Výsledky vyhledávání - "Douglas M. Warner"

Pathways over Time: Functional Genomics Research in an Introductory Laboratory Course

Autor: Clare M. O'Connor, Douglas M. Warner, Larry H. Ludlow, Todd D. Reeves

Publikováno v: CBE Life Sciences Education

Introductory students in a large, multisection course-based undergraduate research experience acquired content knowledge and research skills while studying the evolutionary conservation of enzymes involved in methionine synthesis. The course research

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3056efd85a2e33564946b9635881c7a
https://pubmed.ncbi.nlm.nih.gov/29326101

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Research for All: Large Introductory Laboratory Classes Investigate the Evolutionary Conservation of Metabolic Pathways

Autor: Douglas M. Warner, Clare M. O'Connor

Publikováno v: The FASEB Journal. 30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae47d982a726ddcb0556aa3da598d6b1
https://doi.org/10.1096/fasebj.30.1_supplement.662.1

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SoxS Increases the Expression of the Zinc Uptake System ZnuACB in an Escherichia coli Murine Pyelonephritis Model

Autor: Stuart B. Levy, Douglas M. Warner

Publikováno v: Journal of Bacteriology. 194:1177-1185

Paralogous transcriptional regulators MarA, Rob, and SoxS act individually and together to control expression of more than 80 Escherichia coli genes. Deletion of marA, rob, and soxS from an E. coli clinical isolate prevents persistence beyond 2 days

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768bf864b6d59ab36d913edf1e580491
https://doi.org/10.1128/jb.05451-11

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Different effects of transcriptional regulators MarA, SoxS and Rob on susceptibility of Escherichia coli to cationic antimicrobial peptides (CAMPs): Rob-dependent CAMP induction of the marRAB operon

Autor: Stuart B. Levy, Douglas M. Warner

Publikováno v: Microbiology. 156:570-578

Cationic antimicrobial peptides (CAMPs), a component of the mammalian immune system, protect the host from bacterial infections. The roles of the Escherichia coli transcriptional regulators MarA, SoxS and Rob in susceptibility to these peptides were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1cc10a95ae8d31412b38415fbf295f3
https://doi.org/10.1099/mic.0.033415-0

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Pathways over Time: a Semester‐long Research Investigation for the Introductory Laboratory

Autor: Douglas M. Warner, Clare M. O'Connor

Publikováno v: The FASEB Journal. 29

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::62a47f4774524ca25b82a335c3ce1c62
https://doi.org/10.1096/fasebj.29.1_supplement.559.32

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Involvement of MarR and YedS in carbapenem resistance in a clinical isolate of Escherichia coli from China

Autor: Qiwen Yang, Douglas M. Warner, Yingchun Xu, Stuart B. Levy, Valérie Duval, Minjun Chen

Publikováno v: Antimicrobial agents and chemotherapy. 57(4)

A carbapenem-resistant clinical isolate of Escherichia coli , which lacked OmpF and OmpC porins, carried a marR mutation and expressed a functional yedS , a normally nontranslated gene. MarR and YedS are described here as having effects on the abilit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6170dd0b069b6c840dc8e816cae6aa3b
https://pubmed.ncbi.nlm.nih.gov/23318808

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Clinically Relevant Mutations that Cause Derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux Pump System Confer Different Levels of Antimicrobial Resistance and In Vivo Fitness

Autor: Ann E. Jerse, William M. Shafer, Douglas M. Warner

The MtrC-MtrD-MtrE efflux pump system confers resistance to macrolide antibiotics and antimicrobial substances of the host innate defence. Clinical isolates with increased resistance to erythromycin and azithromycin frequently harbour mutations in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e9ab4ec3062bb73d5611d9d9584091
https://europepmc.org/articles/PMC2602950/

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Phenotypic and Genotypic Analyses of Neisseria gonorrhoeae Isolates That Express Frequently Recovered PorB PIA Variable Region Types Suggest that Certain P1a Porin Sequences Confer a Selective Advantage for Urogenital Tract Infection▿

Autor: Douglas M. Warner, Sanjay Ram, Christine E. Keys, William M. Shafer, Margaret C. Bash, Lotisha E. Garvin, Ann E. Jerse

Typing of the porB variable region (VR) is an epidemiological tool that classifies gonococcal strains based on sequence differences in regions of the porB gene that encode surface-exposed loops. The frequent isolation of certain porB VR types suggest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ef6533f944f9443b7b1a3dfb860c1f
https://europepmc.org/articles/PMC2493220/

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Regulation of the MtrC-MtrD-MtrE efflux-pump system modulates the in vivo fitness of Neisseria gonorrhoeae

Autor: Douglas M. Warner, William M. Shafer, Ann E. Jerse, Jason P. Folster

Publikováno v: The Journal of infectious diseases. 196(12)

The Neisseria gonorrhoeae MtrC-MtrD-MtrE multidrug-resistance efflux pump expels macrolide antibiotics, penicillin, and antimicrobial effectors of the innate defense. Mutation of the mtrR locus, which encodes a transcriptional repressor of the mtrCDE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1fcef29a58f5e07f72c5f47ac6607fa
https://pubmed.ncbi.nlm.nih.gov/18190261

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