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pro vyhledávání: '"Douglas James Critcher"'
Autor:
Fiona L. Rawlinson, Jones Matthew Cameron, Steven J. Fussell, John Pearce, Robert Walton, Clare L. Crook, Nieves Castro, Douglas James Critcher, Alexandra E. Sherlock, Lynne McMillan, Matthew Badland, Katherine J. Jones, E. Kougoulos, Adam T. Gillmore, Jinu S. Mathew
Publikováno v:
Organic Process Research & Development. 16:1897-1904
Novel PARP inhibitor 1 is a promising new candidate for treatment of breast and ovarian cancer. A modified synthetic route to 1 has been developed and demonstrated on 7 kg scale. In order to scale up the synthesis to multikilogram scale, several synt