Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Douglas J. Brusich"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Homeostatic synaptic plasticity (HSP) helps neurons and synapses maintain physiologically appropriate levels of output. The fruit fly Drosophila melanogaster larval neuromuscular junction (NMJ) is a valuable model for studying HSP. Here we introduce
Externí odkaz:
https://doaj.org/article/9487d52b91fc43729d63e46ea0f2e1b9
Publikováno v:
Fly, Vol 13, Iss 1-4, Pp 1-11 (2019)
Several million traumatic brain injury (TBI) events are reported in the United States annually. However, mild TBI events often go unreported, and mild and repetitive mild TBI conditions are challenging to model. Fruit flies (Drosophila melanogaster)
Externí odkaz:
https://doaj.org/article/519240ecc813424a8906f394eb13329c
Traumatic brain injury (TBI) is common and often debilitating. One complication following TBI is post-traumatic seizures (PTS). However, there is a poor understanding of PTS, in part, because it is challenging to model. We sought to develop a fly mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1beaf92726eae6195eae00b125b14d36
https://doi.org/10.1101/2021.10.26.465914
https://doi.org/10.1101/2021.10.26.465914
Autor:
Douglas J Brusich, Thomas D. James, Ashlyn M. Spring, Timothy H. Helms, C. Andrew Frank, Catherine J. Yeates
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afa289e63554deee5d9ba76c598891a6
https://doi.org/10.1101/141366
https://doi.org/10.1101/141366
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005886 (2016)
PLoS Genetics
PLoS Genetics
Forms of homeostatic plasticity stabilize neuronal outputs and promote physiologically favorable synapse function. A well-studied homeostatic system operates at the Drosophila melanogaster larval neuromuscular junction (NMJ). At the NMJ, impairment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3314bc1d32895dfc6c18e68bb8172a9b
http://europepmc.org/articles/PMC4764653?pdf=render
http://europepmc.org/articles/PMC4764653?pdf=render
Autor:
C. Andrew Frank, Ashlyn M. Spring, Douglas J. Brusich, Timothy H. Helms, Thomas D. James, Catherine J. Yeates
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9927de23c394e9c5fcc523b87ea75189
https://doi.org/10.1371/journal.pgen.1007577
https://doi.org/10.1371/journal.pgen.1007577
Autor:
Douglas J Brusich, Ashlyn M Spring, Thomas D James, Catherine J Yeates, Timothy H Helms, C Andrew Frank
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://doaj.org/article/8e84afdcc7674cc9a7d61507fc3ce816
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005886 (2016)
Forms of homeostatic plasticity stabilize neuronal outputs and promote physiologically favorable synapse function. A well-studied homeostatic system operates at the Drosophila melanogaster larval neuromuscular junction (NMJ). At the NMJ, impairment o
Externí odkaz:
https://doaj.org/article/81e0230539fd4423b895b36ce8a1600e