Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Douglas C Weiser"'
Autor:
Vaishali Jayashankar, Michael J Nguyen, Brandon W Carr, Dale C Zheng, Joseph B Rosales, Joshua B Rosales, Douglas C Weiser
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75766 (2013)
BackgroundThe myosin phosphatase is a highly conserved regulator of actomyosin contractility. Zebrafish has emerged as an ideal model system to study the in vivo role of myosin phosphatase in controlling cell contractility, cell movement and epitheli
Externí odkaz:
https://doaj.org/article/923b3f0e633242148174a41e1dd00759
Autor:
Kelsey A, Oonk, Lauren B, Bienvenu, Paxton S, Sickler, Christine, Martin, Emily, Nickoloff-Bybel, Albert Matthew, Volk, Douglas C, Weiser, Susan, Walsh
Publikováno v:
microPublication Biology
Inside a cell, mitochondria are organelles that exhibit dynamic locomotion and spatial rearrangement (Cai and Sheng 2009; Sheng 2017). This movement is necessary for a cell to maintain basic metabolic functions, and disruption of this motility often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2508537d30309334ceb80a044244566b
http://europepmc.org/articles/PMC7704262
http://europepmc.org/articles/PMC7704262
Autor:
Irene Lang, Alisa Arata, Guneet Virk, Jason Young, Dale C. Zheng, Douglas C. Weiser, Michael J. Nguyen, Michelle Fong, Susan Walsh, Katia S. Chadaideh, Rojin Amiri
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 5709, p 5709 (2020)
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5709, p 5709 (2020)
Volume 21
Issue 16
The Cpi-17 (ppp1r14) gene family is an evolutionarily conserved, vertebrate specific group of protein phosphatase 1 (PP1) inhibitors. When phosphorylated, Cpi-17 is a potent inhibitor of myosin phosphatase (MP), a holoenzyme complex of the regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39fb040de1742888ba8ebb8177ed56ce
http://europepmc.org/articles/PMC7460850
http://europepmc.org/articles/PMC7460850
Publikováno v:
Gene. 675:15-26
Myosin phosphatase is an evolutionarily conserved regulator of actomyosin contractility, comprised of a regulatory subunit (Mypt1), and a catalytic subunit (PP1). Zebrafish has become an ideal model organism for the study of the genetic and cell phys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698089d690803b8ecbab526d585df0c0
https://doi.org/10.1016/j.gene.2018.06.092
https://doi.org/10.1016/j.gene.2018.06.092
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10712 (2010)
Septins are involved in a number of cellular processes including cytokinesis and organization of the cytoskeleton. Alterations in human septin-9 (SEPT9) levels have been linked to multiple cancers, whereas mutations in SEPT9 cause the episodic neurop
Externí odkaz:
https://doaj.org/article/0b2f9deeaea54d0889e795907070fd7f
Publikováno v:
Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology. 191
Mitochondria exhibit dynamic locomotion and spatial rearrangement. This movement is necessary for a cell to maintain basic metabolic functions, and disruption of motility often results in cell death. Miro is a mitochondrial outer membrane Rho GTPase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a89b2170565eed2cc0ceb70cad6ef79
https://pubmed.ncbi.nlm.nih.gov/26482085
https://pubmed.ncbi.nlm.nih.gov/26482085
Publikováno v:
Journal of Biological Chemistry. 279:48904-48914
Inhibitor-1 (I-1) is a selective inhibitor of protein phosphatase-1 (PP1) and regulates several PP1-dependent signaling pathways, including cardiac contractility and regulation of learning and memory. The human I-1 gene has been spliced to generate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::063d0474627be4d5b4b6cf6d7ae0a45d
https://doi.org/10.1074/jbc.m404416200
https://doi.org/10.1074/jbc.m404416200
Autor:
Sally Kornbluth, Douglas C. Weiser, Seth S. Margolis, Minoru Yoshida, Susan Walsh, Shirish Shenolikar
Publikováno v:
The EMBO Journal. 22:5734-5745
It has been known for over a decade that inhibition of protein phosphatase 1 (PP1) activity prevents entry into M phase, but the relevant substrate has not been identified. We report here that PP1 is required for dephosphorylation of the Cdc2-directe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330a3ffd8ed225afa5b7c0c13ed3c811
https://doi.org/10.1093/emboj/cdg545
https://doi.org/10.1093/emboj/cdg545
Publikováno v:
International Journal of Molecular Sciences
Volume 15
Issue 7
Pages 11597-11613
International Journal of Molecular Sciences, Vol 15, Iss 7, Pp 11597-11613 (2014)
Volume 15
Issue 7
Pages 11597-11613
International Journal of Molecular Sciences, Vol 15, Iss 7, Pp 11597-11613 (2014)
Zipper-interacting protein kinase (ZIPK) is a conserved vertebrate-specific regulator of actomyosin contractility in smooth muscle and non-muscle cells. Murine ZIPK has undergone an unusual divergence in sequence and regulation compared to other ZIPK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc68339918aa026ac470e87d706383b
https://pubmed.ncbi.nlm.nih.gov/24983477
https://pubmed.ncbi.nlm.nih.gov/24983477
Autor:
Joshua B. Rosales, Brandon W. Carr, Michael J. Nguyen, Douglas C. Weiser, Joseph B. Rosales, Vaishali Jayashankar, Dale C. Zheng
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e75766 (2013)
PLoS ONE, Vol 8, Iss 9, p e75766 (2013)
BackgroundThe myosin phosphatase is a highly conserved regulator of actomyosin contractility. Zebrafish has emerged as an ideal model system to study the in vivo role of myosin phosphatase in controlling cell contractility, cell movement and epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebf5643ffa786b5ac8af73d08d8db20
https://pubmed.ncbi.nlm.nih.gov/24040418
https://pubmed.ncbi.nlm.nih.gov/24040418