Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Douglas E. Kiehl"'
Autor:
Ian D. Henry, Kady Krivos, Christopher J. Pulliam, Vincent P. Sica, Douglas E. Kiehl, Timothy R. Baker
Publikováno v:
Mass Spectrometry Reviews. 39:212-226
In addition to degradation products, impurities, and exogenous contaminants, industries such as pharmaceutical, food, and others must concern themselves with leachables. These chemicals can derive from containers and closures or migrate from labels o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0acbe3e0da23108e335dca695ab81d67
https://doi.org/10.1002/mas.21591
https://doi.org/10.1002/mas.21591
Publikováno v:
Rapid Communications in Mass Spectrometry. 12:903-910
Monensins are a series of polyether ionophore antibiotic factors produced by Streptomyces cinnamonensis. Three monensin factors and four metabolites of monensin A isolated from cattle feces were investigated by electrospray ionization mass spectromet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::405e900d4659f9ee29991276f2ca2dc2
https://doi.org/10.1002/(sici)1097-0231(19980731)12:14<903::aid-rcm253>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19980731)12:14<903::aid-rcm253>3.0.co
Autor:
Robin S. Readnour, James Patrick Leeds, K. E. Willard, Douglas E. Kiehl, Christine M. Cleveland, Herbert A. Kirst, Paul R. Klink
Publikováno v:
Journal of Agricultural and Food Chemistry. 46:3265-3271
During formulation development of the veterinary macrolide antibiotic tilmicosin, an oxidation product of the parent molecule was identified. Use of liquid chromatography/mass spectrometry and nuclear magnetic resonance spectroscopy characterized the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73b420be13a026ca2f389aa29b6a1407
https://doi.org/10.1021/jf9710746
https://doi.org/10.1021/jf9710746
Publikováno v:
Rapid Communications in Mass Spectrometry. 11:1266-1270
Reversed phase high-performance liquid chromatography (RPHPLC) coupled with electrospray ionization mass spectrometry (ESI-MS) was used to separate and characterize the peptides resulting from the tryptic cleavage of somidobove, a recombinant bovine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3925b3e791637caeec016bbd018584ac
https://doi.org/10.1002/(sici)1097-0231(199708)11:12<1266::aid-rcm977>3.0.co
https://doi.org/10.1002/(sici)1097-0231(199708)11:12<1266::aid-rcm977>3.0.co
Autor:
Paul A. Record, David A. Dickson, Thomas Harry Ferguson, Douglas E. Kiehl, Allison S. Kennington, Jen P. Chang
Publikováno v:
Journal of Chromatography A. 736:97-104
A high-performance size-exclusion chromatographic method was developed for the determination of potency of recombinant bovine somatotropin (rbST) monomer and the estimation of dimer and soluble aggregates in bulk drug substances. These proteins can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931841b6f0ae7747faf8c84223663ed3
https://doi.org/10.1016/0021-9673(95)01284-2
https://doi.org/10.1016/0021-9673(95)01284-2
Publikováno v:
Rapid Communications in Mass Spectrometry. 9:1297-1301
Tilmicosin is a semisynthetic macrolide antibiotic used in the treatment of respiratory disease in cattle and swine. The technique of liquid chromatography/atmospheric pressure chemical ionization mass spectrometry (LC/APCI-MS) was employed in an on-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455bbaa5075b624a3baca13feacce8e5
https://doi.org/10.1002/rcm.1290091315
https://doi.org/10.1002/rcm.1290091315
Publikováno v:
The Journal of antibiotics. 56(5)
Synthesis is described for the haptens 23-demycinosyl-23-deoxy-23-(3-aminoprop-1-yl)-aminotilmicosin (6) from 5-O-mycaminosyltylonolide (OMT) and for 23-demycinosyl-23-deoxy-23-(3-aminoprop-1-yl)-amino-20-dihydrotylosin (10) from demycinosyltylosin (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfc0ba124b1b7259d0b77bd879cae51
https://pubmed.ncbi.nlm.nih.gov/12870814
https://pubmed.ncbi.nlm.nih.gov/12870814
Publikováno v:
Nature biotechnology. 20(7)
The antibacterial properties of macrolide antibiotics (such as erythromycin, tylosin, and narbomycin) depend ultimately on the glycosylation of otherwise inactive polyketide lactones. Among the sugars commonly found in such macrolides are various 6-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c251f79db8cd14bec7917e298d7daef
https://pubmed.ncbi.nlm.nih.gov/12089557
https://pubmed.ncbi.nlm.nih.gov/12089557