Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Douglas L. Vizard"'
Increased Sensitivity in Antigen Detection with Fluorescent Latex Nanosphere−IgG Antibody Conjugates
Autor:
Douglas L. Vizard, William E. McLaughlin, M Catherine Muenker, John William Harder, Tao Ji, Rao Papineni
Publikováno v:
Bioconjugate Chemistry. 21:427-435
IgG antibodies were conjugated to Kodak X-Sight nanospheres to develop fluorescent-labeled antibodies using two different synthetic routes: one involving the DTT reduction method, and the other involving Traut's Reagent modification method. These two
Publikováno v:
The FASEB Journal. 26
Autor:
William E. McLaughlin, Sean Orton, Rao V. Papineni, Douglas L. Vizard, Tao Ji, Jingyi Pan, Hans F. Schmitthenner
Publikováno v:
The FASEB Journal. 24
Autor:
Gilbert Feke, Douglas L. Vizard, William E. McLaughlin, Sean Orton, Rao Papineni, Douglas O. Wood
Publikováno v:
Computer methods and programs in biomedicine. 99(1)
A radiographic system is optimized for the contrast inherent to small animals and is developed for a multi-modal imaging system devised for in-vivo studies. The range of X-ray energies utilized (generally considered ''soft X-rays'') enables enhanced
Autor:
J. Paul Robinson, Douglas L. Vizard, Yanan Jiang, Valery Patsekin, Heidi Hall, Silas J. Leavesley
Publikováno v:
SPIE Proceedings.
Molecular imaging is a rapidly growing area of research, fueled by needs in pharmaceutical drug-development for methods for high-throughput screening, pre-clinical and clinical screening for visualizing tumor growth and drug targeting, and a growing
Autor:
Megan Schmidt, Wenyi Che, W. Matthew Leevy, Victoria Jacobs, Sean Orton, Gilbert Feke, M Catherine Muenker, Tao Ji, Seth T. Gammon, William E. McLaughlin, Douglas L. Vizard
Publikováno v:
Nature Methods. 6:v-vi
Near-infrared fluorescent Kodak X-Sight 761 Nanospheres were readily absorbed by melanoma cancer cells growing in culture. When we implanted these cells in mice, they grew into palpable tumors that maintained the nanoparticle cell label. This facile
Autor:
Rao Papineni, Gilbert Feke, Douglas O. Wood, William E. McLaughlin, W. Matthew Leevy, Douglas L. Vizard, Benjamin F Geldhof, M Catherine Muenker, Sean Orton, Manisha Patel
Publikováno v:
Nature Methods. 5:iii-iv
We have combined the KODAK In-Vivo Multispectral Imaging System FX with a new animal rotation module. This module enables the precise co-registration of X-ray images with spectrally unmixed fluorescence images of mice rotated through various cranioca
Publikováno v:
Nature Methods. 5:i-ii
The new KODAK In-Vivo Multispectral Imaging System FX uses an innovative calibration tool, the Kodak Epi Field Flattening Screen, which provides efficient calibration over a wide range of excitation and emission filter combinations. When used with Ko
Abstract 5329: Degradable multimodal nanoparticles with fluorescence and magnetic resonance contrast
Publikováno v:
Cancer Research. 71:5329-5329
Molecular Imaging is making rapid strides as a tool in understanding and the cure of cancer. Like no panacea, here again a need of multimodality exists, where more than one modality is becoming a necessity to cogently decipher the role or action of t
Autor:
Sean Orton, Douglas L. Vizard, William E. McLaughlin, Jingyi Pan, Hans Schmitthenner, Tao Ji, Rao Papineni
Publikováno v:
Cancer Research. 70:2649-2649
A non-invasive means of targeting bisphophonate to specific skeletal sites, along with the passive binding/decay kinetics of the near-infrared bisphosphanate analog to the skeleton are determined. Bone is the third common site where breast, lung, and