Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Douglas Laird, A."'
Autor:
Nicholas C. Turner, A. Douglas Laird, Melinda L. Telli, Hope S. Rugo, Audrey Mailliez, Johannes Ettl, Eva-Maria Grischke, Lida A. Mina, Judith Balmaña, Peter A. Fasching, Sara A. Hurvitz, Julia F. Hopkins, Lee A. Albacker, Jijumon Chelliserry, Ying Chen, Umberto Conte, Andrew M. Wardley, Mark E. Robson
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract These analyses explore the impact of homologous recombination repair gene mutations, including BRCA1/2 mutations and homologous recombination deficiency (HRD), on the efficacy of the poly(ADP-ribose) polymerase (PARP) inhibitor talazoparib i
Externí odkaz:
https://doaj.org/article/38e11546389a453baf13464d8594cd8f
Autor:
Mylène Ratelle, Andrew Spring, Brian Douglas Laird, Leon Andrew, Deborah Simmons, Alexa Scully, Kelly Skinner
Publikováno v:
FACETS, Vol 7, Iss , Pp 343-359 (2022)
Resource development and climate change are increasing concerns regarding safe water for Indigenous people in Canada. A research study was completed to characterize the consumption of water and beverages prepared with water and identify the perceptio
Externí odkaz:
https://doaj.org/article/0cbb26c80abc46a7afa65347c75e2751
Autor:
Daniel J. DeAngelo, Wendy Stock, Anthony S. Stein, Andrei Shustov, Michaela Liedtke, Charles A. Schiffer, Erik Vandendries, Katherine Liau, Revathi Ananthakrishnan, Joseph Boni, A. Douglas Laird, Luke Fostvedt, Hagop M. Kantarjian, Anjali S. Advani
Publikováno v:
Blood Advances, Vol 1, Iss 15, Pp 1167-1180 (2017)
Abstract: This study evaluated the safety, antitumor activity, pharmacokinetics, and pharmacodynamics of inotuzumab ozogamicin (InO) for CD22-positive relapsed/refractory acute lymphoblastic leukemia. In phase 1, patients received InO 1.2 (n = 3), 1.
Externí odkaz:
https://doaj.org/article/75e7d5b654074258b13162642cc5791e
Autor:
A. Douglas Laird, Peter Lamb, David J. Matthews, Olivia Yturralde, Stephanie Dale, Sanh T. Lam, Frauke Bentzien, Kelly Engell, Felix Chu, F. Michael Yakes, Artur Plonowski, Jenny Young, Jason Chen, Wendy Abulafia, Paul Keast, Charles K. Marlowe, Wentao Zhang, Christopher T. Jaeger, Peiwen Yu, Kwang-Ai Won, Jianming Wu, Xiangnan Du, Fawn Qian, Pin P. Hsu, Kyoko Yamaguchi, Paul Foster
Dose-response relationships for inhibition of PI3K pathway signaling by XL147 in tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260634cb87fb5d622eb4168f46e64fc0
https://doi.org/10.1158/1535-7163.22501281.v1
https://doi.org/10.1158/1535-7163.22501281.v1
Autor:
A. Douglas Laird, Peter Lamb, David J. Matthews, Olivia Yturralde, Stephanie Dale, Sanh T. Lam, Frauke Bentzien, Kelly Engell, Felix Chu, F. Michael Yakes, Artur Plonowski, Jenny Young, Jason Chen, Wendy Abulafia, Paul Keast, Charles K. Marlowe, Wentao Zhang, Christopher T. Jaeger, Peiwen Yu, Kwang-Ai Won, Jianming Wu, Xiangnan Du, Fawn Qian, Pin P. Hsu, Kyoko Yamaguchi, Paul Foster
Effects of XL147 on PI3K Signaling Pathway in OVCAR-3 and U87-MG cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f71be1beb32a7e6d834de7d7f0c096d
https://doi.org/10.1158/1535-7163.22501287.v1
https://doi.org/10.1158/1535-7163.22501287.v1
Autor:
