldwide. The pathological consequences from infection are due in part, to parasite-induced changes in host metabolic pathways. Here, we analyse the changes in host metabolic profiles,
Externí odkaz:
https://doaj.org/article/e72f60c89df84b64a419231f7f283b65
Autor:
James P. Hardwick, Douglas Osei-Hyiaman, Homer Wiland, Mohamed A. Abdelmegeed, Byoung-Joon Song
Publikováno v:
PPAR Research, Vol 2009 (2009)
Fatty liver disease is a common lipid metabolism disorder influenced by the combination of individual genetic makeup, drug exposure, and life-style choices that are frequently associated with metabolic syndrome, which encompasses obesity, dyslipidemi
Externí odkaz:
https://doaj.org/article/6e08d54dc7884ddfb9460f0f91a8bb96
Autor:
Noriyuki Kawamura, Tamaki Fujimori, Makoto Suzuki, Kumi Yamaki, Yoshiaki Ohashi, Hajime Sato, Kazunori Sasaki, Hiroyuki Yamamoto, Kosaku Shinoda, Douglas Osei-Hyiaman
Publikováno v:
Psychiatry and Clinical Neurosciences. 72:349-361
Aim This study sought to characterize the plasma metabolite profiling of patients with major depressive disorder (MDD). Methods Psychiatric assessments were made with the Structured Clinical Interview for DSM-IV Axis I Disorders. In the exploratory c
Autor:
Nathan J. Coffey, Grzegorz Godlewski, Jie Liu, Lee Chedester, Douglas Osei-Hyiaman, Resat Cinar, Ziyi Liu, Hiroshi Iwakura, Joshua K. Park, Malliga R. Iyer, Roy G. Smith, Bani Mukhopadhyay, George Kunos, Tony Jourdan
Publikováno v:
Cell Metab
Endocannabinoids acting on the cannabinoid-1 receptor (CB(1)R) or ghrelin acting on its receptor (GHS-R(1A)) both promote alcohol-seeking behavior, but an interaction between the two signaling systems has not been explored. Here we report that the pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad215baa4fe73f6fbb92e6909ef916e2
https://europepmc.org/articles/PMC6551287/
https://europepmc.org/articles/PMC6551287/
Autor:
George Kunos, Aya Hoshi, Hajime Tomatsu, Kaori Honda-Hanawa, Grzegorz Godlewski, Noriyuki Kawamura, Douglas Osei-Hyiaman, Yoshiaki Ohashi, Resat Cinar
Publikováno v:
Journal of the Endocrine Society
Plasma phosphoethanolamine (PEA) levels are significantly decreased in major depressive disorder (MDD) patients compared to healthy controls: Also, in chronic ACTH treatment mouse model of MDD, plasma and frontal cortex PEA were significantly decreas
Autor:
Grzegorz Godlewski, George Kunos, Aya Hoshi, Hajime Tomatsu, Resat Cinar, Kaori Honda-Hanawa, Douglas Osei-Hyiaman, Yoshiaki Ohashi, Noriyuki Kawamura
Publikováno v:
Journal of the Endocrine Society
Major depression is a chronic illness and a major component of disease burden, with high prevalence in women than in men. Plasma phosphoethanolamine (PEA) levels are significantly decreased in major depressive disorder (MDD) patients compared to heal
Autor:
Nathan J. Coffey, Hiroshi Iwakura, Jie Liu, Bani Mukhopadhyay, Lee Chedester, Resat Cinar, Joshua Park, Roy G. Smith, Douglas Osei-Hyiaman, Ziyi Liu, George Kunos, Tony Jourdan, Malliga R. Iyer, Grzegorz Godlewski
Publikováno v:
SSRN Electronic Journal.
The dynamic interplay between energy homeostasis and motivational behavior is exemplified by mediators involved in regulating both. Endocannabinoids acting via CB1 receptors (CB1R) or the stomach-derived hormone ghrelin acting via ghrelin receptors (
Autor:
Karsten Kristiansen, Yu Hong Lin, Lise Madsen, Douglas Osei-Hyiaman, Joseph R. Hibbeln, Robert J. Pawlosky, Anita Røyneberg Alvheim, Livar Frøyland, Marian K. Malde
Publikováno v:
Obesity (Silver Spring, Md.)
Suppressing hyperactive endocannabinoid tone is a critical target for reducing obesity. The backbone of both endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA) is the ω-6 fatty acid arachidonic acid (AA). Here we posited that excess
Autor:
Noriyuki, Kawamura, Kosaku, Shinoda, Hajime, Sato, Kazunori, Sasaki, Makoto, Suzuki, Kumi, Yamaki, Tamaki, Fujimori, Hiroyuki, Yamamoto, Douglas, Osei-Hyiaman, Yoshiaki, Ohashi
Publikováno v:
Psychiatry and clinical neurosciences. 72(5)
This study sought to characterize the plasma metabolite profiling of patients with major depressive disorder (MDD).Psychiatric assessments were made with the Structured Clinical Interview for DSM-IV Axis I Disorders. In the exploratory cohort, plasma
Autor:
Pal Pacher, Grzegorz Godlewski, George Kunos, Bani Mukhopadhyay, Fong Ming Mo, Joseph Tam, Resat Cinar, Judith Harvey-White, Jie Liu, Tony Jourdan, Douglas Osei-Hyiaman, Gergő Szanda
Publikováno v:
Scientific Reports
We report an unexpected link between aging, thermogenesis and weight gain via the orphan G protein-coupled receptor GPR3. Mice lacking GPR3 and maintained on normal chow had similar body weights during their first 5 months of life, but gained conside