Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Douglas F, Beach"'
Autor:
Ian W. Flinn, John G. Gribben, Ryan Jacobs, Monika Długosz-Danecka, John M. Burke, Tomasz Wróbel, Michael S. Weiss, Danielle M. Brander, Jeff P. Sharman, Peter Sportelli, Douglas F. Beach, Krzysztof Giannopoulos, Hari P. Miskin, Suman Kambhampati, Kathryn S. Kolibaba, Sebastian Grosicki, Nilanjan Ghosh, John M. Pagel, Jerome H. Goldschmidt, Tanya Siddiqi, Alexey V. Danilov, Javier Pinilla Ibarz, Jennifer L. Cultrera, Syed F. Zafar, Wojciech Jurczak, Owen A. O'Connor, Scott F. Huntington
Publikováno v:
Blood. 136:37-39
Background: Umbralisib is an oral, once-daily, novel, dual inhibitor of phosphatidylinositol-3-kinase-delta (PI3Kδ) and casein kinase-1ε (CK1ε) that exhibits improved selectivity for the delta isoform of PI3K. Ublituximab is a novel anti-CD20 mono
Autor:
Erica B. Bhavsar, Anthony R. Mato, Paul M. Barr, John M. Pagel, Ryan Jacobs, Chadi Nabhan, Jeffrey J. Pu, Joanna Rhodes, Nirav N. Shah, Clive S. Zent, Sasanka M. Handunnetti, Brian T. Hill, Alan P Skarbnik, Frederick Lansigan, Jakub Svoboda, John N. Allan, Chaitra S. Ujjani, Andre Goy, Hande H. Tuncer, Constantine S. Tam, Bruce D. Cheson, Stephen J. Schuster, Lindsey E. Roeker, Peter V. Pickens, Richard R. Furman, Danielle M. Brander, Alison R. Sehgal, Douglas F. Beach, Mazyar Shadman, Nicole Lamanna
Publikováno v:
Am J Hematol
Ibrutinib demonstrated superior response rates and survival for treatment-naïve chronic lymphocytic leukemia (CLL) patients in a pivotal study that excluded patients younger than 65 (
Autor:
Krzysztof Giannopoulos, Sebastian Grosicki, Jeff P. Sharman, Ryan Jacobs, Syed F. Zafar, Michael S. Weiss, Danielle M. Brander, Peter Sportelli, Douglas F. Beach, Scott F. Huntington, Hari P. Miskin, Owen A. O'Connor, Wojciech Jurczak, Nilanjan Ghosh, Javier Pinilla Ibarz, Ian W. Flinn, John M. Pagel, Jerome H. Goldschmidt, Monika Długosz-Danecka, Suman Kambhampati, Tanya Siddiqi, John M. Burke, Tomasz Wróbel, John G. Gribben, Mazyar Shadman, Kathryn S. Kolibaba, Alexey V. Danilov, Jennifer L. Cultrera
Publikováno v:
Blood. 138:3726-3726
Background: Umbralisib, a selective PI3Kδ and casein kinase-1epsilon (CK1ε) inhibitor, is pharmacologically distinct from other PI3K inhibitors and is administered orally once daily. Ublituximab is a novel anti-CD20 monoclonal antibody glycoenginee
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 27(12)
Autor:
Hana Aviv, Vimal Patel, Roland Schwarting, Neil A. Lachant, Douglas F. Beach, Barry L. Barnoski, Roger Strair
Publikováno v:
Cancer Genetics. 205:665-668
A nonrandom structural gain of 1q may be seen in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), and often it is due to an unbalanced translocation. Dup(1)(q21q32) as the sole abnormality has only rarely been reported. Reports have s
Autor:
Douglas F, Beach, Robert A, Somer, Jean, Hoffman-Censits, Jianqing, Lin, Yu-Ning, Wong, Elizabeth, Plimack, Elizabeth, Plimeck, Gary, Hudes, David, Vaughn, Guy T, Bernstein, Gloria J, Morris
Publikováno v:
Seminars in Oncology. 39:1-8
a t f t p p t At times we encounter clinical problems for which there are no directly applicable evidence-based solutions, but we are compelled by circumstances to act. When doing so we rely on related evidence, general principles of best medical pra
Autor:
Roland Schwarting, Douglas F. Beach, Lisa M. Reid, Alexandre Hageboutros, Ghada Haddad, William Klump
Publikováno v:
Medical Oncology. 29:1405-1408
Neuroendocrine tumors comprise a large group of malignancies which share unique morphological features and are characterized by the presence of neuroendocrine markers such as synaptophysin, chromogranin-A, and CD56 (N-CAM), ranging from indolent tumo
Autor:
Robert A. Somer, Douglas F. Beach
Publikováno v:
Journal of Clinical Oncology. 29:e397-e401
Autor:
Ohad Oren, Douglas F. Beach
Publikováno v:
Blood. 128:3593-3593
Background Non-cancerous medical conditions have a profound impact on the health of patients with malignancies. In individuals with lung cancer, the likelihood of death due to other causes is higher than that of the general population. It is therefor
Autor:
Douglas F. Beach, Ohad Oren
Publikováno v:
Journal of Clinical Oncology. 34:e18057-e18057
e18057Background: African-American (AA) men represent a unique subset of patients in prostate cancer. First, they are disproportionately affected by this cancer, with prevalence rates of 214.5 (per...