Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Douglas K. Marks"'
Autor:
Saeed Asiry, Gina Kim, Panagiota S. Filippou, Luis Rivera Sanchez, David Entenberg, Douglas K. Marks, Maja H. Oktay, George S. Karagiannis
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Although cancer immunotherapy has resulted in unpreceded survival benefits to subsets of oncology patients, accumulating evidence from preclinical animal models suggests that the immunosuppressive tumor microenvironment remains a detrimental factor l
Externí odkaz:
https://doaj.org/article/b6fcffab39034080abd5e2ff4e5604b0
Autor:
Douglas K. Marks, Robyn D. Gartrell, Margueritta El Asmar, Shuobo Boboila, Thomas Hart, Yan Lu, Qingfei Pan, Jiyang Yu, Hanina Hibshoosh, Hua Guo, Eleni Andreopoulou, Lisa Wiechmann, Katherine Crew, Joseph Sparano, Dawn Hershman, Eileen Connolly, Yvonne Saenger, Kevin Kalinsky
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: The PI3K/Akt/mTOR pathway in part impacts tumorigenesis through modulation of host immune activity. To assess the effects of Akt inhibition on the tumor micro-environment (TME), we analyzed tumor tissue from patients with operable hormone
Externí odkaz:
https://doaj.org/article/161752bec1d44d66a615bab9381ecca5
Autor:
Zoë Blake, Douglas K. Marks, Robyn D. Gartrell, Thomas Hart, Patti Horton, Simon K. Cheng, Bret Taback, Basil A. Horst, Yvonne M. Saenger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-8 (2018)
Abstract Background Immunotherapy, in particular checkpoint blockade, has changed the clinical landscape of metastatic melanoma. Nonetheless, the majority of patients will either be primary refractory or progress over follow up. Management of patient
Externí odkaz:
https://doaj.org/article/ce9cafdbc306493f8df22ea995ddb16b
Autor:
Yvonne M. Saenger, Basil A. Horst, Charles G. Drake, Howard L. Kaufman, Raul Rabadan, Bret Taback, Daisuke Izaki, Yichun Fu, Paul M. Armenta, Dan Tong Jia, Edward C. Stack, Camden L. Esancy, Anthea Monod, Kayleigh N. Askin, Yan Lu, Zoë Blake, Alan Wu, Danielle R. Davari, Gen Li, Thomas D. Hart, Douglas K. Marks, Robyn D. Gartrell
Novel methods to analyze the tumor microenvironment (TME) are urgently needed to stratify melanoma patients for adjuvant immunotherapy. Tumor-infiltrating lymphocyte (TIL) analysis, by conventional pathologic methods, is predictive but is insufficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42beae5a158d90ff7dacb5eff247f2cf
https://doi.org/10.1158/2326-6066.c.6549146.v1
https://doi.org/10.1158/2326-6066.c.6549146.v1
Autor:
Yvonne M. Saenger, Basil A. Horst, Charles G. Drake, Howard L. Kaufman, Raul Rabadan, Bret Taback, Daisuke Izaki, Yichun Fu, Paul M. Armenta, Dan Tong Jia, Edward C. Stack, Camden L. Esancy, Anthea Monod, Kayleigh N. Askin, Yan Lu, Zoë Blake, Alan Wu, Danielle R. Davari, Gen Li, Thomas D. Hart, Douglas K. Marks, Robyn D. Gartrell
Supplementary Pearson Correlation Matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c023e62ffb8fc824fcd84e972b31ec1
https://doi.org/10.1158/2326-6066.22539620.v1
https://doi.org/10.1158/2326-6066.22539620.v1
Autor:
Yvonne M. Saenger, Basil A. Horst, Charles G. Drake, Howard L. Kaufman, Raul Rabadan, Bret Taback, Daisuke Izaki, Yichun Fu, Paul M. Armenta, Dan Tong Jia, Edward C. Stack, Camden L. Esancy, Anthea Monod, Kayleigh N. Askin, Yan Lu, Zoë Blake, Alan Wu, Danielle R. Davari, Gen Li, Thomas D. Hart, Douglas K. Marks, Robyn D. Gartrell
Supplemental Figure 1: Flow chart for database Supplemental Figure 2: Representation of Tissue segmentation Supplemental Figure 3: Representation of Cell Segmentation Supplemental Figure 4: Representation of Phenotyping Supplemental Figure 5: Represe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d81878843938f047a8d94814d057cc1
https://doi.org/10.1158/2326-6066.22539632.v1
https://doi.org/10.1158/2326-6066.22539632.v1
Autor:
Yvonne M. Saenger, Basil A. Horst, Charles G. Drake, Howard L. Kaufman, Raul Rabadan, Bret Taback, Daisuke Izaki, Yichun Fu, Paul M. Armenta, Dan Tong Jia, Edward C. Stack, Camden L. Esancy, Anthea Monod, Kayleigh N. Askin, Yan Lu, Zoë Blake, Alan Wu, Danielle R. Davari, Gen Li, Thomas D. Hart, Douglas K. Marks, Robyn D. Gartrell
Demographics for DSS Cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a368cb62fc3dc1dc14ce6bc50d014b08
https://doi.org/10.1158/2326-6066.22539626.v1
https://doi.org/10.1158/2326-6066.22539626.v1
Autor:
Yvonne M. Saenger, Basil A. Horst, Carl Morrison, John J. Krolewski, Sandra J. Lee, Rui Chang, Sarabjot Pabla, Bret Taback, Marc S. Ernstoff, Shumin Rui, Jiayi Ji, Gen Li, Camden L. Esancy, Yichun Fu, Luke W. Barker, Camille L. Gérard, Margaret Bogardus, Emanuelle M. Rizk, Douglas K. Marks, Robyn D. Gartrell
Heat map showing relative levels of mRNA expression for each gene, specifying the gene represented by each row.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be00bc956cd694bb153046e45bf6f071
https://doi.org/10.1158/1078-0432.22472880
https://doi.org/10.1158/1078-0432.22472880
Autor:
Yvonne M. Saenger, Basil A. Horst, Carl Morrison, John J. Krolewski, Sandra J. Lee, Rui Chang, Sarabjot Pabla, Bret Taback, Marc S. Ernstoff, Shumin Rui, Jiayi Ji, Gen Li, Camden L. Esancy, Yichun Fu, Luke W. Barker, Camille L. Gérard, Margaret Bogardus, Emanuelle M. Rizk, Douglas K. Marks, Robyn D. Gartrell
Comparison of patient demographics in validation cohort to original publication discovery and test cohorts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05514166efd35e053c032d34da3689ff
https://doi.org/10.1158/1078-0432.22472871
https://doi.org/10.1158/1078-0432.22472871
Autor:
Yvonne M. Saenger, Basil A. Horst, Carl Morrison, John J. Krolewski, Sandra J. Lee, Rui Chang, Sarabjot Pabla, Bret Taback, Marc S. Ernstoff, Shumin Rui, Jiayi Ji, Gen Li, Camden L. Esancy, Yichun Fu, Luke W. Barker, Camille L. Gérard, Margaret Bogardus, Emanuelle M. Rizk, Douglas K. Marks, Robyn D. Gartrell
Figure legends for supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c5a088e73f90725938061a98db9071
https://doi.org/10.1158/1078-0432.22472874
https://doi.org/10.1158/1078-0432.22472874