Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Douglas F. Larson"'
Autor:
Beenish Majeed, Supannikar Tawinwung, Lance S. Eberson, Timothy W. Secomb, Nicolas Larmonier, Douglas F. Larson
Publikováno v:
International Journal of Hypertension, Vol 2014 (2014)
Adaptive immune function is implicated in the pathogenesis of vascular disease. Inhibition of T-lymphocyte function has been shown to reduce hypertension, target-organ damage, and vascular stiffness. To study the role of immune inhibitory cells, CD4+
Externí odkaz:
https://doaj.org/article/ce2d6e5d6e374bdeadb9d04f8e078d32
Autor:
Beenish A. Majeed, Lance S. Eberson, Supannikar eTawinwung, Nicolas eLarmonier, Timothy W. Secomb, Douglas F Larson
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
The immune system is suggested to be essential in vascular remodeling and stiffening. To study the dependence upon lymphocytes in vascular stiffening, we compared an angiotensin II-model of vascular stiffening in normal C57BL/6J mice with lymphocyte-
Externí odkaz:
https://doaj.org/article/da4838cc89e8443aacaf329b44617732
Autor:
Lance S Eberson, Pablo A Sanchez, Beenish A Majeed, Supannikar Tawinwung, Timothy W Secomb, Douglas F Larson
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124013 (2015)
It is well accepted that angiotensin II (Ang II) induces altered vascular stiffness through responses including both structural and material remodeling. Concurrent with remodeling is the induction of the enzyme lysyl oxidase (LOX) through which ECM p
Externí odkaz:
https://doaj.org/article/79db3b76caaa42db8c87647d941c960f
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60580 (2013)
Diastolic dysfunction is the hemodynamic hallmark of hypertensive heart disease. Tau (τ) has been used to describe left ventricle relaxation. The relationship between τ and afterload has been controversial. Our goal was to demonstrate this relation
Externí odkaz:
https://doaj.org/article/ac77fabce81a4385a1b157fc44c1ecff
Autor:
Edward W. Betterton, Katrina J. DeCook, Daniel Burkhoff, Jessica R. Crosby, Zain Khalpey, Marvin J. Slepian, Richard G. Smith, Phat L. Tran, Douglas F. Larson
Publikováno v:
Artificial Organs. 41:E52-E65
With the growth and diversity of mechanical circulatory support (MCS) systems entering clinical use, a need exists for a robust mock circulation system capable of reliably emulating and reproducing physiologic as well as pathophysiologic states for u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a07d226b7483e590221c846b4e41d194
https://doi.org/10.1111/aor.12808
https://doi.org/10.1111/aor.12808
Autor:
Jane A. Leopold, Francesca Seta, Lakshmi Santhanam, Dan E. Berkowitz, John Y.-J. Shyy, David G. Harrison, Robert P. Mecham, Philip S. Tsao, Jay D. Humphrey, Jessica E. Wagenseil, Nelson Ruiz-Opazo, Douglas F. Larson, Richard A. Cohen, Zhongjie Sun, C. Alberto Figueroa, Zorina S. Galis, Young S. Oh
Publikováno v:
Circulation Research. 121:1216-1218
Large arteries (especially the aorta) lose elasticity and thicken with aging and as a consequence of other conditions, thus leading to central arterial stiffening and associated adverse effects on blood flow and pressure. Arterial stiffness can be de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586bdba2d650c04be77962d576d5d5ad
https://doi.org/10.1161/circresaha.117.311703
https://doi.org/10.1161/circresaha.117.311703
Publikováno v:
Perfusion. 31:103-110
It is clinically established that adenosine has negative chronotropic, antiarrhythmic effects and reduces arterial blood pressure. Adenosine addition to cardioplegic solutions used in cardiac operations is clinically well tolerated and has been shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8593f8211f8ee41b81644ce5af06fa14
https://doi.org/10.1177/0267659115586579
https://doi.org/10.1177/0267659115586579
Autor:
Daniel Burkhoff, Zain Khalpey, Katrina J. DeCook, Douglas F. Larson, Marvin J. Slepian, Jessica R. Crosby, Phat L. Tran, Richard G. Smith
Publikováno v:
ASAIO Journal. 61:274-281
The SynCardia total artificial heart (TAH) has emerged as an effective, life-saving bi-ventricular replacement system for a wide variety of patients with end-stage heart failure. While the clinical performance of the TAH is established, modern physio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4db944f2b5976f8f88fadae5baede7
https://doi.org/10.1097/mat.0000000000000192
https://doi.org/10.1097/mat.0000000000000192
Autor:
Jessica R, Crosby, Katrina J, DeCook, Phat L, Tran, Edward, Betterton, Richard G, Smith, Douglas F, Larson, Zain I, Khalpey, Daniel, Burkhoff, Marvin J, Slepian
Publikováno v:
Artificial organs. 41(7)
With the growth and diversity of mechanical circulatory support (MCS) systems entering clinical use, a need exists for a robust mock circulation system capable of reliably emulating and reproducing physiologic as well as pathophysiologic states for u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::651821039f36c3627776da51ad21a27e
https://pubmed.ncbi.nlm.nih.gov/27935084
https://pubmed.ncbi.nlm.nih.gov/27935084
Publikováno v:
Perfusion. 27:520-528
Intimal hyperplasia is the leading cause of long-term failure in coronary artery bypass vein grafting, coronary artery stenting, angioplasty, arteriovenous fistula for dialysis, and allograft transplantation. Intimal hyperplasia is a product of vascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565e2459b23317c7d08e18c7ac529819
https://doi.org/10.1177/0267659112452316
https://doi.org/10.1177/0267659112452316