Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Douglas J. Schwartzentruber"'
Autor:
Ryan J. Sullivan, Douglas J. Schwartzentruber, Michael B. Atkins, John M. Kirkwood, John B. A. G. Haanen
Publikováno v:
Cutaneous Melanoma ISBN: 9783319460291
Cutaneous Melanoma
Cutaneous Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26818a4599cc3117bb711695a3581583
https://doi.org/10.1007/978-3-030-05070-2_56
https://doi.org/10.1007/978-3-030-05070-2_56
Autor:
Kim M. Keppler-Noreuil, B. Maya Kato, James C. Mullikin, Catherine Blumhorst, Marjorie J. Lindhurst, Kimberly Hoag, Kevin O'Brien, Jennifer L. Cannons, Natasha Cherman, David Ng, Jennifer J. Johnston, Sergei A. Kuznetsov, Julie C Sapp, Thomas N. Darling, Steven S. Rothenberg, Roberto Tirabosco, Shlomo Wientroub, Elaine H. Zackai, Virender Singhal, Laurel C Blakemore, Matthew A. Deardorff, Pamela Gehron Robey, Kurt D. Newman, David B. Everman, Peter Calder, Joseph Upton, Douglas J. Schwartzentruber, Joyce T. Turner, Richard T. Miyamoto, Laura L. Tosi, Knut Brockmann, Tracey Whitewood-Neal, Gretchen Golas, Robert M. Greenstein, Leslie G. Biesecker, Kathryn F. Peters, Pamela L. Schwartzberg, Jamie K. Teer, David P. Bick, Erin M Finn
Publikováno v:
New England Journal of Medicine. 365:611-619
A b s t r ac t Background The Proteus syndrome is characterized by the overgrowth of skin, connective tissue, brain, and other tissues. It has been hypothesized that the syndrome is caused by somatic mosaicism for a mutation that is lethal in the non
Autor:
Jonathan S. Treisman, Phillip D. Leming, Richard L. White, Peter L. Choyke, Donald M. Miller, Kevin C. Conlon, Francesco M. Marincola, David H. Lawson, Timothy M. Kuzel, Eric D. Whitman, Robert M. Conry, Jon M. Richards, Rene Gonzalez, Kari Kendra, Steven A. Rosenberg, Howard L. Kaufman, Douglas S. Reintgen, Fawaz Gailani, Brendan D. Curti, Don Vena, Barbara A. Pockaj, Jai Balkissoon, Maria J. Merino, Patrick Hwu, Douglas J. Schwartzentruber, Lee B. Riley
Publikováno v:
New England Journal of Medicine. 364:2119-2127
Stimulating an immune response against cancer with the use of vaccines remains a challenge. We hypothesized that combining a melanoma vaccine with interleukin-2, an immune activating agent, could improve outcomes. In a previous phase 2 study, patient
Autor:
Amikar Sehdev, Simon J. Warren, Ross Hayden, Theodore F. Logan, William Arthur Wooden, Mathew Joseph Kuhar, Liang Cheng, Douglas J. Schwartzentruber, Lawrence Aaron Mark
Publikováno v:
Journal of Clinical Oncology. 36:e21599-e21599
e21599Background: Prognostic role of BRAF mutation is not well-studied in malignant cutaneous melanoma. We conducted a large retrospective study using a state-wide database to assess the clinical c...
Autor:
Anthon R. Fuisz, Katherine R. Calvo, Douglas R. Rosing, W. Patricia Ingkanisorn, Douglas J. Schwartzentruber, D. Ian Paterson, Andrew E. Arai
Publikováno v:
Journal of Cardiovascular Magnetic Resonance. 8:353-360
The purpose of this study was to describe and compare the cardiac magnetic resonance (CMR) characteristics of myocarditis caused by high dose interleukin-2 (7 patients) with community-acquired myocarditis (14 patients). A total of 21 patients with su
Autor:
James N. Lowder, Howard L. Kaufman, Michael B. Atkins, Sanjiv S. Agarwala, Janice P. Dutcher, Douglas J. Schwartzentruber, Ahmad A. Tarhini
Publikováno v:
Journal for Immunotherapy of Cancer
Interleukin-2 (IL-2) was historically one of the few treatments for adults with stage IV solid tumors that could produce complete responses (CRs) that were often durable for decades without further therapy. The majority of complete responders with me
Autor:
Udai S. Kammula, Seth M. Steinberg, Sharon Mavroukakis, Steven A. Rosenberg, Suzanne L. Topalian, Lien T. Ngo, David Berman, Richard M. Sherry, William J. Scharfman, Susan L. Schwarz, Donald E. White, Douglas J. Schwartzentruber, Nicholas P. Restifo, Michael S. Hughes, Richard E. Royal, James Chih-Hsin Yang, Kathleen E. Morton
Publikováno v:
The Journal of Immunology. 175:6169-6176
The identification of many tumor-associated epitopes as nonmutated “self” Ags led to the hypothesis that the induction of large numbers of self/tumor Ag-specific T cells would be prevented because of central and peripheral tolerance. We report in
Autor:
Sandra Snow, Dean S. McGaughey, Barry L. Gause, Jon P. Gockerman, Elizabeth C. Jones, Thomas P. Loughran, Ken Takeshita, Thelma M. Watson, Elaine S. Jaffe, Erik Kass, Larry W. Kwak, David N. Danforth, Stephen J. Schuster, Craig W. Reynolds, Miriam Ferraro, Douglas J. Schwartzentruber, Paula Kubovic, Daniel A. Nikcevich, Jane N. Winter, Richard M. Sherry, Giorgio Inghirami, Carter Van Waes, Sattva S. Neelapu
Publikováno v:
Clinical Lymphoma. 6:61-64
We translated these laboratory findings to a single-arm, phaseII clinical study in which patients with previously untreatedstage III/IV follicular lymphoma were initially treated intominimal residual disease (MRD) state with a uniformchemotherapy reg
Autor:
Richard Chang, Paul F. Robbins, Nicholas P. Restifo, Patrick Hwu, Steven A. Rosenberg, John R. Wunderlich, Suzanne L. Topalian, James Chih-Hsin Yang, Douglas J. Schwartzentruber, Richard M. Sherry, Armando C. Filie, Mark E. Dudley
Publikováno v:
Journal of Immunotherapy. 26:385-393
The development of effective autologous cell transfer therapies for the treatment of patients with cancer has been difficult, in part because the cells used to treat each patient are different, as are the patient’s tumor and immune status. Much can
Publikováno v:
Seminars in Oncology Nursing. 19:206-216
To provide a review of cancer vaccines, how they work, and the current state of the science underlying these treatments.Research studies, review articles, book chapters, personal communications.Vaccines have been studied in a variety of malignancies;