Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Douglas D, Thomas"'
Autor:
Hannah Petraitis Kuschman, Marianne B. Palczewski, Brian Hoffman, Mary Menhart, Xiaowei Wang, Sharon Glynn, Abul B.M.M.K. Islam, Elizaveta V. Benevolenskaya, Douglas D. Thomas
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102928- (2023)
N6-methyladenosine (m6A) is the most abundant internal modification on eukaryotic mRNAs. Demethylation of m6A on mRNA is catalyzed by the enzyme fat mass and obesity-associated protein (FTO), a member of the nonheme Fe(II) and 2-oxoglutarate (2-OG)-d
Externí odkaz:
https://doaj.org/article/caa9b3a2fe4d401185bf68d9d22e568f
Publikováno v:
Redox Biology, Vol 15, Iss C, Pp 277-283 (2018)
Nitrite represents an endocrine reserve of bioavailable nitric oxide (NO) that mediates a number of physiological responses including conferral of cytoprotection after ischemia/reperfusion (I/R). It has long been known that nitrite can react with non
Externí odkaz:
https://doaj.org/article/ba520420fda74aef82957c914e8c8904
Autor:
Douglas D. Thomas, Benjamin A. Garcia, Mark Maienschein-Cline, Xing-Jun Cao, Pinal Kanabar, Neil Bahroos, Lin L. Mantell, Vy Pham, Rhea C. Bovee, Jason R. Hickok, Divya Vasudevan
GO terms associated with upregulated genes bearing new ∙NO-induced H3K9ac peaks around promoter regions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ac0dc2cf6f8fa544f58e5a6a6e9aa2
https://doi.org/10.1158/0008-5472.22407872
https://doi.org/10.1158/0008-5472.22407872
Autor:
Douglas D. Thomas, Benjamin A. Garcia, Mark Maienschein-Cline, Xing-Jun Cao, Pinal Kanabar, Neil Bahroos, Lin L. Mantell, Vy Pham, Rhea C. Bovee, Jason R. Hickok, Divya Vasudevan
Supplementary Materials and Methods. Figure S1. Nitric oxide induces significant changes in histone posttranslational modifications. Figure S2. NO-mediated gene expression changes are consistent with the induction of an oncogenic phenotype. Figure S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98812b65f6f9f58db34898fe47c8ab3f
https://doi.org/10.1158/0008-5472.22407869.v1
https://doi.org/10.1158/0008-5472.22407869.v1
Autor:
Douglas D. Thomas
Publikováno v:
Redox Biology, Vol 5, Iss , Pp 225-233 (2015)
Nitric oxide (•NO, nitrogen monoxide) is one of the most unique biological signaling molecules associated with a multitude of physiologic and pathological conditions. In order to fully appreciate its numerous roles, it is essential to understand it
Externí odkaz:
https://doaj.org/article/ec4ec8ae2c7b4a96bfc84662b993c2e6
Publikováno v:
Free Radical Biology and Medicine. 170:34-43
Nitric oxide (NO) and hydrogen sulfide (H2S) were previously only known for their toxic properties. Now they are regarded as potent gaseous messenger molecules (gasotransmitters) that rapidly transverse cell membranes and transduce cellular signals t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bd97611647466d56d07eeac4c10c79
https://doi.org/10.1016/j.freeradbiomed.2021.01.010
https://doi.org/10.1016/j.freeradbiomed.2021.01.010
Publikováno v:
Redox Biology, Vol 1, Iss 1, Pp 203-209 (2013)
Nitric oxide (·NO) is a biologically important short-lived free radical signaling molecule. Both the enzymatic synthesis and the predominant forms of cellular metabolism of ·NO are oxygen-dependent. For these reasons, changes in local oxygen concen
Externí odkaz:
https://doaj.org/article/8d6f199c467e4f32965fe774e101cada
Autor:
Douglas D. Thomas, Sruti Shiva
Publikováno v:
Nitric oxide : biology and chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732aefb0c88d0dc25ff369610d8bbe17
https://pubmed.ncbi.nlm.nih.gov/35276325
https://pubmed.ncbi.nlm.nih.gov/35276325
Publikováno v:
Current Opinion in Physiology. 9:94-99
Nitric oxide (nitrogen monoxide, NO) is an endogenously produced signaling molecule in cancer that regulates gene expression and cell phenotype. In recent years, new evidence has emerged regarding the roles of NO in epigenetic regulation and specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8abc73e0bfdf59c82b8e9b45cd2a74c
https://doi.org/10.1016/j.cophys.2019.05.006
https://doi.org/10.1016/j.cophys.2019.05.006
Autor:
Mayumi Fujita, Debashree Basudhar, Lisa A. Ridnour, Stephen K. Anderson, Jae Hong No, Veena Somasundaram, Gaurav Bharadwaj, Douglas D. Thomas, Robert Y.S. Cheng, David A. Wink, Daniel W. McVicar
Publikováno v:
Antioxidants & Redox Signaling. 30:1124-1143
Significance: Cancer is a complex disease, which not only involves the tumor but its microenvironment comprising different immune cells as well. Nitric oxide (NO) plays specific roles within tumor cells and the microenvironment and determines the rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62adc86cc6ba2dcc2a618d1ba5a1a6b8
https://doi.org/10.1089/ars.2018.7527
https://doi.org/10.1089/ars.2018.7527