Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Douglas G, Tilley"'
Autor:
Xinji Guo, PhD, Mikhail A. Kolpakov, MD, PhD, Bahman Hooshdaran, PhD, William Schappell, BS, Tao Wang, MD, PhD, Satoru Eguchi, MD, PhD, Katherine J. Elliott, PhD, Douglas G. Tilley, PhD, A. Koneti Rao, MD, Patricia Andrade-Gordon, PhD, Matthew Bunce, PhD, Chintala Madhu, PhD, Steven R. Houser, PhD, Abdelkarim Sabri, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 1, Pp 69-83 (2020)
Summary: Activated factor X is a key component of the coagulation cascade, but whether it directly regulates pathological cardiac remodeling is unclear. In mice subjected to pressure overload stress, cardiac factor X mRNA expression and activity incr
Externí odkaz:
https://doaj.org/article/129e8e00131747649c682ca916df38a5
Autor:
Ama Dedo Okyere, Douglas G. Tilley
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Cardiac fibrosis begins as an intrinsic response to injury or ageing that functions to preserve the tissue from further damage. Fibrosis results from activated cardiac myofibroblasts, which secrete extracellular matrix (ECM) proteins in an effort to
Externí odkaz:
https://doaj.org/article/7d62e618f7674d1289c739c345bfe539
Publikováno v:
American journal of physiology. Cell physiology. 323(2)
G protein-coupled receptors (GPCRs) represent one of the most targeted drug classes in the human genome, accounting for greater than 40% of all Food and Drug Administration-approved drugs. However, the second-largest family of GPCRs, known as adhesio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4993923ddefa0752110190141d80aa1
https://pubmed.ncbi.nlm.nih.gov/35848619
https://pubmed.ncbi.nlm.nih.gov/35848619
Autor:
Heli Xu, Douglas G. Tilley
Publikováno v:
Journal of Cardiovascular Pharmacology. 80:378-385
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::679c9fd623a71f699039c3b2dc49bf10
https://doi.org/10.1097/fjc.0000000000001236
https://doi.org/10.1097/fjc.0000000000001236
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cardiovascular Pharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8579f28ec9a644631af26f48f4f27451
https://doi.org/10.1124/jpet.122.560610
https://doi.org/10.1124/jpet.122.560610
Autor:
Tijana Knezevic, PhD, Valerie D. Myers, MS, Feifei Su, MD, PhD, JuFang Wang, MD, Jianliang Song, MD, PhD, Xue-Qian Zhang, MD, Erhe Gao, MD, PhD, Guofeng Gao, MD, PhD, Muniswamy Madesh, PhD, Manish K. Gupta, PhD, Jennifer Gordon, PhD, Kristen N. Weiner, BS, Joseph Rabinowitz, PhD, Frederick V. Ramsey, PhD, Douglas G. Tilley, PhD, Kamel Khalili, PhD, Joseph Y. Cheung, MD, PhD, Arthur M. Feldman, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 647-656 (2016)
Mutations in Bcl-2–associated athanogene 3 (BAG3) were associated with skeletal muscle dysfunction and dilated cardiomyopathy. Retro-orbital injection of an adeno-associated virus serotype 9 expressing BAG3 (rAAV9-BAG3) significantly (p < 0.0001) i
Externí odkaz:
https://doaj.org/article/70f170720da34f2985f48ff26cb0cbfd
Autor:
Anamika Bajpai, Douglas G. Tilley
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Diabetes is predominant risk factor for cardiovascular diseases such as myocardial infarction and heart failure. Recently, leukocytes, particularly neutrophils, macrophages, and lymphocytes, have become targets of investigation for their potential ro
Externí odkaz:
https://doaj.org/article/7854943f343241308d9e52a0a299eb06
Autor:
Ama Dedo Okyere, Jianliang Song, Viren Patwa, Rhonda L. Carter, Nitya Enjamuri, Anna Maria Lucchese, Jessica Ibetti, Claudio de Lucia, Sarah M. Schumacher, Walter J. Koch, Joseph Y. Cheung, Jeffrey L. Benovic, Douglas G. Tilley
Publikováno v:
Cardiovascular Drugs and Therapy. 37:245-256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67520082a5b7402468cb8f6d30dff837
https://doi.org/10.1007/s10557-021-07299-4
https://doi.org/10.1007/s10557-021-07299-4
Autor:
Rhonda L. Carter, Erin McEachern, Joseph Y. Cheung, Jianliang Song, Ana Maria Lucchese, Erhe Gao, Douglas G. Tilley, Ama Dedo Okyere, Toby P. Thomas, Jonathan A. Kirk, Thomas G Martin, Viren C Patwa, Sudarsan Rajan, Joshua Strong, Melissa Landy, Shuchi Guo, Walter J. Koch
Publikováno v:
Cardiovasc Res
Aims Epidermal growth factor receptor (EGFR) is essential to the development of multiple tissues and organs and is a target of cancer therapeutics. Due to the embryonic lethality of global EGFR deletion and conflicting reports of cardiac-overexpresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf982914b87b2eb4dcc00e65bae765c
https://doi.org/10.1093/cvr/cvab149
https://doi.org/10.1093/cvr/cvab149
Autor:
Luciana M. Leo, Rufaida Al-Zoubi, Dow P. Hurst, Anna P. Stephan, Pingwei Zhao, Douglas G. Tilley, Elke Miess, Stefan Schulz, Mary E. Abood, Patricia H. Reggio
Publikováno v:
Cannabis and cannabinoid research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801b5c55b14222086b07ec6b63a1b618
https://pubmed.ncbi.nlm.nih.gov/35792570
https://pubmed.ncbi.nlm.nih.gov/35792570