Alison H. Joly, Yu-Chien Chou, Justin Lesch, Lillian Lee, Stefan Engst, A. Douglas Laird, Andrew You, Jessica Orf, Belinda Cancilla, Frauke Bentzien, Felix Chu, Fawn Qian, Peiwen Yu, Yongchang Shi, Kyoko Yamaguchi, Jenny Tan, Jason Chen, F. Michael Yakes
PDF file - 104KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cd3621fbfa51d438f48142646da225
https://doi.org/10.1158/1535-7163.22496638.v1
https://doi.org/10.1158/1535-7163.22496638.v1
Autor:
A. Douglas Laird, Peter Lamb, David J. Matthews, Olivia Yturralde, Stephanie Dale, Sanh T. Lam, Frauke Bentzien, Kelly Engell, Felix Chu, F. Michael Yakes, Artur Plonowski, Jenny Young, Jason Chen, Wendy Abulafia, Paul Keast, Charles K. Marlowe, Wentao Zhang, Christopher T. Jaeger, Peiwen Yu, Kwang-Ai Won, Jianming Wu, Xiangnan Du, Fawn Qian, Pin P. Hsu, Kyoko Yamaguchi, Paul Foster
Dysregulation of PI3K/PTEN pathway components, resulting in hyperactivated PI3K signaling, is frequently observed in various cancers and correlates with tumor growth and survival. Resistance to a variety of anticancer therapies, including receptor ty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad3a94f3645fe9f5dc53f0c5c6b6714f
https://doi.org/10.1158/1535-7163.c.6536730.v1
https://doi.org/10.1158/1535-7163.c.6536730.v1
Autor:
A. Douglas Laird, Peter Lamb, David J. Matthews, Olivia Yturralde, Stephanie Dale, Sanh T. Lam, Frauke Bentzien, Kelly Engell, Felix Chu, F. Michael Yakes, Artur Plonowski, Jenny Young, Jason Chen, Wendy Abulafia, Paul Keast, Charles K. Marlowe, Wentao Zhang, Christopher T. Jaeger, Peiwen Yu, Kwang-Ai Won, Jianming Wu, Xiangnan Du, Fawn Qian, Pin P. Hsu, Kyoko Yamaguchi, Paul Foster
Effects of XL147 on PI3K Signaling Pathway in EGF-Stimulated PC-3 Cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9669a150af5e5be12d3299122d031454
https://doi.org/10.1158/1535-7163.22501293.v1
https://doi.org/10.1158/1535-7163.22501293.v1
Autor:
A. Douglas Laird, Peter Lamb, David J. Matthews, Olivia Yturralde, Stephanie Dale, Sanh T. Lam, Frauke Bentzien, Kelly Engell, Felix Chu, F. Michael Yakes, Artur Plonowski, Jenny Young, Jason Chen, Wendy Abulafia, Paul Keast, Charles K. Marlowe, Wentao Zhang, Christopher T. Jaeger, Peiwen Yu, Kwang-Ai Won, Jianming Wu, Xiangnan Du, Fawn Qian, Pin P. Hsu, Kyoko Yamaguchi, Paul Foster
Effects of XL147 on PI3K Pathway Signaling in A549, MDA-MB-468 and LS174T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a3f60276d69e7049037ddfa915cc5a
https://doi.org/10.1158/1535-7163.22501284
https://doi.org/10.1158/1535-7163.22501284
Autor:
A. Douglas Laird, Peter Lamb, David J. Matthews, Olivia Yturralde, Stephanie Dale, Sanh T. Lam, Frauke Bentzien, Kelly Engell, Felix Chu, F. Michael Yakes, Artur Plonowski, Jenny Young, Jason Chen, Wendy Abulafia, Paul Keast, Charles K. Marlowe, Wentao Zhang, Christopher T. Jaeger, Peiwen Yu, Kwang-Ai Won, Jianming Wu, Xiangnan Du, Fawn Qian, Pin P. Hsu, Kyoko Yamaguchi, Paul Foster
Assessment of effects of XL147 on Nutrient-Dependent mTOR Signaling Pathway in Ramos cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777dcba04ed9652416df56917277426b
https://doi.org/10.1158/1535-7163.22501290.v1
https://doi.org/10.1158/1535-7163.22501290.v1