Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Douglas E Brown"'
Publikováno v:
Critical Care Explorations, Vol 4, Iss 7, p e0706 (2022)
OBJECTIVES:. Limiting or withdrawing nonbeneficial medical care is considered ethically responsible throughout most of critical care and medical ethics literature. Practically, however, setting limits to treatment is often challenging. We review the
Externí odkaz:
https://doaj.org/article/19af23837aa1411f9ec4af618c75ddcb
Autor:
Piroska K. Kopar, MD, Jessica B. Kramer, MD, Douglas E. Brown, PhD, Grant V. Bochicchio, MD, MPH
Publikováno v:
Critical Care Explorations, Vol 3, Iss 1, p e0326 (2021)
Objectives:. A cornerstone of our healthcare system’s response to the coronavirus disease 2019 pandemic is widespread testing to facilitate both isolation and early treatment. When patients refuse to undergo coronavirus disease testing, they compro
Externí odkaz:
https://doaj.org/article/eea14f9aea2a4ee3b79a3cbd570cb141
Publikováno v:
MedChemComm. 4:269-277
Two-component signal transduction systems (TCSs) are commonly used by bacteria to couple environmental stimuli to adaptive responses. Targeting the highly conserved kinase domain in these systems represents a promising strategy for the design of a br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c36c3b08d19f1a85ff4c563c74a8c3
https://doi.org/10.1039/c2md20308a
https://doi.org/10.1039/c2md20308a
Autor:
Abigail A. Lamikanra, Alexandre J. Potocnik, Douglas E. Brown, Climent Casals-Pascual, David J. Roberts, Jean Langhorne
Severe malaria is manifest by a variety of clinical syndromes dependent on properties of both the host and the parasite. In young infants, severe malarial anemia (SMA) is the most common syndrome of severe disease and contributes substantially to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c519ed27e7e3c10794b66d4ea268ec42
https://doi.org/10.1182/blood-2006-09-018069
https://doi.org/10.1182/blood-2006-09-018069
Autor:
Shaowu Meng, Cassie A. Nelson, Yeonyee Oh, Ralph A. Dean, Minfeng Xue, Douglas E Brown, Thomas Creighton Mitchell, Cristiano C. Nunes, Joshua K. Sailsbery, Feng Chen, Curt H. Hagedorn, Malali Gowda
Publikováno v:
Nucleic Acids Research
Small RNAs are well described in higher eukaryotes such as mammals and plants; however, knowledge in simple eukaryotes such as filamentous fungi is limited. In this study, we discovered and characterized methylguanosine-capped and polyadenylated smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5652d0d177efc7ef743429cc4eaaa69
https://doi.org/10.1093/nar/gkq583
https://doi.org/10.1093/nar/gkq583
Publikováno v:
Expert Reviews in Molecular Medicine. 8:1-22
Malaria kills approximately 1–2 million people every year, mostly in sub-Saharan Africa and in Asia. These deaths are at the most severe end of a scale of pathologies affecting approximately 500 million people per year. Much of the pathogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff9dec33497f8ed01948f74f8b9a49c
https://doi.org/10.1017/s1462399406010581
https://doi.org/10.1017/s1462399406010581
Autor:
Michael Heuer, Steven B. Cannon, Ethalinda K. S. Cannon, Dong-Jin Kim, Andrew Cook, Anne Francoise Lamblin, Jayprakash Vasdewani, Christopher D. Town, Ernest F. Retzel, Christopher Dwan, Bruce A. Roe, Douglas R. Cook, Joann Mudge, Steve Kenton, Foo Cheung, Timothy M. Kunau, John A. Crow, John Gish, Xiaohong Wang, Gregory D. May, Nevin D. Young, Douglas E Brown
Publikováno v:
Plant Physiology. 138:38-46
An international consortium is sequencing the euchromatic genespace of Medicago truncatula. Extensive bioinformatic and database resources support the marker-anchored bacterial artificial chromosome (BAC) sequencing strategy. Existing physical and ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::534640b71eceb5257ecd2dca0b211aa2
https://doi.org/10.1104/pp.104.059204
https://doi.org/10.1104/pp.104.059204
Autor:
Ralph A. Dean, Thomas K. Mitchell, Ravi Rajagopalan, Stanton L. Martin, Rod A. Wing, Douglas E Brown, Robert G. Sceeles, Sheila O. Denn, Barbara P. Blackmon, Thomas D. Houfek
Publikováno v:
Nucleic Acids Research. 30:121-124
We have created a federated database for genome studies of Magnaporthe grisea, the causal agent of rice blast disease, by integrating end sequence data from BAC clones, genetic marker data and BAC contig assembly data. A library of 9216 BAC clones pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a107786ecb753c596501f5a12430b2
https://doi.org/10.1093/nar/30.1.121
https://doi.org/10.1093/nar/30.1.121
Publikováno v:
Macromolecules. 34:2870-2875
The vinyloxycyclophosphazene derivatives, N3P3Cl5OCHCH2 (1) and N4P4Cl7OCHCH2 (6), undergo radical polymerization to produce the highly functionalized homopolymers [CH(ON3P3Cl5)CH2]n (7) and [CH(ON4P4Cl7)CH2]n (8). These materials undergo a remarkabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::175ad8c069f43acdab666f6478739c06
https://doi.org/10.1021/ma001911w
https://doi.org/10.1021/ma001911w
Publikováno v:
Inorganic Chemistry. 39:810-814
The syntheses of the vinyloxycyclotriphosphazene derivatives N3P3X5OCHCH2 (X = OMe, OCH2CF3) and the N3P3(NMe2)4(OCHCH2)2 isomeric mixture along with improved preparations of N3P3X5OCHCH2 (X = F, NMe2) are reported. The interactions between the vinyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::512c112a93fea001c666f42171dd9738
https://doi.org/10.1021/ic990406g
https://doi.org/10.1021/ic990406g