Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Douglas K Bowles"'
Autor:
Govindaraj Anumanthan, Suneel Gupta, Michael K Fink, Nathan P Hesemann, Douglas K Bowles, Lindsey M McDaniel, Maaz Muhammad, Rajiv R Mohan
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0192145 (2018)
Vision impairment from corneal fibrosis is a common consequence of irregular corneal wound healing after injury. Intermediate-conductance calmodulin/calcium-activated K+ channels 3.1 (KCa3.1) play an important role in cell cycle progression and cellu
Externí odkaz:
https://doaj.org/article/4b4c2c43145342f8b201b4ba70b3f42d
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105337 (2014)
NADPH oxidase (NOX) is the primary source of reactive oxygen species (ROS) in vascular smooth muscle cells (SMC) and is proposed to play a key role in redox signaling involved in the pathogenesis of cardiovascular disease. Growth factors and cytokine
Externí odkaz:
https://doaj.org/article/578e2276323c4cb9b5bc7838000bafcf
Autor:
Darla L. Tharp, Douglas K. Bowles
Publikováno v:
Artery Research, Vol 27, Iss 2 (2021)
Low, oscillatory flow/shear patterns are associated with atherosclerotic lesion development. Increased expression of KCa3.1 has been found in Vascular Smooth Muscle (VSM), macrophages and T-cells in lesions from humans and mice. Increased expression
Externí odkaz:
https://doaj.org/article/5c3d0098be244a92bd5687b3c4948f48
Autor:
Darla L, Tharp, Douglas K, Bowles
Publikováno v:
Artery research
Low, oscillatory flow/shear patterns are associated with atherosclerotic lesion development. Increased expression of KCa3.1 has been found in Vascular Smooth Muscle (VSM), macrophages and T-cells in lesions from humans and mice. Increased expression
Autor:
Shawn B. Bender, Bysani Chandrasekar, Douglas K. Bowles, Maloree Khan, Alex Meuth, Scott Brown
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 317:H357-H363
Elevated plasma aldosterone (Aldo) levels are associated with greater risk of cardiac ischemic events and cardiovascular mortality. Adenosine-mediated coronary vasodilation is a critical cardioprotective mechanism during ischemia; however, whether th
Autor:
Gregory M. Dick, Shawn B. Bender, Chastidy A. Bailey, Adam G. Goodwill, Aaron J. Trask, Joshua J. Man, Bianca S. Blaettner, Douglas K. Bowles, Hana E. Baker, Darla L. Tharp, Johnathan D. Tune, Hannah E. Clark, Patricia E. McCallinhart, Iris Z. Jaffe, Scott M. Brown
Publikováno v:
Basic Research in Cardiology. 116
Impaired coronary microvascular function (e.g., reduced dilation and coronary flow reserve) predicts cardiac mortality in obesity, yet underlying mechanisms and potential therapeutic strategies remain poorly understood. Mineralocorticoid receptor (MR
Autor:
Darla L. Tharp, Patrice Delafontaine, James Jenkins, Daniel Garcia, Traci T. Goodchild, Douglas K. Bowles, Ina Nikolli, Thomas E. Sharp, Sergiy Sukhanov, Amy Scarborough, Jeffrey Schumacher, Mitzi Alfortish, Jan R. Ivey, David J. Lefer, Yusuke Higashi, Svitlana Danchuk
Publikováno v:
The FASEB Journal. 35
Autor:
Darla L. Tharp, Adam G. Goodwill, Gregory Dick, Patricia E. McCallinhart, Chastidy A. Bailey, Shawn B. Bender, Hana E. Baker, Aaron J. Trask, Joshua J. Man, Johnathan D. Tune, Douglas K. Bowles, Iris Z. Jaffe
Publikováno v:
The FASEB Journal. 35
Autor:
Adam G, Goodwill, Hana E, Baker, Gregory M, Dick, Patricia E, McCallinhart, Chastidy A, Bailey, Scott M, Brown, Joshua J, Man, Darla L, Tharp, Hannah E, Clark, Bianca S, Blaettner, Iris Z, Jaffe, Douglas K, Bowles, Aaron J, Trask, Johnathan D, Tune, Shawn B, Bender
Publikováno v:
Basic Res Cardiol
Impaired coronary microvascular function (e.g., reduced dilation and coronary flow reserve) predicts cardiac mortality in obesity, yet underlying mechanisms and potential therapeutic strategies remain poorly understood. Mineralocorticoid receptor (MR
Aldosterone impairs coronary adenosine-mediated vasodilation via reduced functional expression of Ca
Autor:
Maloree, Khan, Alex I, Meuth, Scott M, Brown, Bysani, Chandrasekar, Douglas K, Bowles, Shawn B, Bender
Publikováno v:
Am J Physiol Heart Circ Physiol
Elevated plasma aldosterone (Aldo) levels are associated with greater risk of cardiac ischemic events and cardiovascular mortality. Adenosine-mediated coronary vasodilation is a critical cardioprotective mechanism during ischemia; however, whether th