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pro vyhledávání: '"Douglas Den Otter"'
Autor:
Mallika Singh, Klaus P. Hoeflich, Mark Merchant, Richard Carano, Dorothy French, Michelle A. Nannini, William Forrest, Tim Cao, Hani Bou-Reslan, Emily Chan, Douglas Den Otter, Anne C. Clermont, Ciara Metcalfe, Joseph Castillo, Jason H. Cheng, Vidusha Devasthali, Melissa R. Junttila
Supplemental Fig 1,2,3. Tumor growth rates, overall survival and single agent GDC-0973 in vitro response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71abcd86d84e987877a60f47e42d7d98
https://doi.org/10.1158/1535-7163.22501464
https://doi.org/10.1158/1535-7163.22501464
Autor:
Mallika Singh, Klaus P. Hoeflich, Mark Merchant, Richard Carano, Dorothy French, Michelle A. Nannini, William Forrest, Tim Cao, Hani Bou-Reslan, Emily Chan, Douglas Den Otter, Anne C. Clermont, Ciara Metcalfe, Joseph Castillo, Jason H. Cheng, Vidusha Devasthali, Melissa R. Junttila
Activating mutations in the KRAS oncogene occur in approximately 90% of pancreatic cancers, resulting in aberrant activation of the MAPK and the PI3K pathways, driving malignant progression. Significant efforts to develop targeted inhibitors of nodes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec601dfc57c36d50faff96ead5e30713
https://doi.org/10.1158/1535-7163.c.6536796.v1
https://doi.org/10.1158/1535-7163.c.6536796.v1
Autor:
Jason H. Cheng, Douglas Den Otter, Hani Bou-Reslan, Vidusha Devasthali, Richard A.D. Carano, Emily Chan, Klaus P. Hoeflich, Anne C Clermont, Michelle Nannini, Mallika Singh, Ciara Metcalfe, Mark Merchant, Dorothy French, Joseph Castillo, Melissa R. Junttila, Tim C. Cao, William F. Forrest
Publikováno v:
Molecular Cancer Therapeutics. 14:40-47
Activating mutations in the KRAS oncogene occur in approximately 90% of pancreatic cancers, resulting in aberrant activation of the MAPK and the PI3K pathways, driving malignant progression. Significant efforts to develop targeted inhibitors of nodes