Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Douglas G, Burrin"'
Autor:
Thora Wesenberg Helt, Lene Buelund, Lise Borgwardt, Thomas Eriksen, Lars Johansen, Robin de Nijs, Soren Holm, Douglas G. Burrin, Thomas Thymann, Vibeke Brix Christensen
Publikováno v:
Biochemistry and Biophysics Reports, Vol 34, Iss , Pp 101487- (2023)
Biliary atresia (BA) is a rare congenital liver disease with unknown etiology, and it is the most common indication for liver transplantation in children. As BA infants suffer from intestinal malabsorption and neurodevelopmental deficits, it is neces
Externí odkaz:
https://doaj.org/article/f62ee79acdbf447f9aef1d22ebbbbd7d
Autor:
Line I. Christiansen, Gemma C. Ventura, Bo Holmqvist, Karoline Aasmul-Olsen, Sandy E. H. Lindholm, Matthew D. Lycas, Yuki Mori, Jan Bojsen-Møller Secher, Douglas G. Burrin, Thomas Thymann, Per T. Sangild, Stanislava Pankratova
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionPreterm infants have increased risk of impaired neurodevelopment to which reduced systemic levels of insulin-like growth factor 1 (IGF-1) in the weeks after birth may play a role. Hence, we hypothesized that postnatal IGF-1 supplementatio
Externí odkaz:
https://doaj.org/article/4d8fb21ad86e4b09b1b873f04f6047ce
Publikováno v:
Biomedicines, Vol 11, Iss 12, p 3303 (2023)
The objective of this study was to investigate whether the impairment of farnesoid X receptor (FXR)-fibroblast growth factor 19 (FGF19) signaling in juvenile pigs with non-alcoholic fatty liver disease (NAFLD) is associated with changes in the compos
Externí odkaz:
https://doaj.org/article/4902969a4f9a4a218e6f4f85bb03dcb5
Autor:
Kristine Holgersen, Martin Bo Rasmussen, Galen Carey, Douglas G. Burrin, Thomas Thymann, Per Torp Sangild
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundElevation of circulating insulin-like growth factor-1 (IGF-1) within normal physiological levels may alleviate several morbidities in preterm infants but safety and efficacy remain unclear. We hypothesized that IGF-1 supplementation during
Externí odkaz:
https://doaj.org/article/c1e8930836474808827ff6da8557a1f9
Autor:
Nicole Lind Henriksen, Svend Høime Hansen, Matthew Domenic Lycas, Xiaoyu Pan, Thomas Eriksen, Lars Søndergaard Johansen, Richard R. Sprenger, Christer Stenby Ejsing, Douglas G. Burrin, Kerstin Skovgaard, Vibeke Brix Christensen, Thomas Thymann, Stanislava Pankratova
Publikováno v:
Physiological Reports, Vol 10, Iss 13, Pp n/a-n/a (2022)
Abstract Infants with neonatal cholestasis are prone to neurodevelopmental deficits, however, the underlying pathogenesis is unclear. Lipid malabsorption and accumulation of potentially neurotoxic molecules in the blood such as bile acids are importa
Externí odkaz:
https://doaj.org/article/aab40f1f653541c48ef750a8f0a429a6
Autor:
Valeria Melendez Hebib, Diana H. Taft, Barbara Stoll, Jinxin Liu, Lee Call, Gregory Guthrie, Nick Jensen, Amy B. Hair, David A. Mills, Douglas G. Burrin
Publikováno v:
Nutrients, Vol 15, Iss 11, p 2585 (2023)
Necrotizing enterocolitis (NEC) is the leading cause of death caused by gastrointestinal disease in preterm infants. Major risk factors include prematurity, formula feeding, and gut microbial colonization. Microbes have been linked to NEC, yet there
Externí odkaz:
https://doaj.org/article/98af4acc91bb4e70b84b870ff960ad48
Autor:
Peng Wang, Peiqiang Yuan, Sen Lin, Heju Zhong, Xiaoling Zhang, Yong Zhuo, Jian Li, Lianqiang Che, Bin Feng, Yan Lin, Shengyu Xu, De Wu, Douglas G Burrin, Zhengfeng Fang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6496 (2022)
Abnormally elevated circulating bile acids (BA) during pregnancy endanger fetal survival and offspring health; however, the pathology and underlying mechanisms are poorly understood. A total of nineteen pregnant sows were randomly assigned to day 60
Externí odkaz:
https://doaj.org/article/2583ab07aee74cf780b46430f763f325
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G190-G195
Limited work has focused on fibroblast growth factor-19 (FGF19) secretion and function in the perinatal period. FGF19 is a potent growth factor that coordinates development of the brain, eye, inner ear, and skeletal system in the embryo, but after bi
Publikováno v:
Physiological Reports, Vol 8, Iss 21, Pp n/a-n/a (2020)
Abstract Background Age‐dependent changes in the intestinal gene expression of enzymes involved in the metabolism of citrulline and arginine are well characterized. Enteroids, a novel ex‐vivo model that recreates the three‐dimensional structure
Externí odkaz:
https://doaj.org/article/780a0f439b40435dbdc5af726f845d47
Autor:
Marko Rudar, Agus Suryawan, Hanh V. Nguyen, Shaji K. Chacko, Caitlin Vonderohe, Barbara Stoll, Douglas G. Burrin, Marta L. Fiorotto, Teresa A. Davis
Publikováno v:
Journal of Parenteral and Enteral Nutrition. 47:276-286
Extrauterine growth restriction is a common complication of preterm birth. Leucine (Leu) is an agonist for the mechanistic target of rapamycin (mTOR) complex 1 (mTORC1) signaling pathway that regulates translation initiation and protein synthesis in