Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Douglas E. Horsman"'
Autor:
Jesse Shustik, Guangming Han, Pedro Farinha, Nathalie A. Johnson, Susana Ben Neriah, Joseph M. Connors, Laurie H. Sehn, Douglas E. Horsman, Randy D. Gascoyne, Christian Steidl
Publikováno v:
Haematologica, Vol 95, Iss 1 (2010)
Background BCL6 gene rearrangement is the most frequent chromosomal abnormality in diffuse large B-cell lymphoma, a malignancy characterized by genetic heterogeneity and wide variability in clinical outcome. The prognostic significance of BCL6 rearra
Externí odkaz:
https://doaj.org/article/f6b94afa20144373b3344e7a512663c6
Autor:
Douglas E. Horsman, Randy D. Gascoyne, Marco A. Marra, Carolyn Brown, Joseph M. Connors, Kerry Savage, Wan Lam, Thomas Relander, Adele Telenius, Jessica E. Paul, Hong Qian, Sohrab P. Shah, Richard Moore, Ryan D. Morin, Jacqueline Schein, Susana Ben-Neriah, Christian Steidl, Tesa Severson, Joslynn G. Affleck, Nathalie A. Johnson, K-John J. Cheung
Supplementary Table 1 from Acquired TNFRSF14 Mutations in Follicular Lymphoma Are Associated with Worse Prognosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb554a3c2f0320a1f1dacf7fd8b71cab
https://doi.org/10.1158/0008-5472.22388790.v1
https://doi.org/10.1158/0008-5472.22388790.v1
Autor:
Michelle Moksa, Angela Tam, Readman Chiu, Kane Tse, Malachi Griffith, Sa Li, Karen Mungall, Eric Y. Zhao, Barbara Meissner, Shaun D. Jackman, Bruce Woolcock, Matthew A. Field, Susanna Chan, Merrill Boyle, Martin Hirst, David W. Scott, Susana Ben-Neriah, John J. Spinelli, Yaron S.N. Butterfield, Duane E. Smailus, Allen Delaney, Marco A. Marra, Yongjun Zhao, Oleksandr Yakovenko, Sanja Rogic, Angela Brooks-Wilson, Jessica Tamura-Wells, Nathalie A. Johnson, Diane L. Trinh, Randy D. Gascoyne, Irmtraud M. Meyer, Jacqueline E. Schein, Rodrigo Goya, Suganthi Chittaranjan, Robert A. Holt, Joseph M. Connors, Andrew J. Mungall, Ryan D. Morin, Steven J.M. Jones, Maria Mendez-Lago, Marlo Firme, Tesa M. Severson, Lisa M. Rimsza, Richard A. Moore, Helen McDonald, Martin Krzywinski, Douglas E. Horsman, Thomas Zeng, Inanc Birol, Richard Corbett
Publikováno v:
Nature
Follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) are the two most common non-Hodgkin lymphomas (NHLs). Here we sequenced tumour and matched normal DNA from 13 DLBCL cases and one FL case to identify genes with mutations in B-cell NH
Autor:
Lorena Barclay, Adele Telenius, Merrill Boyle, Christian Steidl, Randy D. Gascoyne, Pedro Farinha, Douglas E. Horsman, Sohrab P. Shah, Joseph M. Connors
Publikováno v:
Blood. 116:418-427
In classical Hodgkin lymphoma (cHL) the mechanisms underlying primary refractory disease and relapse remain unknown. To gain further insight into cHL pathogenesis and genomic changes linked to treatment response, we studied 53 cHL patients by array c
Autor:
Nathalie A. Johnson, Susana Ben-Neriah, Sohrab P. Shah, Jacquie Schein, Douglas E. Horsman, Adele Telenius, Andrew J. Mungall, Merrill Boyle, Tang Lee, Betty Lai, Randy D. Gascoyne, Joseph M. Connors, Marco A. Marra, Allen Delaney, K-John Cheung, Dorothy Cheung
Publikováno v:
Genes, Chromosomes and Cancer. 49:669-681
A multiplatform approach, including conventional cytogenetic techniques, BAC array comparative genomic hybridization, and Affymetrix 500K SNP arrays, was applied to the study of the tumor genomes of 25 follicular lymphoma biopsy samples with paired n
Autor:
Hong Qian, Ryan D. Morin, Inanc Birol, Tesa M. Severson, Richard Varhol, Bruce Woolcock, Yongjun Zhao, Richard Corbett, Florian Kuchenbauer, Charlot Jf, Rodrigo Goya, Tcherpakov M, Joseph M. Connors, Marco A. Marra, Douglas E. Horsman, Randy D. Gascoyne, Nathalie A. Johnson, Robert A. Holt, Richard A. Moore, Andrew J. Mungall, Allen Delaney, Samuel Aparicio, Angela K Y Tam, Hao Zhu, Michelle Moksa, Jacquie Schein, Shashkin P, Martin Hirst, Damian Yap, Jianghong An, Steven J.M. Jones, Kimbara M, Humphries Rk, Paul Je, Merrill Boyle, Obi L. Griffith, Sohrab P. Shah, Duane E Smailus
Publikováno v:
Nature genetics
Follicular lymphoma (FL) and the GCB subtype of diffuse large B-cell lymphoma (DLBCL) derive from germinal center B cells. Targeted resequencing studies have revealed mutations in various genes encoding proteins in the NF-kappaB pathway that contribu
Autor:
Pedro Farinha, Randy D. Gascoyne, Kerry J. Savage, Nathalie A. Johnson, Susana Ben-Neriah, Joseph M. Connors, Laurie H. Sehn, Douglas E. Horsman
Publikováno v:
Blood. 114:3533-3537
Approximately 5% to 10% of diffuse large B-cell lymphomas (DLBCLs) harbor an MYC oncogene rearrangement (MYC+). The prognostic significance of MYC+ DLBCL was determined in an unselected population of patients with newly diagnosed DLBCL treated with r
Autor:
Guangming Han, Pedro Farinha, Joseph M. Connors, Nathalie A. Johnson, Christian Steidl, Jesse Shustik, Susana Ben Neriah, Randy D. Gascoyne, Laurie H. Sehn, Douglas E. Horsman
Publikováno v:
PubMed Central
Background BCL6 gene rearrangement is the most frequent chromosomal abnormality in diffuse large B-cell lymphoma, a malignancy characterized by genetic heterogeneity and wide variability in clinical outcome. The prognostic significance of BCL6 rearra
Autor:
Tommy Fu, Esther Masih-Khan, Helene Bruyere, Young Trieu, Douglas E. Horsman, Donna E. Reece, Nizar J. Bahlis, Kevin W. Song, Adnan Mansoor, Christine Chen, Birgitte Roland, Douglas A. Stewart, Hong Chang
Publikováno v:
Blood. 114:522-525
Although the combination of lenalidomide and dexamethasone is effective therapy for patients with relapsed/refractory multiple myeloma, the influence of high-risk cytogenetic abnormalities on outcomes is unknown. This subanalysis of a large, open-lab
Autor:
Raymond T. Ng, Sohrab P. Shah, Kevin Murphy, K-John Cheung, Randy D. Gascoyne, Douglas E. Horsman, Guillaume Alain, Nathalie A. Johnson
Publikováno v:
Bioinformatics
Motivation: Analysis of array comparative genomic hybridization (aCGH) data for recurrent DNA copy number alterations from a cohort of patients can yield distinct sets of molecular signatures or profiles. This can be due to the presence of heterogene