Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Douglas O, Ochora"'
Autor:
Joseph G. Amwoma, Sarah Kituyi, Dancan M. Wakoli, Douglas O. Ochora, Gladys Chemwor, Risper Maisiba, Winnie Okore, Benjamin Opot, Dennis Juma, Eric M.O. Muok, Eric C. Garges, Timothy E. Egbo, Franklin N. Nyabuga, Ben Andagalu, Hoseah M. Akala
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101596- (2024)
The molecular mechanism underlying Plasmodium falciparum's persistence in the asymptomatic phase of infection remains largely unknown. However, large-scale shifts in the parasites' gene expression during asymptomatic infections may enhance phenotypic
Externí odkaz:
https://doaj.org/article/14e8872319944adba05ac4c2850458d6
Autor:
Winnie Okore, Collins Ouma, Raphael O Okoth, Redemptah Yeda, Luicer O Ingasia, Edwin W Mwakio, Douglas O Ochora, Duncan M Wakoli, Joseph G Amwoma, Gladys C Chemwor, Jackline A Juma, Charles O Okudo, Agnes C Cheruiyot, Benjamin H Opot, Dennis Juma, Timothy E Egbo, Ben Andagalu, Amanda Roth, Edwin Kamau, Hoseah M Akala
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0298585 (2024)
Single nucleotide polymorphisms (SNPs) in the Plasmodium falciparum multi-drug resistance protein 1 (Pfmrp1) gene have previously been reported to confer resistance to Artemisinin-based Combination Therapies (ACTs) in Southeast Asia. A total of 300 s
Externí odkaz:
https://doaj.org/article/3552aaa210124c479cb095b7b88701bf
Autor:
Dancan M. Wakoli, Bartholomew N. Ondigo, Douglas O. Ochora, Joseph G. Amwoma, Winnie Okore, Edwin W. Mwakio, Gladys Chemwor, Jackeline Juma, Raphael Okoth, Charles Okudo, Redemptah Yeda, Benjamin H. Opot, Agnes C. Cheruiyot, Dennis Juma, Amanda Roth, Benhards R. Ogutu, Daniel Boudreaux, Ben Andagalu, Hoseah M. Akala
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Dihydroartemisinin-piperaquine (DHA-PPQ) is an alternative first-line antimalarial to artemether-lumefantrine in Kenya. However, recent reports on the emergence of PPQ resistance in Southeast Asia threaten its continued use in Ken
Externí odkaz:
https://doaj.org/article/f4342a5daf924e1da218017f3888927d
Autor:
Redemptah Yeda, Charles Okudo, Eunice Owiti, Gladys Biwot, Cliff Momanyi, Winnie Korir, Thoya Mitsanze, Caroline Tegerei, Dennis Juma, Benjamin Opot, Edwin Mwakio, Gladys Chemwor, Raphael Okoth, Douglas O. Ochora, Agnes C. Cheruiyot, Amanda Roth, Hoseah M. Akala, Ben Andagalu
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-7 (2022)
Abstract Background The ABO blood groups consist of A, B, and H carbohydrate antigens, which regulate protein activities during malaria infection in humans. Understanding the interplay between the malaria parasite and blood group antigens is essentia
Externí odkaz:
https://doaj.org/article/cbeecda63722492491d1164c22b7f3d8
Autor:
Douglas O. Ochora, Reagan M. Mogire, Rael J. Masai, Redemptah A. Yeda, Edwin W. Mwakio, Joseph G. Amwoma, Dancan M. Wakoli, Abiy Yenesew, Hoseah M. Akala
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18863- (2023)
High malaria mortality coupled with increased emergence of resistant multi-drug resistant strains of Plasmodium parasite, warrants the development of new and effective antimalarial drugs. However, drug design and discovery are costly and time-consumi
Externí odkaz:
https://doaj.org/article/a258085fcfe7472da69c1f3c36cc1485
Autor:
Douglas O. Ochora, Esezah K. Kakudidi, Jane Namukobe, Perpetua Ipulet, Dancan M. Wakoli, Winnie Okore, Edwin W. Mwakio, Redempthah A. Yeda, Agnes C. Cheruiyot, Dennis W. Juma, Ben Andagalu, Amanda L. Roth, Bernhards R. Ogutu, Abiy Yenesew, Hoseah M. Akala
Publikováno v:
Plants, Vol 11, Iss 1, p 47 (2021)
Malaria is the most lethal parasitic disease in the world. The frequent emergence of resistance by malaria parasites to any drug is the hallmark of sustained malaria burden. Since the deployment of artemisinin-based combination therapies (ACTs) it is
Externí odkaz:
https://doaj.org/article/27b43c3627354952ad059357c663a37f
Autor:
Douglas O, Ochora, Esezah, Kakudidi, Jane, Namukobe, Matthias, Heydenreich, Paolo, Coghi, Li Jun, Yang, Edwin W, Mwakio, Ben, Andagalu, Amanda, Roth, Hoseah M, Akala, Vincent K W, Wong, Abiy, Yenesew
Publikováno v:
Natural product research. 36(11)
Extracts from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26a49aac0523e93f36961b04e318607e
https://pubmed.ncbi.nlm.nih.gov/34000936
https://pubmed.ncbi.nlm.nih.gov/34000936
Autor:
Douglas O. Ochora, Paolo Coghi, Vincent Kam Wai Wong, Edwin W. Mwakio, Matthias Heydenreich, Amanda L. Roth, Esezah Kakudidi, Li Jun Yang, Abiy Yenesew, Ben Andagalu, Jane Namukobe, Hoseah M. Akala
Extracts from Securidaca longipedunculata showed antiplasmodial activities against reference clones and clinical isolates using SYBR Green I method. A new benzophenone, 2,3,4,5-tetramethoxybenzophenone (1) was isolated and characterized along with se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a4d892065f6a5fc473294f96ac15ae2
