Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Douglas Kling"'
Autor:
Stephen J. Nicholls, Marc Ditmarsch, John J. Kastelein, Scott P. Rigby, Douglas Kling, Danielle L. Curcio, Nicholas John Alp, Michael H. Davidson
Publikováno v:
Nature medicine, 28(8), 1672-1678. Nature Publishing Group
Global guidelines for the management of high-cardiovascular-risk patients include aggressive goals for low-density lipoprotein cholesterol (LDL-C). Statin therapy alone is often insufficient to reach goals and nonstatin options have limitations. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5885fc425a51c1d1e0eb56e44c83b5f0
http://www.scopus.com/inward/record.url?scp=85135835966&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85135835966&partnerID=8YFLogxK
Autor:
G. Kees Hovingh, Larry Lo, Mads D M Engelmann, Paul M. Ridker, Pablo Pergola, Florian M.M. Baeres, Peter Libby, Rescue Investigators, Milana Ivkovic, Michael H. Davidson, Matt Devalaraja, Dominic S. Raj, Douglas Kling
Publikováno v:
The Lancet, 397(10289), 2060-2069. Elsevier Limited
Background: IL-6 has emerged as a pivotal factor in atherothrombosis. Yet, the safety and efficacy of IL-6 inhibition among individuals at high atherosclerotic risk but without a systemic inflammatory disorder is unknown. We therefore addressed wheth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe112adc911a8223e480073fc522b000
https://doi.org/10.1016/s0140-6736(21)00520-1
https://doi.org/10.1016/s0140-6736(21)00520-1
Autor:
Joga Gobburu, Kristen L. Nowak, Rahul Kakkar, Douglas Kling, Michel Chonchol, Larry Lo, Wansu Park, Matt Devalaraja, Michael H. Davidson
Publikováno v:
Kidney360
BACKGROUND: Chronic systemic inflammation is highly prevalent in patients with CKD (measured as an elevated high-sensitivity C-reactive protein, hsCRP) and independently associated with cardiovascular events and all-cause mortality. An IL-6 blocker t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f949961e541d4285a18459785ba244d
https://doi.org/10.34067/kid.0005862020
https://doi.org/10.34067/kid.0005862020
Autor:
Marc Ditmarsch, Douglas Kling, Danielle Curcio, Nicholas Alp, John Kastelein, Michael Davidson
Publikováno v:
Journal of Clinical Lipidology. 16:e67-e68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df5c1825aa2fa378a8995477af347e81
https://doi.org/10.1016/j.jacl.2022.05.051
https://doi.org/10.1016/j.jacl.2022.05.051
Autor:
Stephen J, Nicholls, Marc, Ditmarsch, John J, Kastelein, Scott P, Rigby, Douglas, Kling, Danielle L, Curcio, Nicholas John, Alp, Michael H, Davidson
Publikováno v:
Nature medicine. 28(8)
Global guidelines for the management of high-cardiovascular-risk patients include aggressive goals for low-density lipoprotein cholesterol (LDL-C). Statin therapy alone is often insufficient to reach goals and nonstatin options have limitations. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44ebcea87ced99aae046b78f2c2bf9ba
https://pubmed.ncbi.nlm.nih.gov/35953719
https://pubmed.ncbi.nlm.nih.gov/35953719
Autor:
Douglas Kling
Publikováno v:
Journal of Clinical Lipidology. 16:e73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7432057ff739d7bb766ea40cf025b80
https://doi.org/10.1016/j.jacl.2022.05.059
https://doi.org/10.1016/j.jacl.2022.05.059
Autor:
Andrey V. Susekov, Michael H. Davidson, Ben N. Machielse, Kevin C. Maki, Børge G. Nordestgaard, Douglas Kling, Marat V. Ezhov, John J.P. Kastelein
Publikováno v:
Journal of clinical lipidology, 8(1), 94-106. Elsevier BV
Omega-3 fatty acids in free fatty acid form have enhanced bioavailability, and plasma levels are less influenced by food than for ethyl ester forms. The aim was to evaluate the safety and lipid-altering efficacy in subjects with severe hypertriglycer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6e4cc9343cffbafb36f648f3a5ec48
https://doi.org/10.1016/j.jacl.2013.10.003
https://doi.org/10.1016/j.jacl.2013.10.003
Publikováno v:
Journal of Clinical Lipidology. 6:573-584
Omega-3 (OM-3) fatty acid products are indicated for the treatment of severe hypertriglyceridemia; however, the omega-3-acid ethyl ester (OM-3 EE) formulations require significant pancreatic lipase stimulation with high-fat meals for adequate intesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03098cfc727b4d7611306e29a1feedcc
https://doi.org/10.1016/j.jacl.2012.01.002
https://doi.org/10.1016/j.jacl.2012.01.002
Autor:
Eli M. Roth, Kevin C. Maki, Douglas Kling, Judith Johnson, Michael H. Davidson, Stephen J. Nicholls, David G. Orloff, Richard L. Dunbar, Danielle Curcio
Publikováno v:
Lipids in Health and Disease
This study examined the effects of a mixture of highly bioavailable omega-3 carboxylic acids (OM3-CA) on nuclear magnetic resonance spectroscopy–assessed lipoprotein particle concentrations and sizes and other cardiovascular risk markers in statin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a2c5b96abe208a2c152999e71634ec
https://pubmed.ncbi.nlm.nih.gov/26328624
https://pubmed.ncbi.nlm.nih.gov/26328624
Publikováno v:
Clinical Therapeutics. 27:472-483
Gastroesophageal reflux disease (GERD), which is reflux that produces damage or troubling symptoms, afflicts approximately 7% of infants and children to the extent that administration of physician-directed pharmacotherapy is warranted.This study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f5b4c296f7f2709f08d3ac14bc879f
https://doi.org/10.1016/j.clinthera.2005.04.008
https://doi.org/10.1016/j.clinthera.2005.04.008