Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Douglas L. Tolson"'
Publikováno v:
FEMS Microbiology Letters. 154:17-22
The humoral immune response mounted in BALB/c mice against bovine serum albumin or cholera toxin B subunit was compared when the antigens were associated with liposomes composed of either archaeal ether lipids or conventional lipids. Antibody titres
Publikováno v:
Canadian Journal of Microbiology. 44:896-904
Proteus mirabilis is a common cause of upper urinary tract infections. Fimbriae-mediated adherence of this organism to urinary tract epithelium and invasion of host cells are factors thought to be important in its pathogenesis. We have assessed the e
Publikováno v:
Canadian Journal of Microbiology. 43:709-717
Proteus mirabilis is a common causative agent of human urinary tract infections, especially in catheterized patients and in those patients with structural abnormalities of the urinary tract. In addition to the production of hemolysin and urease, fimb
Publikováno v:
Journal of Liposome Research. 6:755-776
Liposomes in the 200 nm size range were prepared from the ether lipids extracted from various Archaeobacteria (coined archaeosomes), and from conventional lipids. The entrapment of peroxidase or carboxyfluorescein was used to compare the in vitro upt
Publikováno v:
Infection and Immunity. 58:3500-3507
Murine peritoneal macrophages were infected with living, virulent Leishmania donovani promastigotes. At intervals after infection, the macrophage surfaces were probed for the expression of lipophosphoglycan (LPG) epitopes by immunofluorescence with a
Autor:
Douglas L. Tolson, Emanuela Handman, Antony Bacic, Terry W. Pearson, Malcolm J. McConville, Martin J Elhay, Michelle Kelleher
Publikováno v:
Molecular and Biochemical Parasitology. 40:255-267
Lipophosphoglycan (LPG) of Leishmania is a polymorphic molecule comprising an alkylglycerol anchor, a conserved oligosaccharide core and a species-specific polymer of oligosaccharide repeats joined by phosphodiester bonds. This molecule, together wit
Publikováno v:
Glycobiology. 1:63-69
Monoclonal antibodies directed against the lipophosphoglycan of Leishmania donovani were used to characterize two glycosylation variants of the parasite. One of the variants was found to be totally deficient in the synthesis and expression of lipopho
Autor:
Corinna Tuckey, Armando Jardim, Hung-Sia Teh, Douglas L. Tolson, Caroline E. Stebeck, Robert W. Olafson, Terry W. Pearson, L. F. Schnur, Robert P. Beecroft
Publikováno v:
Infection and immunity. 62(11)
Kinetoplastid membrane protein 11 (KMP-11) from Leishmania donovani is an abundant 11-kDa surface membrane glycoprotein. Lymph node cells from mice of six different H-2 haplotypes immunized with KMP-11 or with L. donovani promastigotes were stimulate
Publikováno v:
Parasitology research. 80(6)
Monoclonal antibody (mAb) CA7AE binds specifically to the phosphorylated Gal-beta 1,4-Man disaccharide repeat epitope of Leishmania donovani lipophosphoglycan (LPG). This mAb detected the repeat epitope in most but not all of a wide variety of Leishm
Autor:
Douglas L. Tolson, Terry W. Pearson, Robert P. Beecroft, Margaret K. Liu, Jennifer P. Richardson
Publikováno v:
Molecular and Biochemical Parasitology. 31:203-216
An immunodominant species-specific surface glycoprotein antigen was purified from procyclic culture forms of Trypanosoma brucei rhodesiense using lectin affinity chromatography and a monoclonal antibody immunoadsorbent. The purified molecule appears