Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Douglas F. Martin"'
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 18:1115-1121
The rat 9L brain tumor model was used to investigate the therapeutic potential of a combined modality approach using intracranial Bleomycin and radiation therapy. Bolus Bleomycin was delivered intracranially into the tumor volume via cannula guides;
Publikováno v:
Radiotherapy and Oncology. 2:57-64
Summary Paired determinations of the radiation responses of normally-aerated and artificially hypoxic rodent tumors, performed to measure the hypoxic fractions of the tumors, were obtained from our own laboratories and from the literature. The data w
Publikováno v:
European Journal of Cancer and Clinical Oncology. 19:791-797
A method has been developed for the in vitro assay of the survival of BA1112 rat sarcoma cells following treatment in vivo. The BA1112 tumor was not adapted for growth in culture and was maintained by serial transplantation in vivo. The assay used a
Autor:
James J. Fischer, Douglas F. Martin
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 10:1903-1906
The radiation response of cultured rabbit aortic endothelial cells was measured using colony formation to determine survival. The dose survival curve was qualitatively similar to those reported for other cell types. At doses of 400 rad and greater, t
Publikováno v:
Radiotherapy and Oncology. 5:311-319
Summary Acute hypoxia is often induced in rodent tumors during studies of the oxygenation or the therapeutic responses of the tumors, either by clamping the blood supply to the tumors or by asphyxiating the hosts with nitrogen. Analyses of data from
Publikováno v:
Radiology. 152:801-803
Delivery of continuous low-dose-rate radiation at a constant rate using an after-loading plastic helmet system can achieve the local cure of the BA1112 rat sarcoma. Complete dose response curves for local tumor cure have been obtained at 170 rad (1.7
Autor:
Douglas F. Martin, G.Nigel Godson
Publikováno v:
Biochemical and biophysical research communications. 65(1)
Summary When Escherichia coli is infected with X174, the host cell DNA replication ceases 10 – 12 minutes after infection. This shut-off is prevented by the addition of 30μg/ml chloramphenicol indicating a requirement for post-infection protein sy
Publikováno v:
International journal of radiation oncology, biology, physics. 13(5)
The presence of radioresistant hypoxic cells in tumors is believed to be one of the limiting factors in achieving local tumor control by radiotherapy. Treatment with hyperbaric oxygen during irradiation has been shown to improve the radiation respons
Publikováno v:
International journal of radiation oncology, biology, physics. 12(1)
It has been postulated that tumors contain hypoxic cells of decreased radiation sensitivity, which limit curability with radiation therapy. Hyperbaric oxygen has been used in an attempt to improve tumor oxygenation. The nature of the oxygen concentra
Autor:
Sara Rockwel, Carolyn G. Irvin, Douglas F. Martin, Andrew Photiou, Elizabeth Porter, Marianne Nierenburg, James J. Fische, Hiroko Yabuki
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 13:110-111