Výsledky vyhledávání - "Douglas Florindo Pinheiro"

Akademický článek

Immune Reactions against Gene Gun Vaccines Are Differentially Modulated by Distinct Dendritic Cell Subsets in the Skin.

Autor: Corinna Stefanie Weber, Katrina Hainz, Tekalign Deressa, Helen Strandt, Douglas Florindo Pinheiro, Roberta Mittermair, Jennifer Pizarro Pesado, Josef Thalhamer, Peter Hammerl, Angelika Stoecklinger

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0128722 (2015)

The skin accommodates multiple dendritic cell (DC) subsets with remarkable functional diversity. Immune reactions are initiated and modulated by the triggering of DC by pathogen-associated or endogenous danger signals. In contrast to these processes,

Externí odkaz: https://doaj.org/article/6976cf46aef2408faffc8fee40fb2696

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The omentum harbors unique conditions in the peritoneal cavity to promote healing and regeneration for diaphragm muscle repair in mdx mice

Autor: Rafael Ferreira da Silva, Douglas Florindo Pinheiro, Thereza Quirico-Santos, Jaciara F. G. Gama, Jussara Lagrota-Candido

Publikováno v: Cell and tissue research. 382(3)

Although the primary cause of Duchenne muscular dystrophy (DMD) is a genetic mutation, the inflammatory response contributes directly to severity and exacerbation of the diaphragm muscle pathology. The omentum is a lymphoid organ with unique structur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6e3731c6c703ac4a9c8cf4ddca8a37
https://pubmed.ncbi.nlm.nih.gov/32661578

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Omentum acts as a regulatory organ controlling skeletal muscle repair of mdx mice diaphragm

Autor: Jussara Lagrota-Candido, Thiago Morais Barbosa, Douglas Florindo Pinheiro, Aline C. Gomes, Jaciara F. G. Gama, Rafael Ferreira da Silva, Thereza Quirico-Santos

Publikováno v: Cell and tissue research. 377(2)

Duchenne muscular dystrophy is a lethal X-linked muscle wasting disease due to mutations of the dystrophin gene leading to distinct susceptibility to degeneration and fibrosis among skeletal muscles. This study aims at verifying whether intense mdx d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8485427f645d431d964d7f491e8c4b61
https://pubmed.ncbi.nlm.nih.gov/30953145

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Neoantigen Expression in Steady-State Langerhans Cells Induces CTL Tolerance

Autor: Helen, Strandt, Douglas Florindo, Pinheiro, Daniel H, Kaplan, Dagmar, Wirth, Iris Karina, Gratz, Peter, Hammerl, Josef, Thalhamer, Angelika, Stoecklinger

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 199(5)

The skin hosts a variety of dendritic cells (DCs), which act as professional APC to control cutaneous immunity. Langerhans cells (LCs) are the only DC subset in the healthy epidermis. However, due to the complexity of the skin DC network, their relat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37652c542e6736ab00c9b5221095335b
https://pubmed.ncbi.nlm.nih.gov/28739880

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Nicotinic acetylcholine receptor activation reduces skeletal muscle inflammation of mdx mice

Autor: Paulo Emílio Corrêa Leite, Edna N. Yamasaki, Louise Moraes, Douglas Florindo Pinheiro, Rafael Ferreira da Silva, Jussara Lagrota-Candido, Thereza Quirico-Santos, Livia D'Elia

Publikováno v: Journal of Neuroimmunology. 227:44-51

Mdx mice develop an inflammatory myopathy characterized at different ages by myonecrosis with scattered inflammatory infiltrates followed by muscular regeneration and later persistent fibrosis. This work aimed to verify the putative anti-inflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1007452a88c87623f5b654402e35744b
https://doi.org/10.1016/j.jneuroim.2010.06.005

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Characteristic pattern of skeletal muscle remodelling in different mouse strains

Autor: Francisco J Guimarães-Joca, Luana Paula Santos-Silva, Thereza Quirico-Santos, Rafael S Ferreira, Douglas Florindo Pinheiro, Jussara Lagrota-Candido, Joseli Lannes-Vieira, Isabella Canella

Publikováno v: International Journal of Experimental Pathology. 91:522-529

Muscular injury associated with local inflammatory reaction frequently occurs in sports medicine, but the individual response and capacity of regeneration vary among subjects. Inflammatory cytokines are probably implicated in activation of repair mec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b6d4064e9673ed7cb2aafe171194eeb
https://doi.org/10.1111/j.1365-2613.2010.00737.x

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APRIL promotes breast tumor growth and metastasis and is associated with aggressive basal breast cancer

Autor: Michael Hahne, Douglas Florindo-Pinheiro, Eva González-Suárez, Araceli García-Castro, Manuela Zonca, Burgo Gutiérrez del Burgo, Aránzazu García-Grande, Alex Cordero, Carla E. Carvalho-Pinto, Santos Mañes, Lourdes Planelles

Publikováno v: Carcinogenesis
Carcinogenesis, Oxford University Press (OUP), 2015, 36 (5), pp.574--84. ⟨10.1093/carcin/bgv020⟩

APRIL (a proliferation-inducing ligand) is a cytokine of the tumor necrosis factor family associated mainly with hematologic malignancies. APRIL is also overexpressed in breast carcinoma tissue lesions, although neither its role in breast tumorigenes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f725bdca9329096ef8eda3d09965f82a
https://hal.archives-ouvertes.fr/hal-02187395

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Immune Reactions against Gene Gun Vaccines Are Differentially Modulated by Distinct Dendritic Cell Subsets in the Skin

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0128722 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f927bfc8005c8e110962317a9946c77d
https://pubmed.ncbi.nlm.nih.gov/26030383

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Persistent activation of omentum influences the pattern of muscular lesion in the mdx diaphragm

Autor: Ricardo dos Santos Pereira, Paulo Emílio Corrêa Leite, Eustáquio Luiz Paiva-Oliveira, Rafael Ferreira da Silva, Lian Pontes de Carvalho, Maria De Fatima B. Pinho, Jussara Lagrota-Candido, Thereza Quirico-Santos, Douglas Florindo Pinheiro

Publikováno v: Cell and tissue research. 350(1)

The mdx (X chromosome-linked muscular dystrophy) mouse develops a multi-staged disorder characterized by muscle degeneration and reactive fibrosis. Skeletal muscles of mdx mice are not equally susceptible to degeneration. The aim of this study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36826ded64ce963ea85e0c28069a32d3
https://pubmed.ncbi.nlm.nih.gov/22688955

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