Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Douglas J. Dorahy"'
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure
Externí odkaz:
https://doaj.org/article/6629ebd3dc40409fb48c842520d50755
Autor:
Koliarne Tong, Claire E. Wainwright, Peter G. Middleton, Hugh Greville, Douglas J. Dorahy, Daniel Barker, Peter A. B. Wark, Lucy D. Burr, Simone K. Visser
Publikováno v:
Journal of Cystic Fibrosis. 19:415-420
Lumacaftor/ivacaftor (LUM/IVA) improves outcomes in cystic fibrosis (CF) patients homozygous for Phe508del with ppFEV140%. There is limited safety or efficacy data in patients with ppFEV140%. We determined whether LUM/IVA in patients with ppFEV140 wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab5285e3bcf4c447ade4c177183c2c3
https://doi.org/10.1016/j.jcf.2019.12.006
https://doi.org/10.1016/j.jcf.2019.12.006
Publikováno v:
Allergy and immunology.
Introduction and Aim: Severe asthma is characterised by frequent exacerbations with the majority triggered by viral infections. Treatment of severe allergic asthma with Omalizumab reduces exacerbation risk. We sought to determine how Omalizumab impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7492cad2517d510301b4d8bfb1b5d4a3
https://doi.org/10.1183/13993003.congress-2019.pa534
https://doi.org/10.1183/13993003.congress-2019.pa534
Publikováno v:
BMC Pulmonary Medicine
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-8 (2019)
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-8 (2019)
Background Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure that woul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560c1bf50191fe2f2a7e58898f30d553
https://pubmed.ncbi.nlm.nih.gov/31208380
https://pubmed.ncbi.nlm.nih.gov/31208380
Autor:
Mark R. Elkins, Peter A. B. Wark, Honghua Hu, Christopher J. Harmer, Peter G. Middleton, Ruth Dentice, Peter T. P. Bye, Jennifer Bishop, Douglas J. Dorahy
Publikováno v:
Thorax. 71(2)
Background The mucoactive effects of hypertonic saline should promote exacerbation resolution in people with cystic fibrosis (CF). Objectives To determine the effects of hypertonic saline inhalation during hospitalisation for exacerbation of CF on le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fe1f1129fd75421a7ff55e3800f6d6c
https://pubmed.ncbi.nlm.nih.gov/26769012
https://pubmed.ncbi.nlm.nih.gov/26769012
Publikováno v:
Journal of Cancer Therapy. :295-301
Background: It is known that active Src kinase promotes survival of ovarian cancer cell lines and inhibition of c-Src has been shown to restore sensitivity of drug-resistant human ovarian cancer cells to cisplatin. In this study we examined the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00276c7770ea2072f36fe4de093aa0db
https://doi.org/10.4236/jct.2011.23039
https://doi.org/10.4236/jct.2011.23039
Publikováno v:
Journal of Cystic Fibrosis. 17:S56
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e463bcd0ba9d0af5387469b68f83c18
https://doi.org/10.1016/s1569-1993(18)30293-5
https://doi.org/10.1016/s1569-1993(18)30293-5
Autor:
Wieland Meyer, Michelle Wood, Graeme R. Nimmo, Peter G. Middleton, Narelle George, Claire E. Wainwright, Peter Cooper, H. Saddington, Scott C. Bell, Shuyao Duan, Peter A. B. Wark, Hugh Greville, Karen McKay, Shilpa Patel, Sarah E. Kidd, Sally Chapman, Douglas J. Dorahy, Tania C. Sorrell, Sharon C.-A. Chen, Belinda Chapman, Joyce Cheney
Publikováno v:
Open Forum Infectious Diseases. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f93df57065088c6b10a03a41efaaee6c
https://doi.org/10.1093/ofid/ofv133.1373
https://doi.org/10.1093/ofid/ofv133.1373
Autor:
Michael Agrez, Nuzhat Ahmed, Mark S. Baker, Jun Niu, Sarah Andrews, Ian Macreadie, Rodney J. Scott, Douglas J. Dorahy, Cliff Meldrum, Xinhua Gu
Publikováno v:
Oncogene. 21:1370-1380
Blockade of the mitogen-activated protein (MAP) kinase pathway suppresses growth of colon cancer in vivo. Here we demonstrate a direct link between the extracellular signal-regulated kinase ERK2 and the growth-promoting cell adhesion molecule, integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52428c7080c2ae35b345b1194a7cfe3a
https://doi.org/10.1038/sj.onc.1205286
https://doi.org/10.1038/sj.onc.1205286
Publikováno v:
Journal of General Virology. 81:889-894
Coxsackievirus A21 (CAV-21) employs a cell receptor complex of decay-accelerating factor (DAF) and intercellular adhesion molecule-1 (ICAM-1) for cell infectivity. In this study, the nature of potential extra- and/or intracellular interactions betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5d7ccc2551ecfb996d0c6eaf275a15
https://doi.org/10.1099/0022-1317-81-4-889
https://doi.org/10.1099/0022-1317-81-4-889