Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Douglas H, Lester"'
Autor:
Hemanth Tummala, Hilal S Khalil, Mohammad R. Islam, Sarah J. Jones, Ian R. Ellis, Isabella D’Ascanio, Nikolai Zhelev, Douglas H. Lester
Publikováno v:
BioDiscovery, Vol 9, Iss , Pp 1-22 (2013)
It has recently been reported that the duplication of the GNB3 gene has been shown to be directly linked to an obesity phenotype, both in humans and also in a humanised mouse model. Moreover, the common human GNB3 c.825C>T polymorphism (rs5443) cause
Externí odkaz:
https://doaj.org/article/a0c4c466a85749dfbd6fb55821fddb50
Autor:
Hemanth Tummala, Stewart Fleming, Paul M Hocking, Daniel Wehner, Zahid Naseem, Manir Ali, Christopher F Inglehearn, Nikolai Zhelev, Douglas H Lester
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e21156 (2011)
The GNB3 gene is expressed in cone but not rod photoreceptors of vertebrates, where it acts as the β transducin subunit in the colour visual transduction process. A naturally occurring mutation 'D153del' in the GNB3 gene causes the recessively inher
Externí odkaz:
https://doaj.org/article/fa68b5aa901446e5bb7a675c3e50e04a
Publikováno v:
Nucleic Acid Therapeutics. 26:257-265
The very common GNB3 c.825CT polymorphism (rs5443) is present in approximately half of all human chromosomes. Significantly, the presence of the GNB3 825T allele has been strongly associated with predisposition to essential hypertension. Paradoxicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17545ad7f08261cc1457583618d1778e
https://doi.org/10.1089/nat.2015.0571
https://doi.org/10.1089/nat.2015.0571
Autor:
Sean G, Brown, Melissa R, Miller, Polina V, Lishko, Douglas H, Lester, Stephen J, Publicover, Christopher L R, Barratt, Sarah, Martins Da Silva
Publikováno v:
Human Reproduction (Oxford, England)
STUDY QUESTION Does a man (patient 1) with a previously described deficiency in principle cation channel of sperm (CatSper) function have a mutation in the CatSper-epsilon (CATSPERE) and/or CatSper-zeta (CATSPERZ) gene? SUMMARY ANSWER Patient 1 has a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12927d5ddb8dd6f4483f3dfe2e6260ba
https://pubmed.ncbi.nlm.nih.gov/30239785
https://pubmed.ncbi.nlm.nih.gov/30239785
Autor:
Sarah J. Jones, Douglas H. Lester, Mohammad Islam, Isabella D’Ascanio, Hemanth Tummala, Ian R. Ellis, Nikolai Zhelev, Hilal S. Khalil
Publikováno v:
BioDiscovery, Vol 9, Iss, Pp 1-22 (2013)
BioDiscovery 9: e8953
BioDiscovery 9: e8953
It has recently been reported that the duplication of the GNB3 gene has been shown to be directly linked to an obesity phenotype, both in humans and also in a humanised mouse model. Moreover, the common human GNB3 c.825C>T polymorphism (rs5443) cause
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ab1edad189625a71237bf9251b10fc
https://biodiscovery.pensoft.net/article/8953/
https://biodiscovery.pensoft.net/article/8953/
Autor:
Paul Hocking, Douglas H. Lester, Hemanth Tummala, Manir Ali, Chris F. Inglehearn, Paul Getty, David W. Burt
Publikováno v:
Genetical Research. 89:181-188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a05354b685b91123354848083c04fe6
https://doi.org/10.1017/s0016672307008804
https://doi.org/10.1017/s0016672307008804
Publikováno v:
Biochemical and Biophysical Research Communications. 269:474-480
Ubiquitin-conjugating enzymes (UBCs) selectively target proteins for proteasomal degradation by the covalent attachment of ubiquitin moieties. Yeast UBC6 is unusual in having an active site distinct from all other UBCs and in possessing a transmembra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c722a4452661dab62b0d99b85c5097
https://doi.org/10.1006/bbrc.2000.2302
https://doi.org/10.1006/bbrc.2000.2302
Autor:
David W. Burt, Ian R. Paton, Elaine Seawright, David Jefferies, Brian Houston, C. C. Whitehead, Douglas H. Lester, Colin Farquharson
Publikováno v:
Animal Genetics. 30:300-303
The growth plate is a specialised region of cartilage located at the growing ends of long bones in higher vertebrates. It is responsible for longitudinal bone growth and is under the control of many local and systemic factors. The growth plate consis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b705b7ada0ce635783ee4447bbf194f
https://doi.org/10.1046/j.1365-2052.1999.00473.x
https://doi.org/10.1046/j.1365-2052.1999.00473.x
Autor:
Douglas H. Lester, Colin Farquharson, Elaine Seawright, David Jefferies, C C Whitehead, Esther Hoogland, Brian Houston
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1448:500-506
Growth plate chondrocytes progress through a proliferative phase before acquiring a terminally-differentiated phenotype. In this study we used Percoll density gradients to separate chick growth plate chondrocytes into populations of different maturat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e821c9ef157a1aabafc9c08ae4c0bd
https://doi.org/10.1016/s0167-4889(98)00153-0
https://doi.org/10.1016/s0167-4889(98)00153-0
Publikováno v:
Genetical Research. 68:75-89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1c63b315d457bcdf02a8fa0f5f278b1
https://doi.org/10.1017/s0016672300033905
https://doi.org/10.1017/s0016672300033905