Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Douglas J Conrad"'
Autor:
Douglas J Conrad, Barbara A Bailey, Jon A Hardie, Per S Bakke, Tomas M L Eagan, Bernt B Aarli
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190061 (2017)
Clinical phenotyping, therapeutic investigations as well as genomic, airway secretion metabolomic and metagenomic investigations can benefit from robust, nonlinear modeling of FEV1 in individual subjects. We demonstrate the utility of measuring FEV1
Externí odkaz:
https://doaj.org/article/a9b07389cc294233a6d9cbf5e1a39af0
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157177 (2016)
Translational investigations in cystic fibrosis (CF) have a need for improved quantitative and longitudinal measures of disease status. To establish a non-invasive quantitative MRI technique to monitor lung health in patients with CF and correlate MR
Externí odkaz:
https://doaj.org/article/3a66c7672eb947a08844d1568af64dd9
Autor:
Douglas J Conrad, Barbara A Bailey
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122705 (2015)
Cystic Fibrosis (CF) is a multi-systemic disease resulting from mutations in the Cystic Fibrosis Transmembrane Regulator (CFTR) gene and has major manifestations in the sino-pulmonary, and gastro-intestinal tracts. Clinical phenotypes were generated
Externí odkaz:
https://doaj.org/article/d436694650ca46969e25310adb07afc3
Autor:
Michael Sveiven, Ana K. Serrano, Joshua Rosenberg, Douglas J. Conrad, Drew A. Hall, Anthony J. O’Donoghue
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Hydrolytic enzymes play crucial roles in cellular processes, and dysregulation of their activities is implicated in various physiological and pathological conditions. These enzymes cleave substrates such as peptide bonds, phosphodiester bonds, glycos
Externí odkaz:
https://doaj.org/article/3381328e55a7414eac211cc26e255b75
Autor:
Ana Georgina Cobián Güemes, Tram Le, Maria Isabel Rojas, Nicole E. Jacobson, Helena Villela, Katelyn McNair, Shr-Hau Hung, Lili Han, Lance Boling, Jessica Claire Octavio, Lorena Dominguez, Vito Adrian Cantú, Sinéad Archdeacon, Alejandro A. Vega, Michelle A. An, Hamza Hajama, Gregory Burkeen, Robert A. Edwards, Douglas J. Conrad, Forest Rohwer, Anca M. Segall
Publikováno v:
Viruses, Vol 15, Iss 8, p 1665 (2023)
Achromobacter species colonization of Cystic Fibrosis respiratory airways is an increasing concern. Two adult patients with Cystic Fibrosis colonized by Achromobacter xylosoxidans CF418 or Achromobacter ruhlandii CF116 experienced fatal exacerbations
Externí odkaz:
https://doaj.org/article/753f2a6a9ed8459290dca446b65ac621
Autor:
Neena R. Iyer, Kamyar Afshar, Jisha Joshua, Eugene Golts, Gordon L. Yung, Aarya Kafi, Douglas J. Conrad, David C. Kunkel
Publikováno v:
Foregut: The Journal of the American Foregut Society. 3:12-19
Background: Esophageal inlet patch (IP) refers to heterotopic gastric mucosa in the cervical esophagus. Secretions from IP may produce symptoms of laryngopharyngeal reflux (LPR) and accelerate progression of lung disease. We aimed to characterize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ccd636be17771ac430006d2c39ff52
https://doi.org/10.1177/26345161221131985
https://doi.org/10.1177/26345161221131985
Autor:
Alexey V. Melnik, Yoshiki Vázquez-Baeza, Alexander A. Aksenov, Embriette Hyde, Andrew C. McAvoy, Mingxun Wang, Ricardo R. da Silva, Ivan Protsyuk, Jason V. Wu, Amina Bouslimani, Yan Wei Lim, Tal Luzzatto-Knaan, William Comstock, Robert A. Quinn, Richard Wong, Greg Humphrey, Gail Ackermann, Timothy Spivey, Sharon S. Brouha, Nuno Bandeira, Grace Y. Lin, Forest Rohwer, Douglas J. Conrad, Theodore Alexandrov, Rob Knight, Pieter C. Dorrestein, Neha Garg
Publikováno v:
mSystems, Vol 4, Iss 5 (2019)
ABSTRACT To visualize the personalized distributions of pathogens and chemical environments, including microbial metabolites, pharmaceuticals, and their metabolic products, within and between human lungs afflicted with cystic fibrosis (CF), we genera
Externí odkaz:
https://doaj.org/article/52f7a097d5b64c42bd3fbf8ea662a647
Autor:
Ana Georgina Cobián Güemes, Yan Wei Lim, Robert A. Quinn, Douglas J. Conrad, Sean Benler, Heather Maughan, Rob Edwards, Thomas Brettin, Vito Adrian Cantú, Daniel Cuevas, Rohaum Hamidi, Pieter Dorrestein, Forest Rohwer
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT Pulmonary exacerbations are the leading cause of death in cystic fibrosis (CF) patients. To track microbial dynamics during acute exacerbations, a CF rapid response (CFRR) strategy was developed. The CFRR relies on viromics, metagenomics, me
Externí odkaz:
https://doaj.org/article/a2d51f7ea3ee43cc9a4512176910b72f
The continued inclusion of race in spirometry reference equations is a topic of intense debate for adult lung function, but less discussion has focused on implications for children. Obtaining accurate estimates of children's lung function is an impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff36af4e12bdbe2b789f72dc51927a12
https://escholarship.org/uc/item/1hc8v8tx
https://escholarship.org/uc/item/1hc8v8tx
Autor:
Elizabeth A. Regan, Melissa E. Lowe, Barry J. Make, Jeffrey L. Curtis, Quan Chen, Michael H. Cho, James L. Crooks, Katherine E. Lowe, Carla Wilson, James K. O’Brien, Gabriela R. Oates, Arianne K. Baldomero, Gregory L. Kinney, Kendra A. Young, Alejandro A. Diaz, Surya P. Bhatt, Meredith C. McCormack, Nadia N. Hansel, Victor Kim, Nicole E. Richmond, Gloria E. Westney, Marilyn G. Foreman, Douglas J. Conrad, Dawn L. DeMeo, Karin F. Hoth, Hannatu Amaza, Aparna Balasubramanian, Julia Kallet, Shandi Watts, Nicola A. Hanania, John Hokanson, Terri H. Beaty, James D. Crapo, Edwin K. Silverman, Richard Casaburi, Robert Wise
Publikováno v:
Journal of General Internal Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c608fc8cb71ca382bb308b13ae2074
https://doi.org/10.1007/s11606-023-08185-5
https://doi.org/10.1007/s11606-023-08185-5